Page last updated: 2024-12-05
2-(4-fluorophenyl)acetic acid
Description
2-(4-Fluorophenyl)acetic acid, also known as 4-fluoro-phenylacetic acid, is a synthetic organic compound that has been studied for its potential pharmacological properties. It is an analogue of phenylacetic acid, with a fluorine atom substituted at the para position of the phenyl ring. The compound has been shown to exhibit various biological activities, including anti-inflammatory, analgesic, and anticonvulsant effects. It has also been investigated for its potential use in treating conditions such as cancer and Alzheimer's disease. The synthesis of 2-(4-fluorophenyl)acetic acid typically involves the reaction of 4-fluorophenylacetonitrile with a strong acid, such as hydrochloric acid, followed by hydrolysis. The compound's importance stems from its unique chemical structure and its ability to interact with various biological targets. Research on 2-(4-fluorophenyl)acetic acid focuses on understanding its mechanisms of action, exploring its therapeutic potential, and optimizing its chemical properties for drug development. '
2-(4-fluorophenyl)acetic acid: a positron emitting tumor imaging agent; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 9837 |
| SCHEMBL ID | 104746 |
| MeSH ID | M0425162 |
Synonyms (54)
| Synonym |
|---|
| STK499017 |
| p-fluorophenylacetic acid |
| ba 2821 |
| 405-50-5 |
| acetic acid, (p-fluorophenyl)- |
| nsc-402 |
| (p-fluorophenyl)acetic acid |
| benzeneacetic acid, 4-fluoro- |
| (4-fluorophenyl)acetic acid |
| nsc402 |
| 4-fluorophenylacetic acid, 98% |
| 4-fluorophenylacetic acid |
| MAYBRIDGE1_006666 |
| AC-10975 |
| HMS560G22 |
| 2-(4-fluorophenyl)acetic acid |
| mgkpfalcndrsqd-uhfffaoysa- |
| inchi=1/c8h7fo2/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4h,5h2,(h,10,11) |
| F0206 |
| AKOS000119591 |
| AH-034/32462009 |
| unii-s5yjv7caz1 |
| nsc 402 |
| s5yjv7caz1 , |
| ai3-52627 |
| einecs 206-972-4 |
| A825162 |
| 2-(4-fluorophenyl)-acetic acid |
| BP-20574 |
| FT-0601465 |
| AM20060020 |
| SCHEMBL104746 |
| BH-0409 |
| p-fluorophenylacetic acid [mi] |
| fluorophenylacetic acid, p- |
| 4-fluorobenzeneacetic acid |
| (4-fluoro-phenyl)-acetic acid |
| 4-fluoro phenylacetic acid |
| p-fluorophenyl acetic acid |
| 4-fluorophenyl-acetic acid |
| 4-fluoro phenyl acetic acid |
| 4-fluorophenyl acetic acid |
| 4-fluoro-phenyl-acetic acid |
| DTXSID0059956 |
| W-106345 |
| mfcd00004343 |
| F2191-0056 |
| CS-W001955 |
| SY001347 |
| Q27288702 |
| n-boc-(r)-2-amino-3-hydroxy-3-methylbutanoicacid |
| EN300-20216 |
| PD119085 |
| Z104477312 |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.64
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.64 (24.57) | | Research Supply Index | 1.95 (2.92) | | Research Growth Index | 4.59 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |