bumetanide has been researched along with Glioblastoma in 3 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, temozolomide (TMZ) triggered loss of K(+)(i) and Cl(-)(i) and AVD in primary glioblastoma multiforme (GBM) cancer cells (GC) and GC cancer stem cells (GSC)." | 7.78 | Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells. ( Algharabil, J; Begum, G; Clark, PA; Kahle, KT; Kintner, DB; Kuo, JS; Lin, SH; Sun, D; Wang, Q; Yang, SS, 2012) |
| " In the present study, temozolomide (TMZ) triggered loss of K(+)(i) and Cl(-)(i) and AVD in primary glioblastoma multiforme (GBM) cancer cells (GC) and GC cancer stem cells (GSC)." | 3.78 | Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells. ( Algharabil, J; Begum, G; Clark, PA; Kahle, KT; Kintner, DB; Kuo, JS; Lin, SH; Sun, D; Wang, Q; Yang, SS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Habela, CW | 1 |
| Ernest, NJ | 2 |
| Swindall, AF | 1 |
| Sontheimer, H | 2 |
| Algharabil, J | 1 |
| Kintner, DB | 1 |
| Wang, Q | 1 |
| Begum, G | 1 |
| Clark, PA | 1 |
| Yang, SS | 1 |
| Lin, SH | 1 |
| Kahle, KT | 1 |
| Kuo, JS | 1 |
| Sun, D | 1 |
3 other studies available for bumetanide and Glioblastoma
| Article | Year |
|---|---|
Chloride accumulation drives volume dynamics underlying cell proliferation and migration.
Topics: Acetates; Analysis of Variance; Bumetanide; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cel | 2009 |
Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells.
Topics: Apoptosis; Bumetanide; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Proliferation; Cell Size; Chlori | 2012 |
Extracellular glutamine is a critical modulator for regulatory volume increase in human glioma cells.
Topics: Blotting, Western; Bumetanide; Cell Line, Tumor; Cell Size; Extracellular Space; Gene Expression; Gl | 2007 |