malic acid has been researched along with Hyperglycemia in 4 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alloxan and oxidative stress, which have been detected in livers of laboratory animals shortly after in vivo alloxan administration, cause in vitro mitochondrial dysfunction, thus questioning alloxan diabetes as an acceptable model for type 1 diabetes, a model that cannot legitimately be used to investigate mitochondrial metabolism in a diabetic state." | 7.77 | Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes? ( Alvarez-Bustamante, JA; Rendon, DA, 2011) |
| "Alloxan and oxidative stress, which have been detected in livers of laboratory animals shortly after in vivo alloxan administration, cause in vitro mitochondrial dysfunction, thus questioning alloxan diabetes as an acceptable model for type 1 diabetes, a model that cannot legitimately be used to investigate mitochondrial metabolism in a diabetic state." | 3.77 | Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes? ( Alvarez-Bustamante, JA; Rendon, DA, 2011) |
| "Mice with juvenile visceral steatosis (JVS) develop remarkable cardiac hypertrophy and exhibit an increased number of mitochondria in their heart." | 1.32 | Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis. ( Arakaki, N; Higuti, T; Himeda, T; Kuwajima, M; Morokami, K; Shibata, H; Suenaga, M, 2003) |
| "At the end of anoxia, hyperglycemic cats exhibited significantly higher cortical lactate and glucose levels but similarly reduced high-energy phosphate concentrations compared to normoglycemic cats." | 1.27 | Hyperglycemia preserves brain mitochondrial respiration during anoxia. ( Myers, RE; Wagner, KR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rendon, DA | 1 |
| Alvarez-Bustamante, JA | 1 |
| Suenaga, M | 1 |
| Arakaki, N | 1 |
| Morokami, K | 1 |
| Himeda, T | 1 |
| Shibata, H | 1 |
| Kuwajima, M | 1 |
| Higuti, T | 1 |
| Nishikawa, T | 1 |
| Edelstein, D | 1 |
| Du, XL | 1 |
| Yamagishi, S | 1 |
| Matsumura, T | 1 |
| Kaneda, Y | 1 |
| Yorek, MA | 1 |
| Beebe, D | 1 |
| Oates, PJ | 1 |
| Hammes, HP | 1 |
| Giardino, I | 1 |
| Brownlee, M | 1 |
| Wagner, KR | 1 |
| Myers, RE | 1 |
4 other studies available for malic acid and Hyperglycemia
| Article | Year |
|---|---|
Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes?
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease | 2011 |
Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis.
Topics: Adenosine Triphosphatases; Animals; Blotting, Western; Cardiomegaly; Cytochromes; Disease Models, An | 2003 |
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage.
Topics: Animals; Aspartic Acid; Blood Glucose; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; | 2000 |
Hyperglycemia preserves brain mitochondrial respiration during anoxia.
Topics: Animals; Brain; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cats; Glutamates; Glutamic Acid; | 1986 |