arsenicin-a has been researched along with Glioblastoma* in 1 studies
1 other study(ies) available for arsenicin-a and Glioblastoma
| Article | Year |
|---|---|
Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth.
The marine polyarsenical metabolite arsenicin A is the landmark of a series of natural and synthetic molecules characterized by an adamantane-like tetraarsenic cage. Arsenicin A and related polyarsenicals have been evaluated for their antitumor effects in vitro and have been proven more potent than the FDA-approved arsenic trioxide. In this context, we have expanded the chemical space of polyarsenicals related to arsenicin A by synthesizing dialkyl and dimethyl thio-analogs, the latter characterized with the support of simulated NMR spectra. In addition, the new natural arsenicin D, the scarcity of which in the Topics: Adamantane; Arsenic Trioxide; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Stem Cells | 2023 |