phenylacetic acid has been researched along with Glioblastoma in 2 studies
phenylacetic acid : A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One of six patients with glioblastoma multiforme, whose steroid dosage has remained unchanged for the duration of therapy, has sustained functional improvement for more than 9 months." | 2.67 | A phase I and pharmacokinetic study of intravenous phenylacetate in patients with cancer. ( Cooper, MR; Figg, WD; Headlee, DJ; McCall, NA; Samid, D; Sartor, AO; Thibault, A; Tompkins, AC; Venzon, DJ; Weinberger, MS, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thibault, A | 1 |
| Cooper, MR | 1 |
| Figg, WD | 1 |
| Venzon, DJ | 1 |
| Sartor, AO | 1 |
| Tompkins, AC | 1 |
| Weinberger, MS | 1 |
| Headlee, DJ | 1 |
| McCall, NA | 1 |
| Samid, D | 1 |
| Ozawa, T | 1 |
| Lu, RM | 1 |
| Hu, LJ | 1 |
| Lamborn, KR | 1 |
| Prados, MD | 1 |
| Deen, DF | 1 |
1 trial available for phenylacetic acid and Glioblastoma
| Article | Year |
|---|---|
A phase I and pharmacokinetic study of intravenous phenylacetate in patients with cancer.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Administration Schedule; Female; Glioblast | 1994 |
1 other study available for phenylacetic acid and Glioblastoma
| Article | Year |
|---|---|
Radiopotentiation of human brain tumor cells by sodium phenylacetate.
Topics: Brain Neoplasms; Cell Division; Cell Hypoxia; Cell Survival; Glioblastoma; Humans; Medulloblastoma; | 1999 |