theophylline has been researched along with Glioblastoma in 4 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rolipram-treated A172 or U87MG cell survival was lower in the presence of forskolin, adenylate cyclase activator, than that in its absence." | 1.38 | Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways. ( Kim, HM; Lee, GH; Lee, JW; Lee, MS; Moon, EY, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moon, EY | 1 |
| Lee, GH | 1 |
| Lee, MS | 1 |
| Kim, HM | 1 |
| Lee, JW | 1 |
| Caciagli, F | 1 |
| Ciccarelli, R | 1 |
| Ciancetta, S | 1 |
| Di Iorio, P | 1 |
| Caciagli, P | 1 |
| Newburgh, RW | 1 |
| Rosenberg, RN | 1 |
| Hidaka, H | 1 |
| Shibuya, M | 1 |
4 other studies available for theophylline and Glioblastoma
| Article | Year |
|---|---|
Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways.
Topics: 1-Methyl-3-isobutylxanthine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neopla | 2012 |
Adenosine--norepinephrine interactions on cyclic AMP generating system in human tumoral brain slices.
Topics: Adenosine; Adult; Aged; Brain Neoplasms; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; | 1982 |
Effect of norepinephrine on glucose metabolism in glioblastoma and neuroblastoma cells in cell culture.
Topics: Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Clone Cells; Cyclic AMP; Depression, | 1972 |
A new assay of cyclic nucleotide phosphodiesterase; its application to human serum.
Topics: Adult; Animals; Brain; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Glioblastoma; Humans; H | 1974 |