benzyl isothiocyanate has been researched along with Glioblastoma in 3 studies
benzyl isothiocyanate: inhibits carcinogen-induced neoplasia; structure in Negwer, 5th ed, #715; also promotes urinary bladder carcinoma
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzyl isothiocyanate (BITC), a member of isothiocyanates (ITCs), has been shown to induce cell death in many human cancer cells, but there is no further report to show BITC suppresses glioblastoma multiforme cells in vivo." | 7.88 | Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo. ( Chung, JG; Fan, MJ; Hsu, FT; Lien, JC; Lin, CC; Lin, JJ; Ma, YS; Peng, SF, 2018) |
| "Benzyl isothiocyanate (BITC), a member of isothiocyanates (ITCs), has been shown to induce cell death in many human cancer cells, but there is no further report to show BITC suppresses glioblastoma multiforme cells in vivo." | 3.88 | Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo. ( Chung, JG; Fan, MJ; Hsu, FT; Lien, JC; Lin, CC; Lin, JJ; Ma, YS; Peng, SF, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shang, HS | 1 |
| Shih, YL | 1 |
| Lu, TJ | 1 |
| Lee, CH | 1 |
| Hsueh, SC | 1 |
| Chou, YC | 1 |
| Lu, HF | 1 |
| Liao, NC | 1 |
| Chung, JG | 3 |
| Ma, YS | 1 |
| Lin, JJ | 2 |
| Lin, CC | 1 |
| Lien, JC | 1 |
| Peng, SF | 1 |
| Fan, MJ | 1 |
| Hsu, FT | 1 |
| Tang, NY | 1 |
| Chueh, FS | 1 |
| Yu, CC | 1 |
| Liao, CL | 1 |
| Hsia, TC | 1 |
| Wu, KC | 1 |
| Liu, HC | 1 |
| Lu, KW | 1 |
3 other studies available for benzyl isothiocyanate and Glioblastoma
| Article | Year |
|---|---|
Benzyl isothiocyanate (BITC) induces apoptosis of GBM 8401 human brain glioblastoma multiforms cells via activation of caspase-8/Bid and the reactive oxygen species-dependent mitochondrial pathway.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibito | 2016 |
Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isothiocyanates; | 2018 |
Benzyl isothiocyanate alters the gene expression with cell cycle regulation and cell death in human brain glioblastoma GBM 8401 cells.
Topics: Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Damage; Extracellular M | 2016 |