8-prenylnaringenin has been researched along with Glioblastoma* in 1 studies
1 other study(ies) available for 8-prenylnaringenin and Glioblastoma
| Article | Year |
|---|---|
In Vitro Effect of 8-Prenylnaringenin and Naringenin on Fibroblasts and Glioblastoma Cells-Cellular Accumulation and Cytotoxicity.
Gliomas are one of the most aggressive and treatment-resistant types of human brain cancer. Identification and evaluation of anticancer properties of compounds found in plants, such as naringenin (N) and 8-prenylnaringenin (8PN), are among the most promising applications in glioma therapy. The prenyl group seems to be crucial to the anticancer activity of flavones, since it may lead to enhanced cell membrane targeting and thus increased intracellular activity. It should be noted that 8PN content in hop cones is 10 to 100 times lower compared to other flavonoids, such as xanthohumol. In the study presented, we used a simple method for the synthesis of 8PN from isoxanthohumol- Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Fibroblasts; Flavanones; Glioblastoma; Humans; Molecular Structure | 2017 |