monodansylcadaverine has been researched along with Glioblastoma in 2 studies
monodansylcadaverine: inhibits cross linkage of fibrin
monodansylcadaverine : A sulfonamide obtained by formal condensation of the sulfo group of 5-(dimethylamino)naphthalene-1-sulfonic acid with one of the amino groups of cadaverine.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
Excerpt | Relevance | Reference |
---|---|---|
"Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need." | 5.46 | Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line. ( Cheng, B; Mito, S; Morales, LD; Tsin, A; Zhang, Y, 2017) |
"Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need." | 1.46 | Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line. ( Cheng, B; Mito, S; Morales, LD; Tsin, A; Zhang, Y, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cheng, B | 1 |
Morales, LD | 1 |
Zhang, Y | 1 |
Mito, S | 1 |
Tsin, A | 1 |
Yuan, L | 1 |
Choi, K | 1 |
Khosla, C | 1 |
Zheng, X | 1 |
Higashikubo, R | 1 |
Chicoine, MR | 1 |
Rich, KM | 1 |
2 other studies available for monodansylcadaverine and Glioblastoma
Article | Year |
---|---|
Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line.
Topics: Anthelmintics; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cadaverine; Cell Line, Tumor; Cell | 2017 |
Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas.
Topics: Animals; Apoptosis Regulatory Proteins; Azo Compounds; Bcl-2-Like Protein 11; Brain Neoplasms; Cadav | 2005 |