nicardipine has been researched along with Glioblastoma in 5 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 Gy) combined with radiosensitizing agents." | 2.67 | Radiation therapy combined with radiosensitizing agents for cerebral glioblastoma in adults. ( Asai, A; Fujimaki, T; Matsutani, M; Nagashima, T; Nakamura, M; Nakamura, O; Tanaka, H; Tanaka, Y; Ueki, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Yu, J | 1 |
| Pan, H | 1 |
| Hu, P | 1 |
| Hao, Y | 1 |
| Cai, W | 1 |
| Zhu, H | 1 |
| Yu, AD | 1 |
| Xie, X | 1 |
| Ma, D | 1 |
| Yuan, J | 1 |
| Zmuda, F | 1 |
| Malviya, G | 1 |
| Blair, A | 1 |
| Boyd, M | 1 |
| Chalmers, AJ | 1 |
| Sutherland, A | 1 |
| Pimlott, SL | 1 |
| Huang, CX | 1 |
| Chen, B | 2 |
| Zhang, YF | 1 |
| Matsutani, M | 1 |
| Nakamura, O | 1 |
| Nakamura, M | 1 |
| Nagashima, T | 1 |
| Asai, A | 1 |
| Fujimaki, T | 1 |
| Tanaka, H | 1 |
| Ueki, K | 1 |
| Tanaka, Y | 1 |
| Huang, C | 1 |
| Hu, S | 1 |
1 trial available for nicardipine and Glioblastoma
| Article | Year |
|---|---|
Radiation therapy combined with radiosensitizing agents for cerebral glioblastoma in adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne | 1994 |
4 other studies available for nicardipine and Glioblastoma
| Article | Year |
|---|---|
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; G | 2007 |
Synthesis and Evaluation of a Radioiodinated Tracer with Specificity for Poly(ADP-ribose) Polymerase-1 (PARP-1) in Vivo.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Mice | 2015 |
[Growth inhibition of epidermal growth factor-stimulated human glioblastoma cells by nicardipine in vito].
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Division; Culture Media, Serum-Free; Epidermal Growth F | 2001 |
Growth inhibition of epidermal growth factor-stimulated human glioblastoma cells by nicardipine in vitro.
Topics: Calcium Channel Blockers; Cell Division; Dose-Response Relationship, Drug; Epidermal Growth Factor; | 2001 |