trapidil has been researched along with Glioblastoma in 3 studies
Trapidil: A coronary vasodilator agent.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of trapidil on platelet-derived growth factor (PDGF)-associated growth of glioblastoma cells were studied." | 3.68 | Antiproliferative effect of trapidil on PDGF-associated growth of human glioma cell lines in vitro. ( Abe, H; Aida, T; Hosokawa, M; Kobayashi, H; Sawamura, Y; Tada, M, 1991) |
| "Trapidil and suramin inhibit this growth factor-stimulated glioma cell growth, but the mechanisms are not fully understood." | 1.29 | Effects of trapidil and suramin on growth factor-induced calcium response and tyrosine phosphorylation in human glioma cells. ( Bando, K; Kannuki, S; Matsumoto, K; Rokutan, K; Shouno, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bando, K | 1 |
| Kannuki, S | 1 |
| Rokutan, K | 1 |
| Shouno, M | 1 |
| Matsumoto, K | 1 |
| Pollack, IF | 1 |
| Randall, MS | 1 |
| Kristofik, MP | 1 |
| Kelly, RH | 1 |
| Selker, RG | 1 |
| Vertosick, FT | 1 |
| Tada, M | 1 |
| Aida, T | 1 |
| Hosokawa, M | 1 |
| Kobayashi, H | 1 |
| Sawamura, Y | 1 |
| Abe, H | 1 |
3 other studies available for trapidil and Glioblastoma
| Article | Year |
|---|---|
Effects of trapidil and suramin on growth factor-induced calcium response and tyrosine phosphorylation in human glioma cells.
Topics: Antineoplastic Agents; Calcium; Cell Division; Epidermal Growth Factor; Glioblastoma; Humans; Phosph | 1995 |
Response of low-passage human malignant gliomas in vitro to stimulation and selective inhibition of growth factor-mediated pathways.
Topics: Antibodies; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioblastoma; Growth I | 1991 |
Antiproliferative effect of trapidil on PDGF-associated growth of human glioma cell lines in vitro.
Topics: Animals; Antibodies, Monoclonal; Biological Assay; Brain Neoplasms; Cell Division; Cells, Cultured; | 1991 |