| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID496950 | Antiproliferative activity against human KBV1 cells overexpressing MDR1 after 72 hrs by Alamar blue assay in presence of zosuquidar | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496943 | Antiproliferative activity against human BxPC3 cells after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496948 | Drug resistant ratio of EC50 for human KBV1 cells overexpressing MDR1 to EC50 for KB3-1 cells | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496947 | Antiproliferative activity against human KBV1 cells overexpressing MDR1 after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496949 | Antiproliferative activity against human KB3-1 cells after 72 hrs by Alamar blue assay in presence of zosuquidar | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496945 | Antiproliferative activity against human NCI-H1299 cells after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID465253 | Competitive inhibition of affinity bead (R)-2-Amino-N-{2-[2-(2-amino-ethoxy)-ethoxy]-ethyl}-3-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-propionamide binding to KSP in human HCT116 cells at 10 umol/L pretreated for 3 hrs by Western blot analysis | 2010 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 20, Issue:5
| Biochemical analysis of cellular target of S-trityl-L-cysteine derivatives using affinity matrix. |
| AID300454 | Inhibition of Eg5 ATPase activity expressed in Escherichia coli after 12 hrs | 2007 | Bioorganic & medicinal chemistry, Oct-01, Volume: 15, Issue:19
| New chemical tools for investigating human mitotic kinesin Eg5. |
| AID496946 | Antiproliferative activity against human KB3-1 cells after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496941 | Antiproliferative activity against human HCT116 cells after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID496944 | Antiproliferative activity against human K562 cells after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| AID1610651 | Inhibition of recombinant human His-tagged Eg5 (1 to 368 residues) assessed as reduction in ATPase activity by Bradford reagent based assay | | | |
| AID1405697 | Inhibition of human Eg5 | 2018 | European journal of medicinal chemistry, Aug-05, Volume: 156 | Synthesis and anticancer activity of new dihydropyrimidinone derivatives. |
| AID496942 | Antiproliferative activity against human hTERT-HME1 cells after 72 hrs by Alamar blue assay | 2010 | Journal of medicinal chemistry, Aug-12, Volume: 53, Issue:15
| Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |