embelin has been researched along with Glioblastoma in 2 studies
embelin: from Embelia fruit (Myrsinaceae)
embelin : A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Taking into account that lipoxygenase (LOX) metabolites, from arachidonic acid and linoleic acid, have been implicated in tumor progression, here, we determined whether RF-Id was able to hinder glioblastoma (GBM) cancer cell growth and the related mechanisms." | 3.83 | The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells. ( Caraglia, M; Cossu, AM; De Rosa, M; Filosa, R; Ingrosso, D; Schiraldi, C; Scuotto, M; Zappavigna, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanrikulu, B | 1 |
| Ziyal, I | 1 |
| Bayri, Y | 1 |
| Zappavigna, S | 1 |
| Scuotto, M | 1 |
| Cossu, AM | 1 |
| Ingrosso, D | 1 |
| De Rosa, M | 1 |
| Schiraldi, C | 1 |
| Filosa, R | 1 |
| Caraglia, M | 1 |
2 other studies available for embelin and Glioblastoma
| Article | Year |
|---|---|
In Vitro Effects of Mesenchymal Stem Cells and Various Agents on Apoptosis of Glioblastoma Cells.
Topics: Adult; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Line, Tumor; Gene Silencing; Glioblasto | 2019 |
The 1,4 benzoquinone-featured 5-lipoxygenase inhibitor RF-Id induces apoptotic death through downregulation of IAPs in human glioblastoma cells.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Autophagy; Benzoquinones; Brain Neoplasms; Cell Line, | 2016 |