uracil has been researched along with Glioblastoma in 4 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nineteen patients with brain tumors were orally administered 300 mg of UFT (a combination of FT and uracil with a molar ratio being 1:4) before operation and the concentrations of FT, 5-FU and Uracil in tumors and serum were measured by chemical assay." | 1.27 | [5-FU concentration in brain tumors after co-administration of FT and uracil]. ( Matsumoto, S; Nogaki, H; Tamaki, N; Taomoto, K, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Warfield, BM | 1 |
| Matheson, CJ | 1 |
| McArthur, DG | 1 |
| Backos, DS | 1 |
| Reigan, P | 1 |
| Tsukamoto, Y | 1 |
| Ohtsu, N | 1 |
| Echizenya, S | 1 |
| Otsuguro, S | 1 |
| Ogura, R | 1 |
| Natsumeda, M | 1 |
| Isogawa, M | 1 |
| Aoki, H | 1 |
| Ichikawa, S | 1 |
| Sakaitani, M | 1 |
| Matsuda, A | 1 |
| Maenaka, K | 1 |
| Fujii, Y | 1 |
| Kondo, T | 1 |
| Nogaki, H | 1 |
| Taomoto, K | 1 |
| Tamaki, N | 1 |
| Matsumoto, S | 1 |
| Sanderson, RJ | 1 |
| Mosbaugh, DW | 1 |
4 other studies available for uracil and Glioblastoma
| Article | Year |
|---|---|
Evaluation of Thymidine Phosphorylase Inhibitors in Glioblastoma and Their Capacity for Temozolomide Potentiation.
Topics: Cell Line; Glioblastoma; Humans; Temozolomide; Thymidine Phosphorylase; Uracil | 2021 |
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.
Topics: 5'-Nucleotidase; Animals; Brain Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell | 2016 |
[5-FU concentration in brain tumors after co-administration of FT and uracil].
Topics: Brain Neoplasms; Drug Therapy, Combination; Fluorouracil; Glioblastoma; Humans; Meningeal Neoplasms; | 1983 |
Fidelity and mutational specificity of uracil-initiated base excision DNA repair synthesis in human glioblastoma cell extracts.
Topics: Bacillus Phages; Base Sequence; beta-Galactosidase; Cell-Free System; Codon; DNA Glycosylases; DNA R | 1998 |