ciglitazone has been researched along with Glioblastoma in 5 studies
ciglitazone: structure given in second source; PPAR agonist used for type II diabetes
ciglitazone : An aromatic ether that consists of 1,3-thiazolidine-2,4-dione with position 5 substituted by a 4-[(1-methylcyclohexyl)methoxy]benzyl group. A selective PPARgamma agonist.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma multiforme is the most common malignant brain tumor in adults, and it is among the most lethal of all cancers." | 5.32 | The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines. ( Bouchal, J; Dzubak, P; Ehrmann, J; Kolar, Z; Strakova, N, 2004) |
| "Glioblastoma multiforme is the most common malignant brain tumor in adults, and it is among the most lethal of all cancers." | 1.32 | The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines. ( Bouchal, J; Dzubak, P; Ehrmann, J; Kolar, Z; Strakova, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheu, ML | 1 |
| Pan, LY | 1 |
| Hu, HY | 1 |
| Su, HL | 1 |
| Sheehan, J | 1 |
| Tsou, HK | 1 |
| Pan, HC | 1 |
| Ehrmann, J | 3 |
| Strakova, N | 3 |
| Vrzalikova, K | 1 |
| Hezova, R | 1 |
| Kolar, Z | 3 |
| Dzubak, P | 1 |
| Bouchal, J | 1 |
| Bartos, J | 1 |
| Malikova, J | 1 |
| Dolezel, J | 1 |
| Galetto, R | 1 |
| Albajar, M | 1 |
| Polanco, JI | 1 |
| Zakin, MM | 1 |
| RodrÃguez-Rey, JC | 1 |
5 other studies available for ciglitazone and Glioblastoma
| Article | Year |
|---|---|
Potential Therapeutic Effects of Thiazolidinedione on Malignant Glioma.
Topics: Animals; Cell Cycle Proteins; Cell Line, Tumor; Diabetes Mellitus, Type 2; Glioblastoma; Glioma; Hyp | 2022 |
Expression of STATs and their inhibitors SOCS and PIAS in brain tumors. In vitro and in vivo study.
Topics: Brain Neoplasms; Cell Line, Tumor; Gene Expression; Glioblastoma; Humans; Molecular Chaperones; Phos | 2008 |
The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines.
Topics: Adult; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell | 2004 |
Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors.
Topics: Apoptosis; Bezafibrate; Brain Neoplasms; Cell Cycle; Cell Differentiation; Cell Survival; Flow Cytom | 2005 |
Identification of a peroxisome-proliferator-activated-receptor response element in the apolipoprotein E gene control region.
Topics: Animals; Apolipoproteins E; Astrocytoma; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Protei | 2001 |