Page last updated: 2024-11-02

pd 169316 and Glioblastoma

pd 169316 has been researched along with Glioblastoma in 1 studies

2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole: p38 MAP kinase inhibitor

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline treatment also increased GDNF mRNA expression in rat astrocytes."1.31Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells. ( Hisaoka, K; Koda, T; Miyata, M; Morinobu, S; Nishida, A; Ohta, M; Yamawaki, S; Zensho, H, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hisaoka, K1
Nishida, A1
Koda, T1
Miyata, M1
Zensho, H1
Morinobu, S1
Ohta, M1
Yamawaki, S1

Other Studies

1 other study available for pd 169316 and Glioblastoma

ArticleYear
Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells.
    Journal of neurochemistry, 2001, Volume: 79, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Astrocytes; Butadienes; Cell Line; Cells, Cultured; C

2001