meropenem and Glioblastoma

Caulobacter spp. are Gram-negative bacteria that have rarely been found to be pathogenic in humans.. This report describes the first case, to our knowledge, of meningitis in an adult patient caused by Caulobacter spp. A 75-year-old man was operated for a glioblastoma with no evident signs of primary infection in the wound site. Eight days after surgery, the patient developed signs and symptoms of meningitis. Caulobacter was then isolated on 3 separate occasions in the patient's cerebrospinal fluid. Thereafter, specific antibiotic therapy began. After 2 weeks of therapy, the patient was discharged with complete resolution of any related symptoms.. Caulobacter spp. can cause adult meningitis even where there is no evidence of surgical site infection.

Topics: Aged; Brain Neoplasms; Caulobacter; Cerebrospinal Fluid; Glioblastoma; Gram-Negative Bacterial Infections; Humans; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Postoperative Complications; Thienamycins; Virulence