diacetyl has been researched along with Glioblastoma in 1 studies
butane-2,3-dione : An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral dosing of U87MG-Luc tumor bearing mice with diacetyl-bis(4-methylthiosemicarbazonato)-copperII (Cu(II)-ATSM), significantly enhanced Cu-level in GBM tumor." | 1.72 | Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition. ( Chaston, TB; He, W; Ismail, M; Li, Y; Lovejoy, DB; Muhammad, P; Rehman, FU; Shi, B; Wang, J; Wang, Y; Yang, W; Zheng, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ismail, M | 1 |
| Yang, W | 1 |
| Li, Y | 1 |
| Wang, Y | 1 |
| He, W | 1 |
| Wang, J | 1 |
| Muhammad, P | 1 |
| Chaston, TB | 1 |
| Rehman, FU | 1 |
| Zheng, M | 1 |
| Lovejoy, DB | 1 |
| Shi, B | 1 |
1 other study available for diacetyl and Glioblastoma
| Article | Year |
|---|---|
Biomimetic Dp44mT-nanoparticles selectively induce apoptosis in Cu-loaded glioblastoma resulting in potent growth inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Biomimetics; Caspase 3; Cell | 2022 |