Page last updated: 2024-11-03

ritanserin and Glioblastoma

ritanserin has been researched along with Glioblastoma in 2 studies

Ritanserin: A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The drug also improves the subjective quality of sleep and decreases portal pressure.
ritanserin : A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olmez, I1
Love, S1
Xiao, A1
Manigat, L1
Randolph, P1
McKenna, BD1
Neal, BP1
Boroda, S1
Li, M1
Brenneman, B1
Abounader, R1
Floyd, D1
Lee, J1
Nakano, I1
Godlewski, J1
Bronisz, A1
Sulman, EP1
Mayo, M1
Gioeli, D1
Weber, M1
Harris, TE1
Purow, B1
Audia, A1
Bhat, KP1

Other Studies

2 other studies available for ritanserin and Glioblastoma

ArticleYear
Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Diacylglycerol Kinase; Female; Glioblastoma; Humans; Mic

2018
Ritanserin, a novel agent targeting the mesenchymal subtype of glioblastomas.
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Adult; Diacylglycerol Kinase; Glioblastoma; Humans; Piperidines; Ritanserin

2018