racemetirosine has been researched along with Glioblastoma in 3 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To develop a valid treatment strategy for recurrent high-grade gliomas using stereotactic hypofractionated reirradiation based on biologic imaging and temozolomide." | 3.73 | Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy. ( Franz, M; Grosu, AL; Gumprecht, H; Molls, M; Nieder, C; Piert, M; Schwaiger, M; Stärk, S; Thamm, R; Weber, WA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riemann, B | 1 |
| Papke, K | 1 |
| Hoess, N | 1 |
| Kuwert, T | 2 |
| Weckesser, M | 1 |
| Matheja, P | 2 |
| Wassmann, H | 2 |
| Heindel, W | 1 |
| Schober, O | 2 |
| Grosu, AL | 1 |
| Weber, WA | 1 |
| Franz, M | 1 |
| Stärk, S | 1 |
| Piert, M | 1 |
| Thamm, R | 1 |
| Gumprecht, H | 1 |
| Schwaiger, M | 1 |
| Molls, M | 1 |
| Nieder, C | 1 |
| Woesler, B | 1 |
| Morgenroth, C | 1 |
| Palkovic, S | 1 |
| Schäfers, M | 1 |
| Vollet, B | 1 |
| Schäfers, K | 1 |
| Lerch, H | 1 |
| Brandau, W | 1 |
| Samnick, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amino-acid PET Versus MRI Guided Re-irradiation in Patients With Recurrent Glioblastoma Multiforme - a Randomised Phase II Trial[NCT01252459] | Phase 2 | 200 participants (Anticipated) | Interventional | 2011-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for racemetirosine and Glioblastoma
| Article | Year |
|---|---|
Noninvasive grading of untreated gliomas: a comparative study of MR imaging and 3-(iodine 123)-L-alpha-methyltyrosine SPECT.
Topics: Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Astrocytoma; Biopsy; Brain; Brain Neoplasms; F | 2002 |
Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy.
Topics: Adult; Aged; alpha-Methyltyrosine; Analysis of Variance; Antineoplastic Agents, Alkylating; Astrocyt | 2005 |
Non-invasive grading of primary brain tumours: results of a comparative study between SPET with 123I-alpha-methyl tyrosine and PET with 18F-deoxyglucose.
Topics: Adult; Aged; alpha-Methyltyrosine; Amino Acids; Astrocytoma; Brain; Brain Neoplasms; Deoxyglucose; E | 1997 |