| Assay ID | Title | Year | Journal | Article |
|---|
| AID1709593 | Modulation of human amyloid beta (1 to 42) supramolecular organization assessed as reduction in 6E10 epitope binding site structure at 1 mM measured for 1 to 5 days by Western blot analysis | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298840 | Increase in alkaline phosphatase activity in human MG63 cells at 5 ug/mL after 24 hrs | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID298846 | Reduction of lipopolysaccharide stimulated PGE2 synthesis in mouse RAW 264.7 cells at 10 ug/mL | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID1709591 | Modulation of human amyloid beta (1 to 42) supramolecular assembly assessed as elongation of amyloid beta42 fibrils at <50 mM measured for 10 days by ThT dye based fluorescence spectrophotometry | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709599 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in AChE activity at 1 mM incubated for 1 day | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709600 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in insulin resistance by measuring reduction in Abeta-42-induced IRS1 phosphorylation at Ser612 residue at 1 mM incubated for 1 hr by immunoblot | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709598 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as inhibition of Abeta42-induced disruption of cell membrane by measuring reduction in Ca2+ influx at 1 mM incubated for 24 hrs by Calcein-AM dye based scanni | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709606 | Modulation of human amyloid beta (1 to 42) supramolecular organization at 0.4 mM by dynamic light scattering based analysis | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709604 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in inflammation by measuring decrease in Abeta-42-induced ANXA1 expression at 1 mM incubated for 1 hr in presence of insulin by immunoblot analys | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298843 | Increase of collagen synthesis in human MG63 cells after 7 days | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID1709595 | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 1 mM measured after 1 day by alamar blue assay | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709605 | Modulation of human amyloid beta (1 to 42) supramolecular organization assessed as reduction in amount of cytotoxic Abeta42 oligomers at 1 mM measured for 1 to 5 days by Western blot analysis | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298850 | Increase of mineralization in human MG63 cells after 7 days | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID298841 | Increase in alkaline phosphatase activity in human MG63 cells at 1000 ug/mL after 24 hrs | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID1709596 | Neuroprotective activity against Abeta-42-induced cytotoxicity in human SH-SY5Y cells assessed as increase in cell viability at 1 mM measured upto 5 days by alamar blue assay | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709602 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in inflammation by measuring decrease in Abeta-42-induced ANXA1 expression at 1 mM incubated for 1 hr by immunoblot analysis | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709597 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as inhibition of Abeta42-induced disruption of cell membrane by measuring reduction in Ca2+ influx at 1 mM incubated for 24 hrs by Fluo-3AM dye based scanning | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298839 | Cytotoxicity against human MG63 cells up to 1000 ug/ml after 48 hrs by MTT assay | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID1709594 | Modulation of human amyloid beta (1 to 42) supramolecular organization assessed as reduction in antiparallel beta-sheets characteristic of cytotoxic Abeta42 aggregates at 1 mM measured for 5 days by CD spectrometry | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298842 | Effect on osteocalcin secretion in human MG63 cells after 4 days | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID298845 | Reduction of lipopolysaccharide stimulated IL1-beta synthesis in mouse RAW 264.7 cells | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID298844 | Inhibition of lipopolysaccharide stimulated TNFalpha synthesis in mouse RAW 264.7 cells | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID1709607 | Modulation of human amyloid beta (1 to 42) supramolecular organization assessed as prevalence of Abeta42 fibrils with parallel beta-sheets at 16 mM incubated for 5 days by ATR-FITR analysis | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298848 | Increase of collagen synthesis in human MG63 cells at 10 ug/mL relative to glucosamine | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| AID1709603 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in insulin resistance by measuring reduction in Abeta-42-induced IRS1 phosphorylation at Ser612 residue at 1 mM incubated for 1 hr in presence of | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709601 | Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in insulin resistance by measuring increase in AKT1 phosphorylation phosphorylation at Ser473 residue at 1 mM incubated for 1 hr by immunoblot an | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID1709592 | Modulation of human amyloid beta (1 to 42) supramolecular assembly assessed as elongation of amyloidbeta42 fibrils at 50 mM measured for 10 days by ThT dye based fluorescence spectrophotometry | 2021 | ACS medicinal chemistry letters, Apr-08, Volume: 12, Issue:4
| Glucosamine and Its Analogues as Modulators of Amyloid-β Toxicity. |
| AID298849 | Increase in alkaline phosphatase activity in human MG63 cells after 24 hrs | 2007 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 17, Issue:7
| Glucosamine sulfate promotes osteoblastic differentiation of MG-63 cells via anti-inflammatory effect. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |