Page last updated: 2024-11-08

triiodothyronine and Glioblastoma

triiodothyronine has been researched along with Glioblastoma in 3 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"Regorafenib demonstrated encouraging results in recurrent glioblastoma patients."8.31Association between thyroid function and regorafenib efficacy in patients with relapsed wild-type IDH glioblastoma: a large multicenter study. ( Bruno, F; Caccese, M; Cavallin, F; Cerretti, G; Chioffi, F; Coppola, M; Della Puppa, A; Denaro, L; Desideri, I; Fiorentino, A; Livi, L; Lombardi, G; Maccari, M; Padovan, M; Pittaro, A; Rudà, R, 2023)
"Regorafenib demonstrated encouraging results in recurrent glioblastoma patients."4.31Association between thyroid function and regorafenib efficacy in patients with relapsed wild-type IDH glioblastoma: a large multicenter study. ( Bruno, F; Caccese, M; Cavallin, F; Cerretti, G; Chioffi, F; Coppola, M; Della Puppa, A; Denaro, L; Desideri, I; Fiorentino, A; Livi, L; Lombardi, G; Maccari, M; Padovan, M; Pittaro, A; Rudà, R, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Caccese, M1
Desideri, I1
Padovan, M1
Bruno, F1
Cerretti, G1
Fiorentino, A1
Denaro, L1
Chioffi, F1
Della Puppa, A1
Maccari, M1
Cavallin, F1
Coppola, M1
Pittaro, A1
Rudà, R1
Livi, L1
Lombardi, G1
Pinna, G1
Meinhold, H1
Hiedra, L1
Thoma, R1
Hoell, T1
Gräf, KJ1
Stoltenburg-Didinger, G1
Eravci, M1
Prengel, H1
Brödel, O1
Finke, R1
Baumgartner, A1
Morales, P1
Bosch, A1
Lopez, R1
Nery, C1
Borras, F1
Rosa, M1

Other Studies

3 other studies available for triiodothyronine and Glioblastoma

ArticleYear
Association between thyroid function and regorafenib efficacy in patients with relapsed wild-type IDH glioblastoma: a large multicenter study.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:2

    Topics: Glioblastoma; Humans; Neoplasm Recurrence, Local; Retrospective Studies; Thyroid Function Tests; Thy

2023
Elevated 3,5-diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:5

    Topics: Astrocytoma; Brain Injuries; Brain Neoplasms; Craniocerebral Trauma; Diiodothyronines; Glioblastoma;

1997
Radiotherapy and L-triiodothyronine in the treatment of high-grade astrocytoma.
    Journal of surgical oncology, 1988, Volume: 39, Issue:2

    Topics: Adult; Aged; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Radiation T

1988