Proteins > Extracellular calcium-sensing receptor
Page last updated: 2024-08-07 16:44:03
Extracellular calcium-sensing receptor
An extracellular calcium-sensing receptor that is encoded in the genome of rat. [OMA:P48442, PRO:DNx]
Synonyms
CaSR;
Parathyroid cell calcium-sensing receptor;
PCaR1;
RaKCaR
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| nps2143 | Rattus norvegicus (Norway rat) | IC50 | 0.4950 | 2 | 2 |
| ronacaleret | Rattus norvegicus (Norway rat) | IC50 | 0.3200 | 1 | 1 |
Drugs with Activation Measurements
N1-Benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-chlorophenylcarboxamide (calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity.Journal of medicinal chemistry, , Aug-24, Volume: 49, Issue:17, 2006
Discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines as calcium-sensing receptor antagonists.Bioorganic & medicinal chemistry letters, , Dec-15, Volume: 15, Issue:24, 2005