Page last updated: 2024-10-29

isoflurane and Glioblastoma

isoflurane has been researched along with Glioblastoma in 2 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"Clinically relevant concentrations and incubation times of isoflurane could promote the viability and mobility of U251-GSCs, suggesting this general anaesthetic may have detrimental effects in glioblastoma by facilitating its growth and migration."7.83Isoflurane enhances the malignant potential of glioblastoma stem cells by promoting their viability, mobility in vitro and migratory capacity in vivo. ( Dangelmajer, S; Kahlert, UD; Lei, T; Li, M; Shahveranov, A; Xi, Q; Xie, R; Ye, D; Zhou, Y; Zhu, M, 2016)
"Clinically relevant concentrations and incubation times of isoflurane could promote the viability and mobility of U251-GSCs, suggesting this general anaesthetic may have detrimental effects in glioblastoma by facilitating its growth and migration."3.83Isoflurane enhances the malignant potential of glioblastoma stem cells by promoting their viability, mobility in vitro and migratory capacity in vivo. ( Dangelmajer, S; Kahlert, UD; Lei, T; Li, M; Shahveranov, A; Xi, Q; Xie, R; Ye, D; Zhou, Y; Zhu, M, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhu, M1
Li, M1
Zhou, Y1
Dangelmajer, S1
Kahlert, UD1
Xie, R1
Xi, Q1
Shahveranov, A1
Ye, D1
Lei, T1
Cata, JP1
Hagan, KB1
Bhavsar, SD1
Arunkumar, R1
Grasu, R1
Dang, A1
Carlson, R1
Arnold, B1
Potylchansky, Y1
Lipski, I1
McHugh, T1
Jimenez, F1
Nguyen, AT1
Feng, L1
Rahlfs, TF1

Other Studies

2 other studies available for isoflurane and Glioblastoma

ArticleYear
Isoflurane enhances the malignant potential of glioblastoma stem cells by promoting their viability, mobility in vitro and migratory capacity in vivo.
    British journal of anaesthesia, 2016, Volume: 116, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2016
The use of isoflurane and desflurane as inhalational agents for glioblastoma surgery. A survival analysis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 35

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Chemoradiotherapy; Combined Modality T

2017