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pentobarbital and Hyperglycemia

pentobarbital has been researched along with Hyperglycemia in 25 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"Since hyperglycemia was not abolished by adrenalectomy and/or hypophysectomy, a hypothesis is presented to explain how central accumulation of acetylcholine might cause hyperglycemia."5.25Evidence of central influences on blood glucose level: malathion hyperglycemia. ( Korner, M; Ramu, A, 1975)
" Rats with the same degree of hyperglycemia, treated after ischemia with pentobarbital (75-95 mg/kg) or diazepam (10-13 mg/kg), survived the observation period of 21 days and recovered, albeit incompletely."3.66Improvement of restitution from cerebral ischemia in hyperglycemic rats by pentobarbital or diazepam. ( Siemkowicz, E, 1980)
"Methylatropine pretreatment significantly increased islet blood flow during hypoglycemia by 181%."1.31Pancreatic islet blood flow in conscious rats during hyperglycemia and hypoglycemia. ( Goto, D; Iwase, M; Tashiro, K; Uchizono, Y; Yoshinari, M, 2001)
"The presence of cerebral hemorrhage after reperfusion was checked macroscopically and infarct volume with 2,3,5-triphenyltetrazolium staining."1.30Hyperglycemia and the vascular effects of cerebral ischemia. ( Betz, AL; Kawai, N; Keep, RF, 1997)
"Since hyperglycemia was not abolished by adrenalectomy and/or hypophysectomy, a hypothesis is presented to explain how central accumulation of acetylcholine might cause hyperglycemia."1.25Evidence of central influences on blood glucose level: malathion hyperglycemia. ( Korner, M; Ramu, A, 1975)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's4 (16.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
JILEK, L1
TROJAN, S1
HIETBRINK, BE1
YAM, KM1
REINERT, H1
WATTS, DT1
Garweg, G1
Siemkowicz, E1
Sieber, FE1
Brown, PR1
Wu, Y1
Koehler, RC1
Traystman, RJ1
Reyes Toso, CF1
Linares, LM1
Rodríguez, RR1
Kawai, N1
Keep, RF1
Betz, AL1
Iwase, M1
Tashiro, K1
Uchizono, Y1
Goto, D1
Yoshinari, M1
Ramu, A1
Korner, M1
Smythe, GA1
Edwards, SR1
Modak, AT1
Alderete, BE1
Lecomte, MJ1
Lefèbvre, P1
Luyckx, A1
Polacek, I1
Ouart, J1
Kansal, PC1
Buse, MG1
Duyckaerts, C1
Benke, A1
Kervran, A1
Girard, JR1
Anderson, DJ1
Shaw, GG1
Feldberg, W2
Shaligram, SV1
Aynsley-Green, A1
Biebuyck, JF1
Alberti, KG1
Gupta, KP1
Furner, RL1
Neville, ED1
Talarico, KS1
Feller, DD1
Vapaatalo, H1
Karppanen, H1

Other Studies

25 other studies available for pentobarbital and Hyperglycemia

ArticleYear
[Influences on resistance of the body against oligemia and ischemia of the CNS during the course of ontogenesis].
    Ceskoslovenska pediatrie, 1963, Volume: 18

    Topics: Aging; Central Nervous System; Chlorpromazine; Hyperglycemia; Hypoxia; Ischemia; Pentobarbital

1963
THE EFFECTS OF IONIZING RADIATIONS ON THE BIOCHEMISTRY OF MAMMALIAN TISSUES. I. STUDIES ON THE TOXICITY AND MECHANISM OF ACTION OF 2-MERCAPTOETHYLAMINE. REP NO. 51.
    Quarterly progress report. United States. Air Force. Radiation Laboratory, University of Chicago, 1964, Apr-15, Volume: 51

    Topics: Animals; Atropine; Cysteamine; Ergotamine; Hexamethonium Compounds; Hyperglycemia; Mammals; Mercapto

1964
URETHANE HYPERGLYCAEMIA AND HYPOTHALAMIC ACTIVATION.
    Nature, 1964, Nov-28, Volume: 204

    Topics: Adrenalectomy; Brain; Cats; Chloralose; Denervation; Dibenzylchlorethamine; Guanethidine; Hexamethon

1964
The effect of morphine and pentobarbital on ether hyperglycemia.
    Anesthesiology, 1952, Volume: 13, Issue:1

    Topics: Barbiturates; Ether; Ethers; Hyperglycemia; Morphine; Pentobarbital

1952
[The origin of experimental diabetic neuropathy. Comparative morphological investigations of the peripheral autonomic nervous system of the kidney and aorta in hyperglycemia, alloxan, ethionine and barbiturate poisoning in the dog].
    Deutsche Zeitschrift fur Nervenheilkunde, 1967, Volume: 192, Issue:2

    Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dogs; Ethionine; Hyperglycem

1967
Improvement of restitution from cerebral ischemia in hyperglycemic rats by pentobarbital or diazepam.
    Acta neurologica Scandinavica, 1980, Volume: 61, Issue:6

    Topics: Animals; Blood Glucose; Diazepam; Hyperglycemia; Ischemic Attack, Transient; Male; Pentobarbital; Ra

1980
Cerebral blood flow responsivity to CO2 in anesthetized chronically diabetic dogs.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: Animals; Blood Glucose; Carbon Dioxide; Cerebrovascular Circulation; Diabetes Mellitus, Experimental

1993
Blood sugar concentrations during ketamine or pentobarbitone anesthesia in rats with or without alpha and beta adrenergic blockade.
    Medicina, 1995, Volume: 55, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Blood Gluc

1995
Hyperglycemia and the vascular effects of cerebral ischemia.
    Stroke, 1997, Volume: 28, Issue:1

    Topics: Anesthetics; Animals; Blood Glucose; Body Temperature; Cerebral Arteries; Cerebral Hemorrhage; Cereb

1997
Pancreatic islet blood flow in conscious rats during hyperglycemia and hypoglycemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:6

    Topics: 3-O-Methylglucose; Anesthesia; Animals; Atropine Derivatives; Color; Hyperglycemia; Hypnotics and Se

2001
Evidence of central influences on blood glucose level: malathion hyperglycemia.
    European journal of pharmacology, 1975, Volume: 32, Issue:1

    Topics: Acetylcholine; Adrenalectomy; Animals; Atropine; Blood Glucose; Brain; Cholinesterases; Depression,

1975
Suppression of central noradrenergic neuronal activity inhibits hyperglycemia.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: Animals; Blood Glucose; Brain; Deoxyglucose; Hyperglycemia; Hypothalamus, Middle; Injections, Intrav

1992
Mecamylamine, but not atropine, antagonizes nicotine-induced hyperglycemia and potentiation of hypnosis produced by pentobarbital in mice.
    Pharmacology, 1986, Volume: 32, Issue:1

    Topics: Animals; Atropine; Blood Glucose; Drug Synergism; Hyperglycemia; Hypnosis, Anesthetic; Male; Mecamyl

1986
[Insulinemia and maximal rate of tubular reabsorption of glucose in the anesthetized dog].
    Archives internationales de physiologie et de biochimie, 1972, Volume: 80, Issue:1

    Topics: Absorption; Anesthesia, Intravenous; Animals; Arteries; Blood Glucose; Body Weight; Catheterization;

1972
Effect of phenformin in hyperglycemic rats.
    Diabetes, 1974, Volume: 23, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Antagonism; Epinep

1974
The effect of adrenergic blocking agents on plasma insulin and blood glucose during urethan or epinephrine induced hyperglycemia.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:6

    Topics: Adrenalectomy; Animals; Blood Glucose; Epinephrine; Female; Hyperglycemia; Insulin; Islets of Langer

1967
[Role of catecholamines in hypoxia and hyperglycemia induced by injection of cystamine].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:2

    Topics: Adrenal Medulla; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose;

1971
[Effect of various intravenous anesthetics on glucose levels and acid-base status of the blood in alloxan diabetic rats].
    Der Anaesthesist, 1971, Volume: 20, Issue:9

    Topics: Acid-Base Equilibrium; Anesthetics; Animals; Bicarbonates; Blood Glucose; Carbon Dioxide; Diabetes M

1971
Glucose-induced increase of plasma insulin in the rat foetus in utero.
    The Journal of endocrinology, 1974, Volume: 62, Issue:3

    Topics: Age Factors; Animals; Blood Glucose; Female; Fetus; Gestational Age; Glucose; Hyperglycemia; Immune

1974
Hyperglycaemia produced by the polyamines spermine and spermidine.
    British journal of pharmacology, 1974, Volume: 52, Issue:2

    Topics: Animals; Cerebral Ventricles; Cisterna Magna; Female; Hyperglycemia; Injections; Injections, Intrave

1974
The hyperglycaemic effect of morphine.
    British journal of pharmacology, 1972, Volume: 46, Issue:4

    Topics: Analgesia; Animals; Blood Glucose; Catheterization; Cats; Cerebral Ventricles; Coloring Agents; Epin

1972
Anaesthesia and insulin secretion: the effects of diethyl ether, halothane, pentobarbitone sodium and ketamine hydrochloride on intravenous glucose tolerance and insulin secretion in the rat.
    Diabetologia, 1973, Volume: 9, Issue:4

    Topics: Anesthesia, General; Anesthetics; Animals; Blood Glucose; Ethyl Ethers; Fasting; Glucose Tolerance T

1973
Morphine hyperglycaemia.
    The Journal of physiology, 1974, Volume: 238, Issue:3

    Topics: Anesthesia; Animals; Blood Glucose; Brain Stem; Catheterization; Cats; Cerebral Ventricles; Consciou

1974
Effects of pentobarbital on plasma glucose and free fatty acids in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:1

    Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Hyperglycemia; Injections, Intraperitoneal; Male

1972
Blood glucose, serum GOT and tissue catecholamines in rats after combined ethanol-tranquilizer administration.
    Agents and actions, 1970, Volume: 1, Issue:4

    Topics: Adrenal Glands; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Catecholamines; Chlormet

1970