phloretin has been researched along with Glioblastoma in 2 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phloretin is a type of dihydrochalcone that is primarily found in apples and has been reported to possess various potent biological activities, such as anticancer, antioxidant and anti-inflammatory effects." | 1.72 | Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation. ( Fan, C; Teng, J; Tian, Y; Zhang, Y; Zhao, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, C | 2 |
| Zhang, Y | 1 |
| Tian, Y | 1 |
| Zhao, X | 1 |
| Teng, J | 1 |
| Liu, Y | 1 |
| Pu, L | 1 |
| Wei, C | 1 |
| Jin, H | 1 |
| Teng, Y | 1 |
| Zhao, M | 1 |
| Yu, AC | 1 |
| Jiang, F | 1 |
| Shu, J | 1 |
| Li, F | 1 |
| Peng, Q | 1 |
| Kong, J | 1 |
| Pan, B | 1 |
| Zheng, L | 1 |
| Huang, Y | 1 |
2 other studies available for phloretin and Glioblastoma
| Article | Year |
|---|---|
Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation.
Topics: Apoptosis; Autophagy; Beclin-1; Cell Line, Tumor; Glioblastoma; Humans; Neuroblastoma; Phloretin; Pr | 2022 |
Phloretin induces cell cycle arrest and apoptosis of human glioblastoma cells through the generation of reactive oxygen species.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; | 2016 |