loperamide has been researched along with Hyperglycemia in 4 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac depression induced by loperamide is enhanced by hyperglycemia due to higher MOR expression, which is associated with higher expression of STAT3 in the heart." | 7.85 | Loperamide-induced Cardiac Depression Is Enhanced by Hyperglycemia: Evidence Relevant to Loperamide Abuse. ( Cheng, JT; Cheng, YZ; Ku, PM; Lo, SH; Niu, CS; Niu, HS, 2017) |
| "Cardiac depression induced by loperamide is enhanced by hyperglycemia due to higher MOR expression, which is associated with higher expression of STAT3 in the heart." | 3.85 | Loperamide-induced Cardiac Depression Is Enhanced by Hyperglycemia: Evidence Relevant to Loperamide Abuse. ( Cheng, JT; Cheng, YZ; Ku, PM; Lo, SH; Niu, CS; Niu, HS, 2017) |
| "Treatment with stattic at a dose sufficient to inhibit STAT3 reversed MOR expression in STZ rats." | 1.40 | Signals for increase of μ-opioid receptor expression in muscle by hyperglycemia. ( Chen, LJ; Cheng, JT; Lin, KC; Niu, HS; Yang, TT; Yeh, MC, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lo, SH | 1 |
| Niu, HS | 2 |
| Cheng, YZ | 1 |
| Niu, CS | 1 |
| Cheng, JT | 4 |
| Ku, PM | 1 |
| Yeh, MC | 1 |
| Chen, LJ | 1 |
| Yang, TT | 1 |
| Lin, KC | 1 |
| Liu, IM | 2 |
| Chi, TC | 2 |
| Chen, YC | 1 |
| Lu, FH | 1 |
| Tzeng, TF | 1 |
4 other studies available for loperamide and Hyperglycemia
| Article | Year |
|---|---|
Loperamide-induced Cardiac Depression Is Enhanced by Hyperglycemia: Evidence Relevant to Loperamide Abuse.
Topics: Animals; Blood Pressure; Cell Line; Cyclic S-Oxides; Diabetes Mellitus, Experimental; Heart Rate; Hy | 2017 |
Signals for increase of μ-opioid receptor expression in muscle by hyperglycemia.
Topics: Animals; Cells, Cultured; Cyclic S-Oxides; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; | 2014 |
Activation of opioid mu-receptor by loperamide to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Animals; Antidiarrheals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, | 1999 |
Increase of opioid mu-receptor gene expression in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Gene Expression; Hyperg | 2001 |