caffeine has been researched along with Glioblastoma in 8 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide (TMZ) is the first-line chemotherapeutic agent in the treatment of glioblastoma multiforme (GBM)." | 7.88 | Caffeine Sensitizes U87-MG Human Glioblastoma Cells to Temozolomide through Mitotic Catastrophe by Impeding G2 Arrest. ( Cheng, YS; Kiang, KMY; Leung, GKK; Li, N; Zhang, P, 2018) |
| "To study the effects and associated mechanisms of caffeine on cell viability, cycle dynamics, proliferation and apoptosis both in glioblastoma C6 and U87MG cells." | 7.81 | Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro. ( Feng, YY; Liu, JD; Song, LJ; Yan, DJ; Yang, Y; Zang, YG, 2015) |
| "We studied the effects of caffeine on cell viability, cell cycle profiles, proliferation, and apoptosis in rat C6 and human U87MG glioblastoma cell lines." | 7.81 | The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas. ( Chen, XP; Jiang, J; Lan, YQ; Li, LH; Liu, XY; Yu, M; Zhang, T, 2015) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 5.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "Temozolomide (TMZ) is the first-line chemotherapeutic agent in the treatment of glioblastoma multiforme (GBM)." | 3.88 | Caffeine Sensitizes U87-MG Human Glioblastoma Cells to Temozolomide through Mitotic Catastrophe by Impeding G2 Arrest. ( Cheng, YS; Kiang, KMY; Leung, GKK; Li, N; Zhang, P, 2018) |
| "To study the effects and associated mechanisms of caffeine on cell viability, cycle dynamics, proliferation and apoptosis both in glioblastoma C6 and U87MG cells." | 3.81 | Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro. ( Feng, YY; Liu, JD; Song, LJ; Yan, DJ; Yang, Y; Zang, YG, 2015) |
| "We studied the effects of caffeine on cell viability, cell cycle profiles, proliferation, and apoptosis in rat C6 and human U87MG glioblastoma cell lines." | 3.81 | The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas. ( Chen, XP; Jiang, J; Lan, YQ; Li, LH; Liu, XY; Yu, M; Zhang, T, 2015) |
| "Despite aggressive therapy comprising radical radiation and temozolomide (TMZ) chemotherapy, the prognosis for patients with glioblastoma multiforme (GBM) remains poor, particularly if tumors express O(6)-methylguanine-DNA-methyltransferase (MGMT)." | 3.75 | Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent. ( Chalmers, AJ; Lovegrove, N; Martindale, C; Ruff, EM; Short, SC, 2009) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 1.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maugeri, G | 1 |
| D'Amico, AG | 1 |
| Rasà , DM | 1 |
| Saccone, S | 1 |
| Federico, C | 1 |
| Magro, G | 1 |
| Cavallaro, S | 1 |
| D'Agata, V | 1 |
| Li, N | 1 |
| Zhang, P | 1 |
| Kiang, KMY | 1 |
| Cheng, YS | 1 |
| Leung, GKK | 1 |
| Liu, JD | 1 |
| Song, LJ | 1 |
| Yan, DJ | 1 |
| Feng, YY | 1 |
| Zang, YG | 1 |
| Yang, Y | 1 |
| Jiang, J | 1 |
| Lan, YQ | 1 |
| Zhang, T | 1 |
| Yu, M | 1 |
| Liu, XY | 1 |
| Li, LH | 1 |
| Chen, XP | 1 |
| Sun, F | 1 |
| Han, DF | 1 |
| Cao, BQ | 1 |
| Wang, B | 1 |
| Dong, N | 1 |
| Jiang, DH | 1 |
| Cheng, YC | 1 |
| Ding, YM | 1 |
| Hueng, DY | 1 |
| Chen, JY | 1 |
| Chen, Y | 1 |
| Chalmers, AJ | 1 |
| Ruff, EM | 1 |
| Martindale, C | 1 |
| Lovegrove, N | 1 |
| Short, SC | 1 |
| Kang, SS | 1 |
| Han, KS | 1 |
| Ku, BM | 1 |
| Lee, YK | 1 |
| Hong, J | 1 |
| Shin, HY | 1 |
| Almonte, AG | 1 |
| Woo, DH | 1 |
| Brat, DJ | 1 |
| Hwang, EM | 1 |
| Yoo, SH | 1 |
| Chung, CK | 1 |
| Park, SH | 1 |
| Paek, SH | 1 |
| Roh, EJ | 1 |
| Lee, SJ | 1 |
| Park, JY | 1 |
| Traynelis, SF | 1 |
| Lee, CJ | 1 |
8 other studies available for caffeine and Glioblastoma
| Article | Year |
|---|---|
Caffeine Effect on HIFs/VEGF Pathway in Human Glioblastoma Cells Exposed to Hypoxia.
Topics: Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Caffeine; Cell Line, Tumor; Cel | 2018 |
Caffeine Sensitizes U87-MG Human Glioblastoma Cells to Temozolomide through Mitotic Catastrophe by Impeding G2 Arrest.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Caffeine; Cell Line, Tumor; Central Nervous System Sti | 2018 |
Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Surviva | 2015 |
The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cel | 2015 |
Caffeine-induced nuclear translocation of FoxO1 triggers Bim-mediated apoptosis in human glioblastoma cells.
Topics: Active Transport, Cell Nucleus; Apoptosis; Bcl-2-Like Protein 11; Caffeine; Cell Nucleus; Forkhead B | 2016 |
Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Brain Neoplasms; Caffeine; Cathepsin | 2016 |
Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent.
Topics: Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Prot | 2009 |
Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival.
Topics: Animals; Caffeine; Calcium; Cell Line; Cell Line, Tumor; Cell Movement; Cell Survival; Central Nervo | 2010 |