ci 994 and Glioblastoma
ci 994 has been researched along with Glioblastoma in 1 studies
tacedinaline: oral cytostatic drug with impressive differential activity against leukemic cells & normal stem-cells
tacedinaline : A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Marquardt, V | 1 |
| Theruvath, J | 1 |
| Pauck, D | 1 |
| Picard, D | 1 |
| Qin, N | 1 |
| Blümel, L | 1 |
| Maue, M | 1 |
| Bartl, J | 1 |
| Ahmadov, U | 1 |
| Langini, M | 1 |
| Meyer, FD | 1 |
| Cole, A | 1 |
| Cruz-Cruz, J | 1 |
| Graef, CM | 1 |
| Wölfl, M | 1 |
| Milde, T | 1 |
| Witt, O | 1 |
| Erdreich-Epstein, A | 1 |
| Leprivier, G | 1 |
| Kahlert, U | 1 |
| Stefanski, A | 1 |
| Stühler, K | 1 |
| Keir, ST | 1 |
| Bigner, DD | 1 |
| Hauer, J | 1 |
| Beez, T | 1 |
| Knobbe-Thomsen, CB | 1 |
| Fischer, U | 1 |
| Felsberg, J | 1 |
| Hansen, FK | 1 |
| Vibhakar, R | 1 |
| Venkatraman, S | 1 |
| Cheshier, SH | 1 |
| Reifenberger, G | 1 |
| Borkhardt, A | 1 |
| Kurz, T | 1 |
| Remke, M | 1 |
| Mitra, S | 1 |
Other Studies
1 other study available for ci 994 and Glioblastoma
| Article | Year |
|---|---|
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammat
Topics: Animals; Cerebellar Neoplasms; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Inflammation; M | 2023 |