Page last updated: 2024-12-07
3-bromo-4,5-dihydroxybenzaldehyde
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
3-bromo-4,5-dihydroxybenzaldehyde: a natural antioxidant from red algae (e.g., Rhodomela confervoides, Polysiphonia morrowii, and Polysiphonia urceolata) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 85405 |
| CHEMBL ID | 401368 |
| SCHEMBL ID | 1005213 |
| MeSH ID | M0584219 |
Synonyms (32)
| Synonym |
|---|
| 16414-34-9 |
| nsc139675 |
| nsc-139675 |
| STK400015 |
| 3-bromo-4,5-dihydroxybenzaldehyde |
| CHEMBL401368 , |
| AKOS000269718 |
| nsc 139675 |
| unii-kc2j6hxj8s |
| einecs 240-463-8 |
| kc2j6hxj8s , |
| benzaldehyde,3-bromo-4,5-dihydroxy- |
| SS-4168 |
| FT-0620173 |
| SCHEMBL1005213 |
| MB00252 |
| 3-bromo-4,5-dihydroxy-benzaldehyde |
| 5-bromo-3,4-dihydroxybenzaldehyde |
| GVSGSHGXUXLQNS-UHFFFAOYSA-N |
| 5-bromoprotocatechualdehyde |
| benzaldehyde, 3-bromo-4,5-dihydroxy- |
| DTXSID30167711 |
| J-511903 |
| 5-bromoprotocatechualdehyde, aldrichcpr |
| D76360 |
| mfcd00016608 |
| Q63408581 |
| CS-0103468 |
| A882480 |
| bdbm50526044 |
| EN300-106071 |
| Z381416832 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Protein Targets (1)
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 (µMol) | 354.2000 | 0.0005 | 3.4984 | 9.7600 | AID1602020 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
Biological Processes (27)
Molecular Functions (12)
Ceullar Components (11)
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1602020 | Inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli using pNPP as substrate measured after 30 mins by spectrophotometric method | 2019 | European journal of medicinal chemistry, Mar-15, Volume: 166 | Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors. |
| AID319045 | DPPH radical scavenging activity | 2008 | Journal of natural products, Jan, Volume: 71, Issue:1 | Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity. |
| AID333151 | Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay | 2004 | Journal of natural products, Sep, Volume: 67, Issue:9 | In-vitro cytotoxic activities of the major bromophenols of the red alga Polysiphonia lanosa and some novel synthetic isomers. |
| AID333152 | Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay | 2004 | Journal of natural products, Sep, Volume: 67, Issue:9 | In-vitro cytotoxic activities of the major bromophenols of the red alga Polysiphonia lanosa and some novel synthetic isomers. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (13)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 20.10
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (20.10) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 13 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||