Compounds > 4b,5,9b,10-tetrahydroindeno(1,2-b)indole
Page last updated: 2024-09-25

4b,5,9b,10-tetrahydroindeno(1,2-b)indole

Description

4b,5,9b,10-tetrahydroindeno(1,2-b)indole: RN refers to (cis)-isomer; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID131642
SCHEMBL ID277613
MeSH IDM0239605

Synonyms (6)

Synonym
4b,5,9b,10-tetrahydroindeno(1,2-b)indole
133571-34-3
ccris 7245
4b,5,9b,10-tetrahydroindeno[1,2-b]indole
SCHEMBL277613
DTXSID50928189

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
indole[no description available]medium10indole;
polycyclic heteroarene		Escherichia coli metabolite
malondialdehyde[no description available]medium10dialdehydebiomarker
acetaminophen[no description available]medium10acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
olanzapine[no description available]medium10benzodiazepine;
N-arylpiperazine;
N-methylpiperazine		antiemetic;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
serotonin uptake inhibitor
benzo(a)pyrene[no description available]medium11ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Autoimmune Diabetes0low10
Body Weight0low10
Cancer of Skin0medium11
Cancer of the Skin0medium11
Diabetes Mellitus0low10
Diabetes Mellitus, Adult-Onset0low10
Diabetes Mellitus, Brittle0low10
Diabetes Mellitus, Insulin-Dependent0low10
Diabetes Mellitus, Insulin-Dependent, 10low10
Diabetes Mellitus, Juvenile-Onset0low10
Diabetes Mellitus, Ketosis-Prone0low10
Diabetes Mellitus, Ketosis-Resistant0low10
Diabetes Mellitus, Maturity-Onset0low10
Diabetes Mellitus, Non Insulin Dependent0low10
Diabetes Mellitus, Non-Insulin-Dependent0low10
Diabetes Mellitus, Noninsulin Dependent0low10
Diabetes Mellitus, Noninsulin-Dependent0low10
Diabetes Mellitus, Slow-Onset0low10
Diabetes Mellitus, Stable0low10
Diabetes Mellitus, Sudden-Onset0low10
Diabetes Mellitus, Type 10low10
Diabetes Mellitus, Type 20low10
Diabetes Mellitus, Type I0low10
Diabetes Mellitus, Type II0low10
Diabetes, Autoimmune0low10
Disease Exacerbation0low10
Disease Progression0low10
Hyperglycemia0low10
Hyperglycemia, Postprandial0low10
IDDM0low10
Insulin Resistance0low10
Insulin Sensitivity0low10
Insulin-Dependent Diabetes Mellitus 10low10
Juvenile-Onset Diabetes0low10
Maturity-Onset Diabetes0low10
Maturity-Onset Diabetes Mellitus0low10
MODY0low10
Neoplasms, Skin0medium11
NIDDM0low10
Noninsulin-Dependent Diabetes Mellitus0low10
Obesity0low10
Postprandial Hyperglycemia0low10
Skin Cancer0medium11
Skin Neoplasms0medium11
Type 1 Diabetes0low10
Type 1 Diabetes Mellitus0low10
Type 2 Diabetes0low10
Type 2 Diabetes Mellitus0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (1)

ArticleYear
Protection from olanzapine-induced metabolic toxicity in mice by acetaminophen and tetrahydroindenoindole.
International journal of obesity (2005), Volume: 34, Issue: 6		2010
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]