Page last updated: 2024-08-17

nad and Glioblastoma

nad has been researched along with Glioblastoma in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (45.83)24.3611
2020's9 (37.50)2.80

Authors

AuthorsStudies
Gunn, B; Keniry, M; Litif, C; Lopez, A; Schuenzel, E; Udawant, S1
Barger, C; Batsios, G; Costello, JF; Gillespie, AM; Ronen, SM; Stevers, N; Taglang, C; Tran, M; Viswanath, P1
Gao, JJ; He, D; Ji, XS; Liu, Q; Liu, ZH; Pang, B; Pang, Q; Qin, Z; Sun, J; Wang, ZX; Wei, YB; Xin, T; Yang, F1
Karpel-Massler, G; Nguyen, TTT; Shang, E; Siegelin, MD; Westhoff, MA1
Chun, JH; Huang, RCC; Jackson, TLB; Kimura, K; Liang, YC; Lin, YL1
Baklaushev, VP; Dudenkova, VV; Gavrina, AI; Lukina, MM; Mozherov, AM; Sachkova, DA; Shirmanova, MV; Yashin, KS; Yusubalieva, GM; Yuzhakova, DV1
Lin, Z; Quan, C; Quan, J; Xu, R; Yang, S; Yang, Y; Zheng, L1
Clark, P; Datta, R; Eliceiri, K; Kuo, J; Pointer, K; Schroeder, A1
Cahill, DP; Kirtane, AR; Kiyokawa, J; Lee, CK; Li, M; Lopes, A; Nagashima, H; Tirmizi, ZA; Traverso, G; Wakimoto, H1
Cho, YS; Chung, KS; Kim, JY; Kwon, Y; Mun, SJ; Ryu, JS; Son, MJ1
Chaumeil, MM; Gaensler, K; Ito, M; Jalbert, LE; Mukherjee, J; Nelson, SJ; Park, I; Pieper, RO; Ronen, SM1
Cooney, A; Goldstein, DS; Jinsmaa, Y; Kopin, IJ; Sharabi, Y; Sullivan, P1
Lu, YB; Shi, QJ; Wei, EQ; Wu, M; Yang, P; Zhang, L; Zhang, WP1
Batchelor, TT; Bedel, O; Cahill, DP; Chi, AS; Curry, WT; Deng, G; Fisher, DE; Flaherty, KT; Gerszten, RE; He, T; Ho, Q; Iafrate, AJ; Kemeny, LV; Koerner, MVA; Lelic, N; Loebel, F; Nigim, F; Roider, EM; Samuels, Y; Shi, X; Sundaram, S; Tanaka, S; Tateishi, K; Wakimoto, H; Wiederschain, D; Yeh, JJ; Zhang, B; Zhang, Y; Zhao, D1
Shipman, L1
Batchelor, TT; Cahill, DP; Chi, AS; Curry, WT; Flaherty, KT; Ho, Q; Iafrate, AJ; Lelic, N; Onozato, ML; Sundaram, S; Tateishi, K; Wakimoto, H1
Aum, D; Dadey, DY; Dahiya, S; Gujar, AD; Hallahan, DE; Kim, AH; Le, S; Luo, J; Mao, DD; Milbrandt, J; Rich, KM; Sasaki, Y; Tran, DD; Turski, A; Yano, H; Yuan, L1
Bareket, L; Berkovitch, G; Nudelman, A; Rephaeli, A; Rishpon, J1
Brown, AR; Goellner, EM; Grimme, B; Lin, YC; Mitchell, L; Sobol, RW; Sugrue, KF; Tang, JB; Trivedi, RN; Wang, XH1
Fang, SH; Hu, H; Ling, KN; Liu, LY; Lu, YB; Qie, LL; Wang, F; Wei, EQ; Xu, LH; Zhang, LY; Zhang, WP1
FABIANI, A; SCHIFFER, D; VESCO, C1
MUELLER, W; NASU, H1
Kirsch, WM; Leitner, JW; Schulz, D1
Kirsch, WM; Schulz, DW1

Other Studies

24 other study(ies) available for nad and Glioblastoma

ArticleYear
PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells.
    Cells, 2021, 11-07, Volume: 10, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Gene Ontology; Glioblastoma; Glucose; Glutamic Acid; Glycolysis; Humans; Imidazoles; Kaplan-Meier Estimate; Lactic Acid; NAD; Phosphatidylinositol 3-Kinases; Prognosis; Protein Kinase Inhibitors; Quinolines; Signal Transduction

2021
Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 08-15, Volume: 28, Issue:16

    Topics: Animals; Deuterium; Glioblastoma; Lactic Acid; Mice; NAD; Pyruvic Acid; Telomerase

2022
A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-17, Volume: 41, Issue:1

    Topics: Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Malate Dehydrogenase; NAD; RNA, Long Noncoding

2022
Targeting cellular respiration as a therapeutic strategy in glioblastoma.
    Oncotarget, 2023, 05-04, Volume: 14

    Topics: Cell Respiration; Citric Acid Cycle; Energy Metabolism; Glioblastoma; Glucose; Glycolysis; Humans; NAD; Oxidoreductases

2023
Tetra-O-methyl-nordihydroguaiaretic acid inhibits energy metabolism and synergistically induces anticancer effects with temozolomide on LN229 glioblastoma tumors implanted in mice while preventing obesity in normal mice that consume high-fat diets.
    PloS one, 2023, Volume: 18, Issue:5

    Topics: Animals; Cell Line, Tumor; Diet, High-Fat; Energy Metabolism; Glioblastoma; Humans; Masoprocol; Mice; NAD; Temozolomide; Tumor Microenvironment

2023
Development of a 3D Tumor Spheroid Model from the Patient's Glioblastoma Cells and Its Study by Metabolic Fluorescence Lifetime Imaging.
    Sovremennye tekhnologii v meditsine, 2023, Volume: 15, Issue:2

    Topics: Coenzymes; Cytoplasm; Glioblastoma; Glioma; Humans; Hypoxia; NAD

2023
NQO1 drives glioblastoma cell aggressiveness through EMT induction via the PI3K/Akt/mTOR/Snail pathway.
    International journal of oncology, 2023, Volume: 63, Issue:4

    Topics: Aggression; Glioblastoma; Humans; NAD; NAD(P)H Dehydrogenase (Quinone); Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2023
Metabolic mapping of glioblastoma stem cells reveals NADH fluxes associated with glioblastoma phenotype and survival.
    Journal of biomedical optics, 2020, Volume: 25, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioblastoma; Heterografts; Humans; Metabolic Flux Analysis; Metabolic Networks and Pathways; Mice; Mice, Inbred NOD; Mice, SCID; Microscopy, Fluorescence, Multiphoton; NAD; Phenotype; Stem Cells; Xenograft Model Antitumor Assays

2020
Local Targeting of NAD
    Cancer research, 2020, 11-15, Volume: 80, Issue:22

    Topics: Acrylamides; Animals; Autophagy; B7-H1 Antigen; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Movement; Cyanides; Cytokines; Delayed-Action Preparations; Drug Carriers; Glioblastoma; Guanidines; Humans; Injections, Intralesional; Macrophages; Membrane Proteins; Mice; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Polymers; RNA, Messenger; Signal Transduction; Tumor Microenvironment; Up-Regulation

2020
Upregulation of mitochondrial NAD
    Experimental & molecular medicine, 2017, 06-09, Volume: 49, Issue:6

    Topics: Aging; Animals; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Colony-Forming Units Assay; Glioblastoma; Humans; Lactic Acid; Lewis X Antigen; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP Transhydrogenases; Neoplastic Stem Cells; Oxygen Consumption; RNA, Small Interfering; Sirtuin 3; Xenograft Model Antitumor Assays

2017
Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells.
    Cancer research, 2014, Dec-01, Volume: 74, Issue:23

    Topics: Apoptosis; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Dacarbazine; DNA Damage; DNA Repair; Gene Expression; Glioblastoma; Humans; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Membrane Proteins; Methyltransferases; NAD; Protein Kinases; Pyruvic Acid; Temozolomide; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014
Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease.
    Journal of neurochemistry, 2015, Volume: 133, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehyde Dehydrogenase; Animals; Brain Neoplasms; Dopamine; Electron Transport Complex I; Glioblastoma; Glioma; Humans; NAD; Parkinson Disease, Secondary; PC12 Cells; Rats; Rotenone; Uncoupling Agents

2015
Nicotinamide phosphoribosyltransferase inhibitor APO866 induces C6 glioblastoma cell death via autophagy.
    Die Pharmazie, 2015, Volume: 70, Issue:10

    Topics: Acrylamides; Animals; Autophagy; Cell Death; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Glioblastoma; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Rats; Vacuoles

2015
Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.
    Cancer cell, 2015, Dec-14, Volume: 28, Issue:6

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Autophagy; Brain Neoplasms; Cell Proliferation; Cytokines; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Female; Glioblastoma; Glutarates; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Metabolomics; Mice, SCID; Molecular Targeted Therapy; Mutation; NAD; Nicotinamide Phosphoribosyltransferase; Pentosyltransferases; Signal Transduction; Spheroids, Cellular; Time Factors; Transfection; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Metabolism: Totally addicted to NAD(.).
    Nature reviews. Cancer, 2016, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cytokines; Enzyme Inhibitors; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Mutation; NAD; Nicotinamide Phosphoribosyltransferase

2016
Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Sep-01, Volume: 22, Issue:17

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Gene Amplification; Glioblastoma; Glucose; Glycolysis; Humans; Mice; NAD; Nicotinamide Phosphoribosyltransferase; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Xenograft Model Antitumor Assays

2016
An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 12-20, Volume: 113, Issue:51

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cytokines; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Mutation; NAD; Neoplasm Transplantation; Nicotinamide Phosphoribosyltransferase; Radiation Tolerance; RNA Interference; Signal Transduction; Stem Cells; Transcription, Genetic

2016
Carbon nanotubes based electrochemical biosensor for detection of formaldehyde released from a cancer cell line treated with formaldehyde-releasing anticancer prodrugs.
    Bioelectrochemistry (Amsterdam, Netherlands), 2010, Volume: 77, Issue:2

    Topics: Acetaldehyde; Antineoplastic Agents; Biosensing Techniques; Butyric Acid; Cell Line, Tumor; Electrochemistry; Electrodes; Formaldehyde; Glioblastoma; Humans; NAD; Nanotubes, Carbon; Prodrugs; Time Factors

2010
Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair.
    Cancer research, 2011, Mar-15, Volume: 71, Issue:6

    Topics: Acrylamides; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Glioblastoma; Humans; Hydroxylamines; Immunoblotting; Methyl Methanesulfonate; NAD; Piperidines; Poly(ADP-ribose) Polymerases; RNA Interference; Temozolomide

2011
Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase.
    European journal of pharmacology, 2012, Jan-15, Volume: 674, Issue:2-3

    Topics: Acrylamides; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Intracellular Space; M Phase Cell Cycle Checkpoints; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Rats

2012
HISTOCHEMICAL STUDY OF ROSENTHAL FIBRES, WITH OBSERVATIONS ABOUT SOME ENZYME ACTIVITIES.
    Psychiatria et neurologia, 1964, Volume: 147

    Topics: Acid Phosphatase; Adenosine Triphosphate; Alkaline Phosphatase; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; Dihydrolipoamide Dehydrogenase; Electron Transport Complex II; Ependyma; Esterases; Glioblastoma; Glucose-6-Phosphatase; Hemangiosarcoma; Histocytochemistry; Intracranial Arteriosclerosis; L-Lactate Dehydrogenase; NAD; NADP; Oligodendroglioma; Succinate Dehydrogenase

1964
[ENZYME HISTOCHEMICAL STUDIES ON GLIOMA].
    Deutsche Zeitschrift fur Nervenheilkunde, 1964, Apr-23, Volume: 186

    Topics: Acid Phosphatase; Alkaline Phosphatase; Astrocytoma; Brain; Brain Neoplasms; Esterases; Glioblastoma; Glioma; NAD; NADP; Neurochemistry; Oligodendroglioma; Oxidoreductases

1964
The quantitative histochemistry of the experimental glioblastoma: glycolysis and growth.
    Acta histochemica, 1967, Volume: 28, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Creatine Kinase; Glioblastoma; Glucose; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glutamate Dehydrogenase; Glycogen; Glycolysis; Hexokinase; Histocytochemistry; Ischemia; Lactates; Mice; NAD; NADP; Neoplasms, Experimental; Phosphates; Phosphocreatine; Phosphoglucomutase; Phosphogluconate Dehydrogenase

1967
Regional bioenergetic events in the experimental glioblastoma. Aquantitative histochemical study.
    Journal of neurosurgery, 1971, Volume: 34, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Disease Models, Animal; Fluorometry; Freezing; Glioblastoma; Glucose; Glycogen; Histocytochemistry; Lactates; Mice; NAD; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Neuroglia; Oxygen Consumption; Pentoses; Phosphates; Phosphocreatine; Transplantation, Homologous

1971