ici 204,219 has been researched along with Glioblastoma in 1 studies
zafirlukast: a leukotriene D4 receptor antagonist
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Montelukast was more cytotoxic and induced higher levels of apoptosis than zafirlukast in A172 cells, but not in U-87 MG cells." | 1.48 | Cysteinyl leukotriene receptor antagonists induce apoptosis and inhibit proliferation of human glioblastoma cells by downregulating B-cell lymphoma 2 and inducing cell cycle arrest. ( Chaithirayanon, K; Chongthammakun, S; Parakaw, T; Phuagkhaopong, S; Piromkraipak, P; Srihirun, S; Vivithanaporn, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piromkraipak, P | 1 |
| Parakaw, T | 1 |
| Phuagkhaopong, S | 1 |
| Srihirun, S | 1 |
| Chongthammakun, S | 1 |
| Chaithirayanon, K | 1 |
| Vivithanaporn, P | 1 |
1 other study available for ici 204,219 and Glioblastoma
| Article | Year |
|---|---|
Cysteinyl leukotriene receptor antagonists induce apoptosis and inhibit proliferation of human glioblastoma cells by downregulating B-cell lymphoma 2 and inducing cell cycle arrest.
Topics: Acetates; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferati | 2018 |