amphetamine has been researched along with Glioblastoma in 1 studies
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.
amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combating brain tumors (glioblastoma multiforme or GBM) is a formidable challenge because of the existence of blood-brain barrier (BBB), a tight cellular junction that separates the central nervous system (CNS) and systemic circulation." | 5.56 | Amphetamine decorated cationic lipid nanoparticles cross the blood-brain barrier: therapeutic promise for combating glioblastoma. ( Banerjee, R; Chaudhuri, A; Jaggarapu, MMCS; Madhusudana, K; Moku, G; Ramkrishna, S; Saha, S; Shankar, G; Srinivas, R; Yakati, V, 2020) |
| "Combating brain tumors (glioblastoma multiforme or GBM) is a formidable challenge because of the existence of blood-brain barrier (BBB), a tight cellular junction that separates the central nervous system (CNS) and systemic circulation." | 1.56 | Amphetamine decorated cationic lipid nanoparticles cross the blood-brain barrier: therapeutic promise for combating glioblastoma. ( Banerjee, R; Chaudhuri, A; Jaggarapu, MMCS; Madhusudana, K; Moku, G; Ramkrishna, S; Saha, S; Shankar, G; Srinivas, R; Yakati, V, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saha, S | 1 |
| Yakati, V | 1 |
| Shankar, G | 1 |
| Jaggarapu, MMCS | 1 |
| Moku, G | 1 |
| Madhusudana, K | 1 |
| Banerjee, R | 1 |
| Ramkrishna, S | 1 |
| Srinivas, R | 1 |
| Chaudhuri, A | 1 |
1 other study available for amphetamine and Glioblastoma
| Article | Year |
|---|---|
Amphetamine decorated cationic lipid nanoparticles cross the blood-brain barrier: therapeutic promise for combating glioblastoma.
Topics: Amphetamine; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cations; Cell Pro | 2020 |