Page last updated: 2024-10-18

dimethyl sulfoxide and Glioblastoma

dimethyl sulfoxide has been researched along with Glioblastoma in 10 studies

Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
" Treatment of human melanoma cells with recombinant fibroblast interferon (IFN-beta) and the protein kinase C activator mezerein (MEZ) results in an irreversible loss in growth potential, suppression of tumorigenic properties and induction of terminal cell differentiation."3.71Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. ( Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N, 2001)
"Ruthenium compounds have been actively studied as metallodrugs for cancer therapy."2.46Perspectives for novel mixed diruthenium-organic drugs as metallopharmaceuticals in cancer therapy. ( Silva, Dde O, 2010)
"A total of nine pseudoaneurysms treated by Onyx embolization were identified."1.39Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature. ( Jadhav, AP; Nogueira, RG; Pryor, JC, 2013)
"Glioblastoma multiforme is composed of multiple cellular compartments with different morphologic, kinetic, metabolic, vascular, and genetic properties."1.26Aggressive multimodality therapy based on a multicompartmental model of glioblastoma. ( Broadwell, RD; Ducker, TB; Kaplan, RS; Salcman, M; Samaras, GM, 1982)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Day, EK1
Zhong, Q1
Purow, B1
Lazzara, MJ1
Ricci, M1
Ragonese, F1
Gironi, B1
Paolantoni, M1
Morresi, A1
Latterini, L1
Fioretti, B1
Sassi, P1
Silva, Dde O1
Delgado-Goñi, T1
Martín-Sitjar, J1
Simões, RV1
Acosta, M1
Lope-Piedrafita, S1
Arús, C1
Jadhav, AP1
Pryor, JC1
Nogueira, RG1
Quayle, SN1
Lee, JY1
Cheung, LW1
Ding, L1
Wiedemeyer, R1
Dewan, RW1
Huang-Hobbs, E1
Zhuang, L1
Wilson, RK1
Ligon, KL1
Mills, GB1
Cantley, LC1
Chin, L1
Shao, C1
Folkard, M1
Michael, BD1
Prise, KM1
Salcman, M2
Kaplan, RS2
Ducker, TB2
Abdo, H1
Montgomery, E1
Samaras, GM1
Broadwell, RD1
Huang, EY1
Madireddi, MT1
Gopalkrishnan, RV1
Leszczyniecka, M1
Su, Z1
Lebedeva, IV1
Kang, D1
Jiang, H1
Lin, JJ1
Alexandre, D1
Chen, Y1
Vozhilla, N1
Mei, MX1
Christiansen, KA1
Sivo, F1
Goldstein, NI1
Mhashilkar, AB1
Chada, S1
Huberman, E1
Pestka, S1
Fisher, PB1

Reviews

1 review available for dimethyl sulfoxide and Glioblastoma

ArticleYear
Perspectives for novel mixed diruthenium-organic drugs as metallopharmaceuticals in cancer therapy.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Dimethyl Sulfoxide; Gliobla

2010

Other Studies

9 other studies available for dimethyl sulfoxide and Glioblastoma

ArticleYear
Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Data Science; Dimethyl Sulfoxide; DNA Repair; Drug Resis

2021
Glioblastoma single-cell microRaman analysis under stress treatments.
    Scientific reports, 2018, 05-22, Volume: 8, Issue:1

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dimethyl Sulfoxide; Glioblastoma; Glucose; Humans; Hyd

2018
Dimethyl sulfoxide (DMSO) as a potential contrast agent for brain tumors.
    NMR in biomedicine, 2013, Volume: 26, Issue:2

    Topics: Animals; Brain Neoplasms; Contrast Media; Dimethyl Sulfoxide; Feasibility Studies; Female; Glioblast

2013
Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature.
    Journal of neurointerventional surgery, 2013, Volume: 5, Issue:6

    Topics: Adult; Aged; Aneurysm, False; Aneurysm, Infected; Anterior Cerebral Artery; Brain Injuries; Brain Ne

2013
Somatic mutations of PIK3R1 promote gliomagenesis.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Analysis of Variance; Astrocytes; Cell Survival; Cell Transformation, Neoplastic; Class Ia Phosphati

2012
Bystander signaling between glioma cells and fibroblasts targeted with counted particles.
    International journal of cancer, 2005, Aug-10, Volume: 116, Issue:1

    Topics: Antioxidants; Benzoates; Bystander Effect; Cell Communication; Cell Line; Cell Line, Tumor; Cocultur

2005
Effect of age and reoperation on survival in the combined modality treatment of malignant astrocytoma.
    Neurosurgery, 1982, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Neoplasms; Carmustine; Dimethyl Sulfoxide; Doxorubicin;

1982
Aggressive multimodality therapy based on a multicompartmental model of glioblastoma.
    Surgery, 1982, Volume: 92, Issue:2

    Topics: Brain Neoplasms; Carmustine; Dimethyl Sulfoxide; Drug Therapy, Combination; Glioblastoma; Hot Temper

1982
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
    Oncogene, 2001, Oct-25, Volume: 20, Issue:48

    Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromo

2001