cytosine has been researched along with Glioblastoma in 9 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we show that TET1-mediated production of 5-hydroxymethylcytosine (5hmC) is required for the tumorigenicity of glioblastoma cells." | 7.80 | 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex. ( Akiyama, T; Ino, Y; Katou, Y; Koyama-Nasu, R; Kozuka-Hata, H; Masuda, K; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Ogawa, H; Oyama, M; Saito, N; Sakaguchi, Y; Sato, T; Shirahige, K; Suzuki, T; Takai, H; Todo, T; Toyoshima, C, 2014) |
| " Here, we show that TET1-mediated production of 5-hydroxymethylcytosine (5hmC) is required for the tumorigenicity of glioblastoma cells." | 3.80 | 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex. ( Akiyama, T; Ino, Y; Katou, Y; Koyama-Nasu, R; Kozuka-Hata, H; Masuda, K; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Ogawa, H; Oyama, M; Saito, N; Sakaguchi, Y; Sato, T; Shirahige, K; Suzuki, T; Takai, H; Todo, T; Toyoshima, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cheray, M | 1 |
| Etcheverry, A | 1 |
| Jacques, C | 1 |
| Pacaud, R | 1 |
| Bougras-Cartron, G | 1 |
| Aubry, M | 1 |
| Denoual, F | 1 |
| Peterlongo, P | 1 |
| Nadaradjane, A | 1 |
| Briand, J | 1 |
| Akcha, F | 1 |
| Heymann, D | 1 |
| Vallette, FM | 1 |
| Mosser, J | 1 |
| Ory, B | 1 |
| Cartron, PF | 1 |
| Galardi, S | 1 |
| Michienzi, A | 1 |
| Ciafrè, SA | 1 |
| Sahin, Z | 1 |
| Biltekin, SN | 1 |
| Yurttas, L | 1 |
| Berk, B | 1 |
| Özhan, Y | 1 |
| Sipahi, H | 1 |
| Gao, ZG | 1 |
| Jacobson, KA | 1 |
| Demirayak, Ş | 1 |
| Kazlauskas, A | 1 |
| Darinskas, A | 1 |
| Meškys, R | 1 |
| Tamašauskas, A | 1 |
| Urbonavičius, J | 1 |
| Hadaczek, P | 1 |
| Ozawa, T | 1 |
| Soroceanu, L | 1 |
| Yoshida, Y | 1 |
| Matlaf, L | 1 |
| Singer, E | 1 |
| Fiallos, E | 1 |
| James, CD | 1 |
| Cobbs, CS | 1 |
| Moen, EL | 1 |
| Stark, AL | 1 |
| Zhang, W | 1 |
| Dolan, ME | 1 |
| Godley, LA | 1 |
| Takai, H | 1 |
| Masuda, K | 1 |
| Sato, T | 1 |
| Sakaguchi, Y | 1 |
| Suzuki, T | 2 |
| Koyama-Nasu, R | 1 |
| Nasu-Nishimura, Y | 1 |
| Katou, Y | 1 |
| Ogawa, H | 1 |
| Morishita, Y | 1 |
| Kozuka-Hata, H | 1 |
| Oyama, M | 1 |
| Todo, T | 1 |
| Ino, Y | 1 |
| Mukasa, A | 1 |
| Saito, N | 1 |
| Toyoshima, C | 1 |
| Shirahige, K | 1 |
| Akiyama, T | 1 |
| Kraus, TF | 1 |
| Kolck, G | 1 |
| Greiner, A | 1 |
| Schierl, K | 1 |
| Guibourt, V | 1 |
| Kretzschmar, HA | 1 |
| Müller, T | 1 |
| Gessi, M | 1 |
| Waha, A | 2 |
| Isselstein, LJ | 1 |
| Luxen, D | 1 |
| Freihoff, D | 1 |
| Freihoff, J | 1 |
| Becker, A | 1 |
| Simon, M | 1 |
| Hammes, J | 1 |
| Denkhaus, D | 1 |
| zur Mühlen, A | 1 |
| Pietsch, T | 1 |
1 review available for cytosine and Glioblastoma
| Article | Year |
|---|---|
Insights into the Regulatory Role of m
Topics: Adenosine; Brain Neoplasms; Cytosine; Epigenesis, Genetic; Gene Expression Profiling; Gene Expressio | 2020 |
8 other studies available for cytosine and Glioblastoma
| Article | Year |
|---|---|
Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme.
Topics: Animals; Apoptosis; Argonaute Proteins; Biomarkers, Tumor; Cell Proliferation; Cytosine; DNA (Cytosi | 2020 |
Novel cyanothiouracil and cyanothiocytosine derivatives as concentration-dependent selective inhibitors of U87MG glioblastomas: Adenosine receptor binding and potent PDE4 inhibition.
Topics: Antineoplastic Agents; Binding Sites; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclic Nuc | 2021 |
Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Caco-2 Cells; Cell Line, | 2019 |
Cidofovir: a novel antitumor agent for glioblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cidofov | 2013 |
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
Topics: Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; CpG Islands; Cytosine; Dacarbazine | 2014 |
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
Topics: 5-Methylcytosine; Acetylation; Brain Neoplasms; Carcinogenesis; Chromatin; Cytosine; DNA-Binding Pro | 2014 |
Loss of 5-hydroxymethylcytosine and intratumoral heterogeneity as an epigenomic hallmark of glioblastoma.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Cytosine; DNA Methylation; DNA Modification Methyl | 2015 |
Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas.
Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cytosine; Dioxygenases; DNA Methy | 2012 |