Page last updated: 2024-08-23

4-boronophenylalanine and Glioblastoma

4-boronophenylalanine has been researched along with Glioblastoma in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (37.50)	18.2507
2000's	8 (33.33)	29.6817
2010's	6 (25.00)	24.3611
2020's	1 (4.17)	2.80

Authors

Authors	Studies
Fukuda, H; Hiratsuka, J	1
Anbai, A; Harada, T; Hashimoto, M; Hirose, K; Sato, M; Takai, Y; Wada, Y; Watanabe, T	1
Arai, Y; Fujii, H; Honda, N; Itami, J; Kawai, K; Kurihara, H; Ohe, K; Yoshimoto, M	1
Moss, RL; Sauerwein, WA; Wittig, A	1
Kinashi, Y; Kitajima, E; Kubota, Y; Okayasu, R; Okumura, K; Ono, K; Takahashi, S	1
Ahmad, T; Barth, RF; Chandra, S; Kabalka, GW	1
Kumada, H; Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Tsurubuchi, T; Yamamoto, T	1
Doi, A; Hiramatsu, R; Iida, K; Imahori, Y; Kawabata, S; Kirihata, M; Kumada, H; Kuroda, Y; Kuroiwa, T; Maruhashi, A; Masunaga, S; Michiue, H; Miyata, S; Miyatake, S; Nonoguchi, N; Ono, K; Sakurai, Y; Suzuki, M; Yokoyama, K	1
Cheng, X; Guo, G; Jiang, X; Mao, X; Wang, P; Zhang, W; Zhang, X; Zhen, H	1
Chandra, S; Coderre, JA; Kabalka, GW; Lorey, DR; Smith, DR	1
Bergenheim, AT; Capala, J; Henriksson, R; Roslin, M	1
Brun, A; H-Stenstam, B; Pellettieri, L; Rezaei, A; Sköld, K	1
Barth, RF; Chandra, S; Lorey, DR; Tjarks, W	1
Flam, F	1
Bergland, R; Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD; Liu, HB; Slatkin, DN	1
Buonocore, E; Dyke, JP; Hübner, KF; Kabalka, GW; Longford, CP; Reddy, NK; Reid, WS; Roberts, TG; Smith, GT	1
Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Gebbers, JO; Joel, DD; Micca, PL; Nawrocky, MM; Peress, NS; Shady, M; Slatkin, DN	1
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S	1
Bergland, RM; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD	1
Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Iwai, J; Joel, DD; Liu, HB; Wielopolski, L	1
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM	1
Aziz, T; Capala, J; Chanana, A; Diaz, A; Peress, NS	1
Busse, PM; Kiger, WS; Palmer, MR; Riley, KJ; Zamenhof, RG	1
Barth, RF; Fairchild, RG; Soloway, AH	1

Reviews

1 review(s) available for 4-boronophenylalanine and Glioblastoma

Article	Year
Pharmacokinetics of Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 166 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography	2020

Trials

4 trial(s) available for 4-boronophenylalanine and Glioblastoma

Article	Year
Neuropathological postmortem evaluation of BNCT for GBM. Acta neurologica Scandinavica, 2007, Volume: 116, Issue:3 Topics: Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Follow-Up Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiotherapy Dosage; Treatment Outcome	2007
Boron neutron capture therapy for glioblastoma multiforme using p-boronophenylalanine and epithermal neutrons: trial design and early clinical results. Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2 Topics: Adult; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neutrons; Nuclear Reactors; Phenylalanine; Tissue Distribution	1997
Boron neutron-capture therapy (BNCT) for glioblastoma multiforme (GBM) using the epithermal neutron beam at the Brookhaven National Laboratory. International journal of radiation oncology, biology, physics, 1998, Mar-01, Volume: 40, Issue:4 Topics: Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Feasibility Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Outcome	1998
A pharmacokinetic model for the concentration of 10B in blood after boronophenylalanine-fructose administration in humans. Radiation research, 2001, Volume: 155, Issue:4 Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Models, Biological; Phenylalanine; Skin Neoplasms	2001

Other Studies

19 other study(ies) available for 4-boronophenylalanine and Glioblastoma

Article	Year
Impact of oxygen status on 10B-BPA uptake into human glioblastoma cells, referring to significance in boron neutron capture therapy. Journal of radiation research, 2018, Mar-01, Volume: 59, Issue:2 Topics: Adaptor Proteins, Signal Transducing; Boron Compounds; Boron Neutron Capture Therapy; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Large Neutral Amino Acid-Transporter 1; Oxygen; Phenylalanine; RNA, Messenger	2018
Predominant contribution of L-type amino acid transporter to 4-borono-2-(18)F-fluoro-phenylalanine uptake in human glioblastoma cells. Nuclear medicine and biology, 2013, Volume: 40, Issue:5 Topics: Amino Acid Transport Systems; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography	2013
Glioblastoma, brain metastases and soft tissue sarcoma of extremities: candidate tumors for BNCT. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Animals; Borohydrides; Boron Compounds; Brain Neoplasms; Cell Line, Tumor; Extremities; Glioblastoma; Humans; Male; Mice; Mice, Nude; Phenylalanine; Radiotherapy Dosage; Sarcoma; Sulfhydryl Compounds; Tissue Distribution	2014
Dose-rate effect was observed in T98G glioma cells following BNCT. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Radiation; Glioblastoma; Humans; Phenylalanine; Radiotherapy Dosage; Treatment Outcome	2014
Quantitative evaluation of boron neutron capture therapy (BNCT) drugs for boron delivery and retention at subcellular-scale resolution in human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS). Journal of microscopy, 2014, Volume: 254, Issue:3 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Calcium; Cell Line, Tumor; Cell Tracking; Glioblastoma; Humans; Intracellular Space; Isotopes; Microscopy, Confocal; Phenylalanine; Potassium; Sodium; Spectrometry, Mass, Secondary Ion; Time Factors	2014
Dose distribution and clinical response of glioblastoma treated with boron neutron capture therapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Adult; Aged; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Photons; Radiotherapy Dosage; Retrospective Studies; Sulfhydryl Compounds; Survival Rate; Treatment Failure	2009
Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Protocols; Combined Modality Therapy; Glioblastoma; Humans; Japan; Phenylalanine; Prognosis; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Survival Rate	2009
Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax. BMC cancer, 2010, Dec-02, Volume: 10 Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Flow Cytometry; Gamma Rays; Glioblastoma; Humans; Microscopy, Electron, Transmission; Neutrons; Phenylalanine; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Time Factors	2010
Imaging of fluorine and boron from fluorinated boronophenylalanine in the same cell at organelle resolution by correlative ion microscopy and confocal laser scanning microscopy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8 Topics: Boron; Boron Compounds; Brain Neoplasms; Fluorine; Glioblastoma; Humans; Image Processing, Computer-Assisted; Ions; Microscopy, Confocal; Mitochondria; Models, Chemical; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tomography, Emission-Computed; Tumor Cells, Cultured	2002
Distribution of BPA and metabolic assessment in glioblastoma patients during BNCT treatment: a microdialysis study. Journal of neuro-oncology, 2005, Volume: 71, Issue:3 Topics: Blood Glucose; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Microdialysis; Phenylalanine; Radiation-Sensitizing Agents	2005
Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS). Journal of microscopy, 2008, Volume: 229, Issue:Pt 1 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Glioblastoma; Humans; Interphase; Mitosis; Phenylalanine; Spectrometry, Mass, Secondary Ion	2008
Cancer treatment. Will history repeat for boron capture therapy? Science (New York, N.Y.), 1994, Jul-22, Volume: 265, Issue:5171 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Trials as Topic; Glioblastoma; Humans; Japan; Phenylalanine; Radiation-Sensitizing Agents; United States	1994
Evaluation of fluorine-18-BPA-fructose for boron neutron capture treatment planning. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:11 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Fructose; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed	1997
Biodistribution of boronophenylalanine in patients with glioblastoma multiforme: boron concentration correlates with tumor cellularity. Radiation research, 1998, Volume: 149, Issue:2 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Glioblastoma; Humans; Phenylalanine; Tissue Distribution	1998
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:2 Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed	1998
Biodistribution of p-boronophenylalanine in patients with glioblastoma multiforme for use in boron neutron capture therapy. Neurosurgery, 1998, Volume: 42, Issue:3 Topics: Boron Compounds; Brain; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Injections, Intravenous; Neutron Capture Therapy; Osmolar Concentration; Phenylalanine; Radiation-Sensitizing Agents; Scalp; Tissue Distribution	1998
Effect of dose and infusion time on the delivery of p-boronophenylalanine for neutron capture therapy. Journal of neuro-oncology, 1999, Volume: 41, Issue:3 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Gliosarcoma; Infusions, Intravenous; Metabolic Clearance Rate; Phenylalanine; Radiation-Sensitizing Agents; Rats; Tissue Distribution; Tumor Cells, Cultured	1999
Postmortem neuropathological features secondary to boron neutron capture therapy for glioblastoma multiforme. Journal of neuropathology and experimental neurology, 2000, Volume: 59, Issue:1 Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Female; Glioblastoma; Humans; Lewy Bodies; Male; Middle Aged; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Phenylalanine; Radiation-Sensitizing Agents	2000
Boron neutron capture therapy for cancer. Scientific American, 1990, Volume: 263, Issue:4 Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage	1990