dapsone has been researched along with Glioblastoma in 7 studies
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This short note presents previous research data supporting a pilot study of metronomic dapsone during the entire course of glioblastoma treatment." | 8.02 | Research Supporting a Pilot Study of Metronomic Dapsone during Glioblastoma Chemoirradiation. ( Kast, RE, 2021) |
| " There are several potential mechanisms by which histone deacetylase inhibition may alter dapsone metabolism including changes in hepatic acetylation or N-glucuronidation leading to an increase in the bioavailability of dapsone's hematotoxic metabolites." | 5.42 | Hemolytic anemia in two patients with glioblastoma multiforme: A possible interaction between vorinostat and dapsone. ( Harmon, M; Lesser, GJ; Lewis, JA; Owen, J; Peacock, JE; Petty, WJ; Pirmohamed, M; Valente, K, 2015) |
| "This short note presents previous research data supporting a pilot study of metronomic dapsone during the entire course of glioblastoma treatment." | 4.02 | Research Supporting a Pilot Study of Metronomic Dapsone during Glioblastoma Chemoirradiation. ( Kast, RE, 2021) |
| " There are several potential mechanisms by which histone deacetylase inhibition may alter dapsone metabolism including changes in hepatic acetylation or N-glucuronidation leading to an increase in the bioavailability of dapsone's hematotoxic metabolites." | 1.42 | Hemolytic anemia in two patients with glioblastoma multiforme: A possible interaction between vorinostat and dapsone. ( Harmon, M; Lesser, GJ; Lewis, JA; Owen, J; Peacock, JE; Petty, WJ; Pirmohamed, M; Valente, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Kast, RE | 4 |
| Hill, QA | 1 |
| Wion, D | 1 |
| Mellstedt, H | 1 |
| Focosi, D | 1 |
| Karpel-Massler, G | 3 |
| Heiland, T | 1 |
| Halatsch, ME | 3 |
| Lewis, JA | 1 |
| Petty, WJ | 1 |
| Harmon, M | 1 |
| Peacock, JE | 1 |
| Valente, K | 1 |
| Owen, J | 1 |
| Pirmohamed, M | 1 |
| Lesser, GJ | 1 |
| Rizk, N | 1 |
| Kamiya-Matsuoka, C | 1 |
| Tremont-Lukats, IW | 1 |
| Walker, JG | 1 |
| Kadia, T | 1 |
| Brown, L | 1 |
| Juneja, HS | 1 |
| de Groot, JF | 1 |
| Scheuerle, A | 1 |
| Wirtz, CR | 1 |
| Lefranc, F | 1 |
3 reviews available for dapsone and Glioblastoma
| Article | Year |
|---|---|
Glioblastoma-synthesized G-CSF and GM-CSF contribute to growth and immunosuppression: Potential therapeutic benefit from dapsone, fenofibrate, and ribavirin.
Topics: Bone Marrow Cells; Brain; Cell Proliferation; Dapsone; Fenofibrate; Glioblastoma; Granulocyte Colony | 2017 |
The rationale of targeting neutrophils with dapsone during glioblastoma treatment.
Topics: Animals; Brain Neoplasms; Dapsone; Drug Delivery Systems; Glioblastoma; Humans; Neutrophil Infiltrat | 2011 |
Why dapsone stops seizures and may stop neutrophils' delivery of VEGF to glioblastoma.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Drug Delivery Systems; Glioblastoma; Humans; | 2012 |
4 other studies available for dapsone and Glioblastoma
| Article | Year |
|---|---|
Research Supporting a Pilot Study of Metronomic Dapsone during Glioblastoma Chemoirradiation.
Topics: Cimetidine; Dapsone; Glioblastoma; Humans; Interleukin-8; Pemphigoid, Bullous; Pharmaceutical Prepar | 2021 |
Hemolytic anemia in two patients with glioblastoma multiforme: A possible interaction between vorinostat and dapsone.
Topics: Anemia, Hemolytic; Dapsone; Female; Glioblastoma; Humans; Hydroxamic Acids; Middle Aged; Vorinostat | 2015 |
Lower Extremity Edema, Anxiety, and Cyanosis During Chemoradiation Therapy for Glioblastoma.
Topics: Anti-Infective Agents; Anxiety; Brain Neoplasms; Chemoradiotherapy; Cyanosis; Dapsone; Edema; Female | 2016 |
Dapsone induced methemoglobinemia in a patient with glioblastoma.
Topics: Anti-Infective Agents; Brain Stem Neoplasms; Dapsone; Glioblastoma; Humans; Male; Methemoglobinemia; | 2009 |