ubiquinone-q2 has been researched along with Glioblastoma* in 1 studies
1 other study(ies) available for ubiquinone-q2 and Glioblastoma
| Article | Year |
|---|---|
Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide.
To investigate how the modulation of the oxidative balance affects cytotoxic therapies in glioblastoma, in vitro.. Human glioblastoma U251 and T98 cells and normal astrocytes C8D1A were loaded with coenzyme Q10 (CoQ). Mitochondrial superoxide ion (O. CoQ did not affect oxygen consumption but reduced the level of O. CoQ acts as sensitizer for cytotoxic therapies, disarming GBM cells, but not normal astrocytes, against further pro-oxidant injuries, being potentially useful in clinical practice for this fatal pathology. Topics: Antioxidants; Apoptosis; Brain Neoplasms; Dacarbazine; DNA Damage; Glioblastoma; Humans; Hydrogen Peroxide; Mitochondria; Oxidative Stress; Oxygen Consumption; Radiation Tolerance; Reactive Oxygen Species; Temozolomide; Tumor Cells, Cultured; Ubiquinone | 2018 |