flurbiprofen has been researched along with Glioblastoma in 3 studies
Flurbiprofen: An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
flurbiprofen : A monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "R-Flurbiprofen is a nonsteroidal antienflammatory drug and has potential anticancer activity." | 5.56 | Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration. ( Caban-Toktas, S; Capan, Y; Dalkara, T; Esendagli, G; Karlı Oguz, K; Khan, M; Lule, S; Mut, M; Sahin, A; Soylemezoglu, F; Vural, I, 2020) |
| " Flurbiprofen, indomethacin and other NSAIDs stimulated 15-PGDH activity in colon cancer HT29 cells as well as in lung cancer A549 cells and glioblastoma T98G cells." | 4.87 | Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). ( Chi, X; Tai, HH; Tong, M, 2011) |
| " In an attempt to find an effective treatment, we examined the efficacy of the non-steroidal anti-inflammatory drug, flurbiprofen, to suppress the growth of tumor cell lines derived from medulloblastoma and glioblastoma multiforme." | 3.71 | Inhibition of human brain tumor cell growth by the anti-inflammatory drug, flurbiprofen. ( Khalili, K; King, JG, 2001) |
| "R-Flurbiprofen is a nonsteroidal antienflammatory drug and has potential anticancer activity." | 1.56 | Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration. ( Caban-Toktas, S; Capan, Y; Dalkara, T; Esendagli, G; Karlı Oguz, K; Khan, M; Lule, S; Mut, M; Sahin, A; Soylemezoglu, F; Vural, I, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Caban-Toktas, S | 1 |
| Sahin, A | 1 |
| Lule, S | 1 |
| Esendagli, G | 1 |
| Vural, I | 1 |
| Karlı Oguz, K | 1 |
| Soylemezoglu, F | 1 |
| Mut, M | 1 |
| Dalkara, T | 1 |
| Khan, M | 1 |
| Capan, Y | 1 |
| Tai, HH | 1 |
| Chi, X | 1 |
| Tong, M | 1 |
| King, JG | 1 |
| Khalili, K | 1 |
1 review available for flurbiprofen and Glioblastoma
| Article | Year |
|---|---|
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, | 2011 |
2 other studies available for flurbiprofen and Glioblastoma
| Article | Year |
|---|---|
Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Cell Surv | 2020 |
Inhibition of human brain tumor cell growth by the anti-inflammatory drug, flurbiprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Neoplasms; Cell Cycle; Cell Division; Cyclin B; Cyclo | 2001 |