pentoxifylline has been researched along with Glioblastoma in 3 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six human glioblastoma cell lines were tested for the effect of pentoxifylline treatment at maximum G2/M block on the basis of cell survival, mitotic activity, and micronucleus formation after exposure to gamma radiation." | 3.79 | In vitro radiosensitization by pentoxifylline does not depend on p53 status. ( Akudugu, JM; Böhm, LJ; Serafin, AM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akudugu, JM | 1 |
| Serafin, AM | 1 |
| Böhm, LJ | 1 |
| Sperduto, PW | 1 |
| Song, CW | 1 |
| Levitt, SH | 1 |
| Stewart, DJ | 1 |
| Dahrouge, S | 1 |
| Agboola, O | 1 |
| Girard, A | 1 |
1 trial available for pentoxifylline and Glioblastoma
| Article | Year |
|---|---|
Cranial radiation and concomitant cisplatin and mitomycin-C plus resistance modulators for malignant gliomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Brain Neoplasms; Cisplat | 1997 |
2 other studies available for pentoxifylline and Glioblastoma
| Article | Year |
|---|---|
In vitro radiosensitization by pentoxifylline does not depend on p53 status.
Topics: Cell Line, Tumor; Cell Survival; Glioblastoma; Humans; Pentoxifylline; Radiation Tolerance; Radiatio | 2013 |
The in vitro radiosensitization of human glioblastoma with pentoxifylline.
Topics: Cell Survival; Glioblastoma; Humans; Pentoxifylline; Radiation-Protective Agents; Radiation-Sensitiz | 1993 |