calyculin-a has been researched along with Glioblastoma* in 1 studies
1 other study(ies) available for calyculin-a and Glioblastoma
| Article | Year |
|---|---|
Cordycepin inhibits migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation.
Cordycepin, a nucleoside-derivative-isolated form Cordyceps militaris, has been reported to suppress tumor cell proliferation and cause apoptosis. This study investigates the effect of cordycepin on the migration of human glioblastoma cells. Cordycepin suppressed the migration of the human glioblastoma cell lines U87MG and LN229 in transwell and wound healing assays. Cordycepin decreased protein expression of integrin α1, focal adhesion kinase (FAK), p-FAK, paxillin and p-paxillin. The lysosomal inhibitor NH Topics: Ammonium Chloride; Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Deoxyadenosines; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lysosomes; Marine Toxins; Mice, Nude; Neoplasm Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Proteolysis; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |