glyburide has been researched along with Hyperglycemia in 119 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fasiglifam/TAK-875, a selective GPR40 agonist, enhances glucose-stimulated insulin secretion and improves hyperglycemia." | 7.83 | Fasiglifam/TAK-875, a Selective GPR40 Agonist, Improves Hyperglycemia in Rats Unresponsive to Sulfonylureas and Acts Additively with Sulfonylureas. ( Ito, R; Matsuda, K; Miyawaki, K; Suzuki, M; Takeuchi, K; Tsujihata, Y, 2016) |
| " In the present study, the effects of sulfonylureas administered supraspinally on kainic acid (KA)-induced hippocampal neuronal cell death and hyperglycemia were studied in ICR mice." | 7.80 | Effect of tolbutamide, glyburide and glipizide administered supraspinally on CA3 hippocampal neuronal cell death and hyperglycemia induced by kainic acid in mice. ( Jung, JS; Kim, CH; Kim, SJ; Kim, SS; Lim, SM; Park, SH; Sim, YB; Suh, HW, 2014) |
| "Persistent hypoglycemia is a serious condition that is frequently reported in patients undergoing sulfonylurea treatment, often necessitating hospitalization in the event of overdose." | 5.42 | Pasireotide (SOM230) prevents sulfonylurea-induced hypoglycemia in rats. ( Schmid, HA, 2015) |
| "Urethane is a widely used anesthetic and yohimbine is a well-known alpha 2-adrenergic antagonist." | 5.28 | Effect of yohimbine on urethane-induced hyperglycemia in rats. ( Aisaka, K; Ishihara, T; Kihara, T; Koike, M; Kuroki, M, 1989) |
| "Both exenatide and glibenclamide gave a similar improvement of glycemic control, but only exenatide gave improvements of insulin resistance and beta-cell function, giving also a decrease of body weight and of inflammatory state." | 5.14 | Exenatide versus glibenclamide in patients with diabetes. ( Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Franzetti, IG; Gadaleta, G; Maffioli, P; Piccinni, MN; Querci, F; Ragonesi, PD; Salvadeo, SA, 2010) |
| "To investigate the relationship between insulin resistance, postprandial hyperglycemia, postprandial hyperlipidemia, and oxidative stress in type 2 diabetes, changes in postprandial glucose, triglyceride, and nitrotyrosine levels vs baseline after diet loading were examined in type 2 diabetic patients given pioglitazone (PG) or glibenclamide (GB)." | 5.12 | Effects of pioglitazone vs glibenclamide on postprandial increases in glucose and triglyceride levels and on oxidative stress in Japanese patients with type 2 diabetes. ( Itoh, Y; Mori, Y; Obata, T; Tajima, N, 2006) |
| " We compared the effects of two insulin secretagogues, repaglinide and glyburide, known to have different efficacy on postprandial hyperglycemia, on carotid intima-media thickness (CIMT) and markers of systemic vascular inflammation in type 2 diabetic patients." | 5.11 | Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus. ( Esposito, K; Giugliano, D; Marfella, R; Nappo, F, 2004) |
| " At presentation, the acute C-peptide response to glucagon in obese DKA patients was lower than in patients with hyperglycemia (P < 0." | 5.08 | Sulfonylurea treatment prevents recurrence of hyperglycemia in obese African-American patients with a history of hyperglycemic crises. ( Clark, WS; Steen, MT; Umpierrez, GE, 1997) |
| " Group I acted as the control, whereas groups II, III, IV, and V were considered experimental groups which received a single dosage (150 mg/kg body weight) of alloxan (ALX) intraperitoneally (i." | 4.12 | Co-administration of ( Kar, A; Panda, S; Sharma, N; Yadav, D, 2022) |
| " Outcomes of normoglycemic studies reveals insignificant glucose lowering effects however hyperglycemic studies (glucose challenge and Alloxan inducted hyperglycemia) demonstrates significant glucose lowering effect of Aseel date especially with 300mg/kg dose." | 3.85 | Report - Antidiabetic effects of native date fruit Aseel (Phoenix dactylifera L.) in normal and hyperglycemic rats. ( Afroz, S; Ahmed, S; Jamil, S; Khan, RA, 2017) |
| " Fasiglifam/TAK-875, a selective GPR40 agonist, enhances glucose-stimulated insulin secretion and improves hyperglycemia." | 3.83 | Fasiglifam/TAK-875, a Selective GPR40 Agonist, Improves Hyperglycemia in Rats Unresponsive to Sulfonylureas and Acts Additively with Sulfonylureas. ( Ito, R; Matsuda, K; Miyawaki, K; Suzuki, M; Takeuchi, K; Tsujihata, Y, 2016) |
| " In the present study, the effects of sulfonylureas administered supraspinally on kainic acid (KA)-induced hippocampal neuronal cell death and hyperglycemia were studied in ICR mice." | 3.80 | Effect of tolbutamide, glyburide and glipizide administered supraspinally on CA3 hippocampal neuronal cell death and hyperglycemia induced by kainic acid in mice. ( Jung, JS; Kim, CH; Kim, SJ; Kim, SS; Lim, SM; Park, SH; Sim, YB; Suh, HW, 2014) |
| "In a south Indian population with gestational diabetes, metformin was associated with better neonatal outcomes than glibenclamide." | 2.80 | Comparison of neonatal outcomes in women with gestational diabetes with moderate hyperglycaemia on metformin or glibenclamide--a randomised controlled trial. ( Abraham, A; Antonisamy, B; Beck, M; Benjamin, SJ; George, A; Jana, AK; Mathews, JE; Sam, D; Thomas, N, 2015) |
| "Diabetes mellitus type 2 with dyslipidemia is a common disease." | 2.77 | Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. ( Dabaghian, FH; Hajiaghaee, R; Huseini, HF; Kianbakht, S, 2012) |
| "This open label study included sixty type 2 diabetes mellitus patients divided into 3 groups, receiving sesame oil (n = 18), 5 mg/day (single dose) of glibenclamide (n = 20), or their combination (n = 22)." | 2.76 | Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus. ( Ali, A; Rao, R; Sambandam, G; Sankar, D, 2011) |
| "Patients with Type 2 diabetes aged ≥ 21 years with 2-h postprandial glucose levels ≥ 11." | 2.76 | Nateglinide provides tighter glycaemic control than glyburide in patients with Type 2 diabetes with prevalent postprandial hyperglycaemia. ( Bellomo Damato, A; Giorgino, F; Giorgino, R; Laviola, L; Stefanelli, G, 2011) |
| "Repaglinide was also associated with an increase in the AUC(60) and AUC(120) for insulin (+56%, +61%) and C-peptide (+41%, +36%)." | 2.76 | Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus. ( Bain, SC; Bodvarsdottir, TB; Bracken, RM; Deacon, CF; Dunseath, G; Holst, JJ; Lowe, GD; Luzio, S; Prior, SL; Rumley, A; Stephens, JW; Wareham, K, 2011) |
| "To evaluate the efficacy and safety of two dosage strengths of a single-tablet metformin-glibenclamide (glyburide) combination, compared with the respective monotherapies, in patients with Type 2 diabetes mellitus (DM) inadequately controlled by metformin monotherapy." | 2.70 | Improved glycaemic control with metformin-glibenclamide combined tablet therapy (Glucovance) in Type 2 diabetic patients inadequately controlled on metformin. ( Allavoine, T; Howlett, H; Lehert, P; Marre, M, 2002) |
| "026) was observed, at lower dosage (p = 0." | 2.67 | Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination. ( Hermann, LS; Melander, A; Scherstén, B, 1994) |
| "The management of diabetes mellitus is often complicated in patients with advanced cancer." | 2.40 | The management of diabetes in patients with advanced cancer. ( Poulson, J, 1997) |
| " The effect of drying conditions on the morphology, moisture content, hardness, dosage uniformity, surface characteristics, and drug release mechanism of glibenclamide from the matrices was systematically investigated." | 1.51 | Controlled release of glibenclamide from monolithic silica subdermal implants produced by the sol-gel process and its use for hyperglycaemia treatment in a murine model. ( Espinosa-Contreras, C; Flores-Cabrera, Y; Hernández-Abad, VJ; Marroquín-Segura, R; Mora-Guevara, JLA; Sánchez-González, EG, 2019) |
| "Persistent hypoglycemia is a serious condition that is frequently reported in patients undergoing sulfonylurea treatment, often necessitating hospitalization in the event of overdose." | 1.42 | Pasireotide (SOM230) prevents sulfonylurea-induced hypoglycemia in rats. ( Schmid, HA, 2015) |
| " Glycaemia values returned to normality only after suspension of escitalopram, despite antidiabetic dosage increase." | 1.39 | A case report on escitalopram-induced hyperglycaemia in a diabetic patient. ( Brasesco, PC; Fucile, C; Leone, S; Martelli, A; Mattioli, F; Milano, G; Zuccoli, ML, 2013) |
| "The study cohort consisted of type 2 diabetes mellitus patients (n = 80) on regular therapy with glibenclamide either alone or with concomitant metformin." | 1.37 | Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients. ( Adithan, C; Agrawal, A; Anichavezhi, D; Pradhan, SC; Rajan, S; Subrahmanyam, DK; Surendiran, A, 2011) |
| "Type 2 diabetes mellitus is the consequence of both insulin resistance and impaired insulin secretion." | 1.32 | Optimal glycemic control in type 2 diabetes mellitus: fasting and postprandial glucose in context. ( Abrahamson, MJ, 2004) |
| " The aqueous extract of Syzygium alternifolium at a dosage of 0." | 1.31 | Hypoglycemic and antihyperglycemic activity of Syzygium alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats. ( Rao, BK; Rao, CH, 2001) |
| "Patients with NIDDM have elevated [Ca2+]i levels in PMNLs." | 1.29 | Polymorphonuclear leukocytes in non-insulin-dependent diabetes mellitus: abnormalities in metabolism and function. ( Alexiewicz, JM; Klin, M; Kumar, D; Massry, SG; Smogorzewski, M, 1995) |
| "A 60-year-old obese woman with type II diabetes mellitus and hepatomegaly exhibited progression of steatosis to hepatitis and cirrhosis." | 1.29 | Remission of active diabetic hepatitis after correction of hyperglycemia. ( Tak, PP; ten Kate, FJ, 1993) |
| "Urethane is a widely used anesthetic and yohimbine is a well-known alpha 2-adrenergic antagonist." | 1.28 | Effect of yohimbine on urethane-induced hyperglycemia in rats. ( Aisaka, K; Ishihara, T; Kihara, T; Koike, M; Kuroki, M, 1989) |
| "During the hyperglycemic clamp in NIDDM subjects, the first-phase plasma insulin response was absent, and the second-phase insulin response was markedly impaired." | 1.27 | Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects. ( DeFronzo, RA; Groop, L; Groop, PH; Luzi, L; Melander, A; Ratheiser, K; Simonson, DC, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (20.17) | 18.7374 |
| 1990's | 20 (16.81) | 18.2507 |
| 2000's | 30 (25.21) | 29.6817 |
| 2010's | 40 (33.61) | 24.3611 |
| 2020's | 5 (4.20) | 2.80 |
| Authors | Studies |
|---|---|
| Shukla, P | 1 |
| Singh, AB | 2 |
| Srivastava, AK | 2 |
| Pratap, R | 1 |
| Dwivedi, AP | 1 |
| Kumar, S | 1 |
| Varshney, V | 1 |
| Sahu, DP | 1 |
| Sharma, N | 1 |
| Kar, A | 1 |
| Panda, S | 1 |
| Yadav, D | 1 |
| Berdugo, M | 2 |
| Delaunay, K | 1 |
| Naud, MC | 1 |
| Guegan, J | 1 |
| Moulin, A | 1 |
| Savoldelli, M | 1 |
| Picard, E | 1 |
| Radet, L | 1 |
| Jonet, L | 1 |
| Djerada, Z | 2 |
| Gozalo, C | 2 |
| Daruich, A | 1 |
| Beltrand, J | 2 |
| Jeanny, JC | 1 |
| Kermorvant-Duchemin, E | 1 |
| Crisanti, P | 1 |
| Polak, M | 2 |
| Behar-Cohen, F | 1 |
| Nazir, N | 1 |
| Zahoor, M | 1 |
| Ullah, R | 1 |
| Ezzeldin, E | 1 |
| Mostafa, GAE | 1 |
| Babaei, M | 1 |
| Alizadeh-Fanalou, S | 1 |
| Nourian, A | 1 |
| Yarahmadi, S | 1 |
| Farahmandian, N | 1 |
| Nabi-Afjadi, M | 1 |
| Alipourfard, I | 1 |
| Bahreini, E | 1 |
| Pires Mendes, C | 1 |
| Postal, BG | 1 |
| Silva Frederico, MJ | 1 |
| Gonçalves Marques Elias, R | 1 |
| Aiceles de Medeiros Pinto, V | 1 |
| da Fonte Ramos, C | 1 |
| Devantier Neuenfeldt, P | 1 |
| Nunes, RJ | 1 |
| Mena Barreto Silva, FR | 1 |
| Ezejiofor, AN | 1 |
| Igweze, ZN | 1 |
| Udowelle, NA | 1 |
| Orisakwe, OE | 1 |
| Sadri, H | 1 |
| Larki, NN | 1 |
| Kolahian, S | 1 |
| Neumann, U | 1 |
| Bührer, C | 1 |
| Blankenstein, O | 1 |
| Kühnen, P | 1 |
| Raile, K | 1 |
| Oridupa, OA | 1 |
| Ovwighose, NO | 1 |
| Saba, AB | 1 |
| Abdellatief, SA | 1 |
| Beheiry, RR | 1 |
| El-Mandrawy, SAM | 1 |
| Ahmed, S | 1 |
| Khan, RA | 1 |
| Jamil, S | 1 |
| Afroz, S | 1 |
| Indumathi, D | 1 |
| Sujithra, K | 1 |
| Srinivasan, S | 1 |
| Vinothkumar, V | 1 |
| Hernández-Abad, VJ | 1 |
| Sánchez-González, EG | 1 |
| Espinosa-Contreras, C | 1 |
| Marroquín-Segura, R | 1 |
| Mora-Guevara, JLA | 1 |
| Flores-Cabrera, Y | 1 |
| Shahreen, S | 1 |
| Banik, J | 1 |
| Hafiz, A | 1 |
| Rahman, S | 3 |
| Zaman, AT | 1 |
| Shoyeb, MA | 1 |
| Chowdhury, MH | 1 |
| Rahmatullah, M | 4 |
| Hossain, M | 1 |
| Mahmud, A | 1 |
| Sultana, N | 1 |
| Rahman, SM | 1 |
| Islam, MR | 1 |
| Khatoon, MS | 1 |
| Jahan, S | 1 |
| Islam, F | 1 |
| Haque, ME | 1 |
| Jahan, R | 2 |
| Hosseini, S | 1 |
| Jamshidi, L | 1 |
| Mehrzadi, S | 1 |
| Mohammad, K | 1 |
| Najmizadeh, AR | 1 |
| Alimoradi, H | 1 |
| Huseini, HF | 2 |
| Zuccoli, ML | 1 |
| Milano, G | 1 |
| Leone, S | 1 |
| Fucile, C | 1 |
| Brasesco, PC | 1 |
| Martelli, A | 1 |
| Mattioli, F | 1 |
| Kim, CH | 1 |
| Park, SH | 1 |
| Sim, YB | 1 |
| Kim, SS | 1 |
| Kim, SJ | 1 |
| Lim, SM | 1 |
| Jung, JS | 1 |
| Suh, HW | 1 |
| Omeh, YN | 1 |
| Onoja, SO | 1 |
| Ezeja, MI | 1 |
| Okwor, PO | 1 |
| Brereton, MF | 1 |
| Iberl, M | 1 |
| Shimomura, K | 1 |
| Zhang, Q | 1 |
| Adriaenssens, AE | 1 |
| Proks, P | 1 |
| Spiliotis, II | 1 |
| Dace, W | 1 |
| Mattis, KK | 1 |
| Ramracheya, R | 1 |
| Gribble, FM | 1 |
| Reimann, F | 1 |
| Clark, A | 1 |
| Rorsman, P | 1 |
| Ashcroft, FM | 1 |
| Schmid, HA | 1 |
| George, A | 1 |
| Mathews, JE | 1 |
| Sam, D | 1 |
| Beck, M | 1 |
| Benjamin, SJ | 1 |
| Abraham, A | 1 |
| Antonisamy, B | 1 |
| Jana, AK | 1 |
| Thomas, N | 1 |
| Ito, R | 1 |
| Tsujihata, Y | 1 |
| Suzuki, M | 1 |
| Miyawaki, K | 1 |
| Matsuda, K | 1 |
| Takeuchi, K | 1 |
| Rabbone, I | 1 |
| Barbetti, F | 1 |
| Marigliano, M | 1 |
| Bonfanti, R | 1 |
| Piccinno, E | 1 |
| Ortolani, F | 1 |
| Ignaccolo, G | 1 |
| Maffeis, C | 1 |
| Confetto, S | 1 |
| Cerutti, F | 1 |
| Zanfardino, A | 1 |
| Iafusco, D | 1 |
| Tashakori-Sabzevar, F | 1 |
| Ramezani, M | 2 |
| Hosseinzadeh, H | 2 |
| Parizadeh, SM | 1 |
| Movassaghi, AR | 1 |
| Ghorbani, A | 1 |
| Mohajeri, SA | 1 |
| Wang, LP | 1 |
| Jiang, Y | 1 |
| Yang, H | 1 |
| Peng, C | 1 |
| Zhang, C | 1 |
| Tao, X | 1 |
| Xie, HH | 1 |
| Bouazza, N | 1 |
| Busiah, K | 1 |
| Urien, S | 1 |
| Treluyer, JM | 1 |
| Hashimoto, Y | 1 |
| Dateki, S | 1 |
| Hirose, M | 1 |
| Satomura, K | 1 |
| Sawada, H | 1 |
| Mizuno, H | 1 |
| Sugihara, S | 1 |
| Maruyama, K | 1 |
| Urakami, T | 1 |
| Sugawara, H | 1 |
| Shirai, K | 1 |
| Yorifuji, T | 1 |
| Kinoshita, H | 1 |
| Matsuda, N | 1 |
| Kaba, H | 1 |
| Hatakeyama, N | 1 |
| Azma, T | 1 |
| Nakahata, K | 1 |
| Kuroda, Y | 1 |
| Tange, K | 1 |
| Iranami, H | 1 |
| Hatano, Y | 1 |
| Simard, JM | 1 |
| Yurovsky, V | 1 |
| Tsymbalyuk, N | 1 |
| Melnichenko, L | 1 |
| Ivanova, S | 1 |
| Gerzanich, V | 1 |
| Del Guerra, S | 2 |
| D'Aleo, V | 2 |
| Lupi, R | 2 |
| Masini, M | 1 |
| Bugliani, M | 1 |
| Boggi, U | 1 |
| Filipponi, F | 1 |
| Marchetti, P | 2 |
| Adeneye, AA | 2 |
| Adeyemi, OO | 1 |
| McGill, JB | 1 |
| Derosa, G | 1 |
| Maffioli, P | 1 |
| Salvadeo, SA | 1 |
| Ferrari, I | 1 |
| Ragonesi, PD | 1 |
| Querci, F | 1 |
| Franzetti, IG | 1 |
| Gadaleta, G | 1 |
| Ciccarelli, L | 1 |
| Piccinni, MN | 1 |
| D'Angelo, A | 1 |
| Cicero, AF | 1 |
| Kochar, IP | 1 |
| Kulkarni, KP | 1 |
| Dreval', AV | 1 |
| Cheporeva, ON | 1 |
| Red'kin, IuA | 1 |
| Misnikova, IV | 1 |
| Gupta, R | 1 |
| Sharma, AK | 1 |
| Dobhal, MP | 1 |
| Sharma, MC | 1 |
| Gupta, RS | 1 |
| Sankar, D | 1 |
| Ali, A | 1 |
| Sambandam, G | 1 |
| Rao, R | 1 |
| Groves, C | 1 |
| Tancredi, M | 1 |
| McCarthy, M | 1 |
| Bellomo Damato, A | 1 |
| Stefanelli, G | 1 |
| Laviola, L | 1 |
| Giorgino, R | 1 |
| Giorgino, F | 1 |
| Sen, S | 1 |
| Roy, M | 1 |
| Chakraborti, AS | 1 |
| Surendiran, A | 1 |
| Pradhan, SC | 1 |
| Agrawal, A | 1 |
| Subrahmanyam, DK | 1 |
| Rajan, S | 1 |
| Anichavezhi, D | 1 |
| Adithan, C | 1 |
| Agbaje, EO | 1 |
| Olagunju, JA | 1 |
| Ročić, B | 1 |
| Znaor, A | 1 |
| Ročić, P | 1 |
| Weber, D | 1 |
| Vučić Lovrenčić, M | 1 |
| Stephens, JW | 1 |
| Bodvarsdottir, TB | 1 |
| Wareham, K | 1 |
| Prior, SL | 1 |
| Bracken, RM | 1 |
| Lowe, GD | 1 |
| Rumley, A | 1 |
| Dunseath, G | 1 |
| Luzio, S | 1 |
| Deacon, CF | 1 |
| Holst, JJ | 1 |
| Bain, SC | 1 |
| Reza, H | 1 |
| Haq, WM | 1 |
| Das, AK | 1 |
| Kianbakht, S | 1 |
| Hajiaghaee, R | 1 |
| Dabaghian, FH | 1 |
| Zhu, L | 1 |
| Cortes, P | 1 |
| Hassett, C | 1 |
| Taube, DW | 1 |
| Yee, J | 1 |
| Adebajo, AC | 1 |
| Ayoola, MD | 1 |
| Odediran, SA | 1 |
| Aladesanmi, AJ | 1 |
| Schmidt, TJ | 1 |
| Verspohl, EJ | 1 |
| Marre, M | 2 |
| Howlett, H | 3 |
| Lehert, P | 2 |
| Allavoine, T | 2 |
| Danaei, AR | 1 |
| Bukhalo, M | 1 |
| Zeitouni, NC | 1 |
| Cheney, RT | 1 |
| Garber, A | 1 |
| Blonde, L | 2 |
| Cornes, M | 1 |
| Faglia, E | 1 |
| Abrahamson, MJ | 1 |
| Riddle, MC | 1 |
| Esposito, K | 1 |
| Giugliano, D | 1 |
| Nappo, F | 1 |
| Marfella, R | 1 |
| Sorimachi, T | 1 |
| Fujii, Y | 1 |
| Tsuchiya, N | 1 |
| Saito, M | 1 |
| Mori, Y | 2 |
| Kitahara, Y | 1 |
| Miura, K | 1 |
| Mine, T | 1 |
| Tajima, N | 2 |
| Joyal, S | 1 |
| Henry, D | 1 |
| Davidson, JA | 1 |
| Scheen, AJ | 1 |
| Howlett, HC | 1 |
| Charpentier, G | 1 |
| Riveline, JP | 1 |
| Dardari, D | 1 |
| Varroud-Vial, M | 1 |
| Itoh, Y | 1 |
| Obata, T | 1 |
| Schoenfelder, T | 1 |
| Cirimbelli, TM | 1 |
| Citadini-Zanette, V | 1 |
| Codner, E | 1 |
| Flanagan, SE | 1 |
| Ugarte, F | 1 |
| García, H | 1 |
| Vidal, T | 1 |
| Ellard, S | 1 |
| Hattersley, AT | 1 |
| Anand, P | 1 |
| Murali, KY | 1 |
| Tandon, V | 1 |
| Chandra, R | 1 |
| Murthy, PS | 1 |
| Bhattacharya, SK | 1 |
| Shastri, S | 1 |
| Mahajan, P | 1 |
| Madhu, SV | 1 |
| Tripathi, AK | 1 |
| Rauniar, GP | 1 |
| Das, BP | 1 |
| Paudel, KR | 1 |
| Zuurbier, CJ | 1 |
| Keijzers, PJ | 1 |
| Koeman, A | 1 |
| Van Wezel, HB | 1 |
| Hollmann, MW | 1 |
| Alexiewicz, JM | 1 |
| Kumar, D | 1 |
| Smogorzewski, M | 1 |
| Klin, M | 1 |
| Massry, SG | 1 |
| Hermann, LS | 1 |
| Scherstén, B | 1 |
| Melander, A | 2 |
| Raz, I | 2 |
| Gilhar, D | 2 |
| Hoffman, A | 2 |
| Fischer, Y | 1 |
| Casu, A | 1 |
| Camogliano, L | 1 |
| Tak, PP | 1 |
| ten Kate, FJ | 1 |
| Paterson, AJ | 1 |
| Lamey, PJ | 1 |
| Lewis, MA | 1 |
| Nolan, A | 1 |
| Rademaker, M | 1 |
| Jaber, LA | 1 |
| Lewis, NJ | 1 |
| Slaughter, RL | 1 |
| Neale, AV | 1 |
| Malaisse, WJ | 1 |
| Lebrun, P | 1 |
| Sener, A | 1 |
| el-Kashef, HA | 1 |
| Salem, HA | 1 |
| Said, SA | 1 |
| Elmazar, MM | 1 |
| Clark, HE | 1 |
| Matthews, DR | 1 |
| Shigemori, K | 1 |
| Ishizaki, T | 1 |
| Matsukawa, S | 1 |
| Sakai, A | 1 |
| Nakai, T | 1 |
| Miyabo, S | 1 |
| Umpierrez, GE | 1 |
| Clark, WS | 1 |
| Steen, MT | 1 |
| Poulson, J | 1 |
| Piccolo, I | 1 |
| Sterzi, R | 1 |
| Thiella, G | 1 |
| Mooradian, AD | 1 |
| Thurman, JE | 1 |
| Pari, L | 1 |
| Maheswari, JU | 1 |
| Monnier, L | 1 |
| McFarlane, SI | 1 |
| Chaiken, RL | 1 |
| Hirsch, S | 1 |
| Harrington, P | 1 |
| Lebovitz, HE | 1 |
| Banerji, MA | 1 |
| Sriram, U | 1 |
| Rao, BK | 1 |
| Rao, CH | 1 |
| Fex, G | 1 |
| Lernmark, A | 2 |
| Boyd, K | 1 |
| Boreham, C | 1 |
| Andrews, WJ | 1 |
| Hadden, DR | 1 |
| Mourre, C | 1 |
| Smith, ML | 1 |
| Siesjö, BK | 1 |
| Lazdunski, M | 1 |
| Abu-Jayyab, AR | 1 |
| el-Denshary, ES | 1 |
| el-Sawaf, HA | 1 |
| al-Bekairi, AM | 1 |
| Aisaka, K | 1 |
| Kihara, T | 1 |
| Koike, M | 1 |
| Kuroki, M | 1 |
| Ishihara, T | 1 |
| Shapiro, ET | 1 |
| Van Cauter, E | 1 |
| Tillil, H | 1 |
| Given, BD | 1 |
| Hirsch, L | 1 |
| Beebe, C | 1 |
| Rubenstein, AH | 1 |
| Polonsky, KS | 1 |
| Groop, L | 1 |
| Luzi, L | 1 |
| Groop, PH | 1 |
| Ratheiser, K | 1 |
| Simonson, DC | 1 |
| DeFronzo, RA | 1 |
| Mascardo, RN | 1 |
| Watling, SM | 1 |
| Lusk, JA | 1 |
| Olefsky, JM | 1 |
| Kolterman, OG | 1 |
| Hosker, JP | 1 |
| Burnett, MA | 1 |
| Davies, EG | 1 |
| Harris, EA | 1 |
| Turner, RC | 1 |
| Lorch, E | 1 |
| Gey, KF | 1 |
| Sommer, P | 1 |
| Beyer, J | 1 |
| Cordes, U | 1 |
| Sell, G | 1 |
| Schöffling, K | 1 |
| Artini, D | 1 |
| Abbiati, R | 1 |
| Orsini, G | 1 |
| Parenti, MA | 1 |
| Bloch, K | 1 |
| Daturi, S | 1 |
| Mandelli, V | 1 |
| Hellman, B | 9 |
| Orofino, G | 1 |
| Bigotti, A | 1 |
| Idahl, LA | 3 |
| Hurme, P | 1 |
| Wahlquist, Y | 1 |
| Sehlin, J | 5 |
| Täljedal, IB | 3 |
| Danielsson, A | 1 |
| Täljedal, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Glucose Lowering Therapies Including Dipeptidyl Peptidase-4 Inhibitor on Circulating Endothelial Progenitor Cells (EPCs) and Its Mobilising Factor Stromal Derived Factor-1α (SDF-1α) in Patients With Type 2 Diabetes[NCT02694575] | 241 participants (Actual) | Observational | 2015-03-01 | Completed | |||
| A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832] | 30 participants (Anticipated) | Interventional | 2016-09-21 | Completed | |||
| Impact of Pantoprazole on 24-H Glycemic Control and on Post-prandial Glucose Excursion Inpatients With Type 2 Diabetes[NCT02345239] | Phase 3 | 14 participants (Anticipated) | Interventional | 2015-02-28 | Not yet recruiting | ||
| FLAT-SUGAR: FLuctuATion Reduction With inSULin and Glp-1 Added togetheR[NCT01524705] | Phase 4 | 102 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Variability of Glucose Assessed in a Randomized Trial Comparing the Initiation of A Treatment Approach With Biosimilar Basal Insulin Analog Or a Titratable iGlarLixi combinatioN in Type 2 Diabetes Among South Asian Subjects (VARIATION 2 SA Trial)[NCT03819790] | Phase 4 | 119 participants (Actual) | Interventional | 2018-10-02 | Completed | ||
| Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes[NCT04943692] | Phase 3 | 500 participants (Anticipated) | Interventional | 2021-08-31 | Suspended (stopped due to Administrative decision of the investigation direction) | ||
| Safety and Efficacy of Metformin Glycinate vs Metformin Hydrochloride on Metabolic Control and Inflammatory Mediators in Type 2 Diabetes Patients[NCT01386671] | Phase 3 | 203 participants (Actual) | Interventional | 2014-06-30 | Completed | ||
| Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetics[NCT00065676] | Phase 2 | 24 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The change in the coefficient of variation (CV) of continuous glucose readings, as assessed by Continuous Glucose Monitoring (CGM) (NCT01524705)
Timeframe: At baseline, 6 months of intervention
| Intervention | percentage (Mean) |
|---|---|
| Insulin Glargine, Metformin, Exenatide | -2.43 |
| Insulin Glargine, Metformin, Prandial Insulin | 0.44 |
% of glycosylated hemoglobin in whole blood at 26 weeks (NCT01524705)
Timeframe: Baseline vs 26 weeks
| Intervention | % of HbA1C (Mean) |
|---|---|
| Insulin Glargine, Metformin, Exenatide | 7.1 |
| Insulin Glargine, Metformin, Prandial Insulin | 7.2 |
Severe hypoglycemia-documented glucose <50mg/dl (participant journal), and hypoglycemic attacks requiring hospitalization, or treatment by emergency personnel. (NCT01524705)
Timeframe: 26 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Insulin Glargine, Metformin, Exenatide | 0 |
| Insulin Glargine, Metformin, Prandial Insulin | 0 |
Weight in kg at 26 weeks minus weight at baseline. (NCT01524705)
Timeframe: Baseline vs 26 weeks
| Intervention | kg (Mean) |
|---|---|
| Insulin Glargine, Metformin, Exenatide | -4.8 |
| Insulin Glargine, Metformin, Prandial Insulin | 0.7 |
11 reviews available for glyburide and Hyperglycemia
| Article | Year |
|---|---|
Selecting among ADA/EASD tier 1 and tier 2 treatment options.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Dr | 2009 |
Influence of initial hyperglycaemia, weight and age on the blood glucose lowering efficacy and incidence of hypoglycaemic symptoms with a single-tablet metformin-glibenclamide therapy (Glucovance) in type 2 diabetes.
Topics: Age Factors; Aged; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dose-Response Relation | 2003 |
[Antidiabetic therapy in diabetic patients with coronary heart disease].
Topics: Administration, Oral; Coronary Disease; Delayed-Action Preparations; Diabetes Complications; Diabete | 2003 |
Timely initiation of basal insulin.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy, Combination | 2004 |
Tolerability profile of metformin/glibenclamide combination tablets (Glucovance): a new treatment for the management of type 2 diabetes mellitus.
Topics: Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 2004 |
Should postprandial hyperglycaemia in prediabetic and type 2 diabetic patients be treated?
Topics: Acarbose; Adult; Aged; Aged, 80 and over; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitu | 2006 |
The management of diabetes in patients with advanced cancer.
Topics: Blood Glucose; Carcinoma, Squamous Cell; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitu | 1997 |
Drug therapy of postprandial hyperglycaemia.
Topics: 1-Deoxynojirimycin; Acarbose; Amyloid; Carbamates; Diabetes Mellitus; Enzyme Inhibitors; Glucosamine | 1999 |
Is postprandial glucose a neglected cardiovascular risk factor in type 2 diabetes?
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucose Intolerance; Glyburide; Glycated Hemoglo | 2000 |
Post-prandial hyperglycemia and its implications in pregnancy and lipid abnormalities.
Topics: Female; Glyburide; Humans; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Postprandial Period; | 2001 |
The role of calcium in insulin secretion.
Topics: Animals; Butyrates; Calcium; Calcium Isotopes; Cyclic AMP; Glucose; Glyburide; Hyperglycemia; Insuli | 1973 |
19 trials available for glyburide and Hyperglycemia
| Article | Year |
|---|---|
Effects of Juglans regia L. leaf extract on hyperglycemia and lipid profiles in type two diabetic patients: a randomized double-blind, placebo-controlled clinical trial.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Glyca | 2014 |
Comparison of neonatal outcomes in women with gestational diabetes with moderate hyperglycaemia on metformin or glibenclamide--a randomised controlled trial.
Topics: Adult; Birth Injuries; Birth Weight; Diabetes, Gestational; Female; Fetal Macrosomia; Glyburide; Hum | 2015 |
Evaluation of the pharmacokinetics of glibenclamide tablet given, off label, orally to children suffering from neonatal syndromic hyperglycemia.
Topics: Administration, Oral; Blood Glucose; Child; Child, Preschool; Cytochrome P-450 CYP2C9; Dose-Response | 2016 |
Exenatide versus glibenclamide in patients with diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Mass Index; Body Weight; C-Reactive | 2010 |
[Correlation of HBA(1c) and postprandial glycemia during a standard breakfast test in patients with type 2 diabetes mellitus receiving glibenclamide].
Topics: Blood Glucose; Carbohydrate Metabolism; Combined Modality Therapy; Diabetes Mellitus, Type 2; Eating | 2010 |
Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus.
Topics: Antioxidants; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Food-Drug | 2011 |
Nateglinide provides tighter glycaemic control than glyburide in patients with Type 2 diabetes with prevalent postprandial hyperglycaemia.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cyclohexanes; Diabetes Mellitus, Type 2; Di | 2011 |
Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients.
Topics: Adult; Blood Glucose; C-Peptide; Creatine; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Gl | 2011 |
Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; | 2011 |
Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial.
Topics: Adult; Aloe; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Gels; Glyburide; Humans; Hyperc | 2012 |
Improved glycaemic control with metformin-glibenclamide combined tablet therapy (Glucovance) in Type 2 diabetic patients inadequately controlled on metformin.
Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blin | 2002 |
Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Carbamates; Carotid Artery Diseases; Cross-Sectional Studies | 2004 |
Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Carbamates; Carotid Artery Diseases; Cross-Sectional Studies | 2004 |
Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Carbamates; Carotid Artery Diseases; Cross-Sectional Studies | 2004 |
Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Carbamates; Carotid Artery Diseases; Cross-Sectional Studies | 2004 |
Durable efficacy of metformin/glibenclamide combination tablets (Glucovance) during 52 weeks of open-label treatment in type 2 diabetic patients with hyperglycaemia despite previous sulphonylurea monotherapy.
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide | 2004 |
Effects of pioglitazone vs glibenclamide on postprandial increases in glucose and triglyceride levels and on oxidative stress in Japanese patients with type 2 diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fatty Acids, Nones | 2006 |
Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therap | 1994 |
Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therap | 1994 |
Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therap | 1994 |
Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therap | 1994 |
Prolonged response to glibenclamide in NIDDM patients in a normoglycemic state.
Topics: Adult; Aged; Biological Availability; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Gly | 1994 |
The effect of stress on glycemic control in patients with type II diabetes during glyburide and glipizide therapy.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Femal | 1993 |
The effect of glimepiride on pancreatic beta-cell function under hyperglycaemic clamp and hyperinsulinaemic, euglycaemic clamp conditions in non-insulin-dependent diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Glucose Clamp Technique; G | 1996 |
Sulfonylurea treatment prevents recurrence of hyperglycemia in obese African-American patients with a history of hyperglycemic crises.
Topics: Adult; Black or African American; Black People; Blood Glucose; C-Peptide; Combined Modality Therapy; | 1997 |
89 other studies available for glyburide and Hyperglycemia
| Article | Year |
|---|---|
Chalcone based aryloxypropanolamines as potential antihyperglycemic agents.
Topics: Animals; Chalones; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Indicators a | 2007 |
Synthesis and antihyperglycemic activity of novel N-acyl-2-arylethylamines and N-acyl-3-coumarylamines.
Topics: Acylation; Animals; Blood Glucose; Coumaric Acids; Diabetes Mellitus, Experimental; Ethylamines; Hyp | 2008 |
Co-administration of
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucose | 2022 |
The antidiabetic drug glibenclamide exerts direct retinal neuroprotection.
Topics: Administration, Oral; Animals; Chlorocebus aethiops; Diabetes Mellitus, Experimental; Diabetic Retin | 2021 |
Curative Effect of Catechin Isolated from
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Antioxidants; Benzothiazoles; Biphenyl Compounds; Blood | 2020 |
Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with hydroalcoholic extract of Securigera Securidaca seeds, and Glibenclamide.
Topics: Animals; Blood Glucose; Drug Therapy, Combination; Ethanol; Fibroblast Growth Factors; Gene Expressi | 2021 |
Synthesis of a novel glibenclamide-pioglitazone hybrid compound and its effects on glucose homeostasis in normal and insulin-resistant rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glyburide; Home | 2021 |
Histopathological and biochemical assessments of Costus afer stem on alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Biomarkers; Body Weight; Costus; Diabetes Mellitus, Experimental; Glyburide; Hyper | 2017 |
Hypoglycemic and Hypolipidemic Effects of Leucine, Zinc, and Chromium, Alone and in Combination, in Rats with Type 2 Diabetes.
Topics: Animals; Blood Glucose; Chromium; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dietary Supp | 2017 |
Primary sulphonylurea therapy in a newborn with transient neonatal diabetes attributable to a paternal uniparental disomy 6q24 (UPD6).
Topics: Administration, Oral; Berlin; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Dr | 2018 |
Anti-Hyperglycaemic Effect of Cleome Rutidosperma in Alloxan-Induced Diabetic Albino Rats.
Topics: Animals; Blood Glucose; Cleome; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; G | 2017 |
Peppermint essential oil alleviates hyperglycemia caused by streptozotocin- nicotinamide-induced type 2 diabetes in rats.
Topics: Administration, Oral; Animals; Antioxidants; Diabetes Mellitus, Type 2; Free Radical Scavengers; Gly | 2017 |
Report - Antidiabetic effects of native date fruit Aseel (Phoenix dactylifera L.) in normal and hyperglycemic rats.
Topics: Alloxan; Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Fruit; Glyburide; Hype | 2017 |
Betanin exhibits significant potential as an antihyperglycemic and attenuating the glycoprotein components in streptozotocin-nicotinamide-induced experimental rats.
Topics: Animals; Betacyanins; Biomarkers; Body Weight; Combined Modality Therapy; Diabetes Mellitus, Experim | 2018 |
Controlled release of glibenclamide from monolithic silica subdermal implants produced by the sol-gel process and its use for hyperglycaemia treatment in a murine model.
Topics: Animals; Delayed-Action Preparations; Disease Models, Animal; Glyburide; Humidity; Hyperglycemia; Im | 2019 |
Antihyperglycemic activities of leaves of three edible fruit plants (Averrhoa carambola, Ficus hispida and Syzygium samarangense) of Bangladesh.
Topics: Animals; Bangladesh; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Ficus; Frui | 2012 |
Antihyperglycemic and antinociceptive activity evaluation of 'khoyer' prepared from boiling the wood of Acacia catechu in water.
Topics: Acacia; Acetic Acid; Analgesics; Animals; Aspirin; Bangladesh; Behavior, Animal; Blood Glucose; Diab | 2013 |
Evaluation of antihyperglycemic and antinociceptive activity of Xanthium indicum stem extract in Swiss albino mice.
Topics: Analgesics; Animals; Bangladesh; Blood Glucose; Drug Evaluation, Preclinical; Glucose Tolerance Test | 2013 |
A case report on escitalopram-induced hyperglycaemia in a diabetic patient.
Topics: Aged, 80 and over; Antidepressive Agents; Citalopram; Depression; Diabetes Mellitus; Drug Therapy, C | 2013 |
Effect of tolbutamide, glyburide and glipizide administered supraspinally on CA3 hippocampal neuronal cell death and hyperglycemia induced by kainic acid in mice.
Topics: Animals; Blood Glucose; CA3 Region, Hippocampal; Cell Death; Glipizide; Glyburide; Hyperglycemia; Hy | 2014 |
Subacute antidiabetic and in vivo antioxidant effects of methanolic extract of Bridelia micrantha (Hochst Baill) leaf on alloxan-induced hyperglycaemic rats.
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Dose-Respo | 2014 |
Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Electrophysiology; | 2014 |
Pasireotide (SOM230) prevents sulfonylurea-induced hypoglycemia in rats.
Topics: Animals; Dose-Response Relationship, Drug; Fasting; Glyburide; Hyperglycemia; Hypoglycemia; Male; Oc | 2015 |
Fasiglifam/TAK-875, a Selective GPR40 Agonist, Improves Hyperglycemia in Rats Unresponsive to Sulfonylureas and Acts Additively with Sulfonylureas.
Topics: Animals; Benzofurans; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Glucose Tolera | 2016 |
Successful treatment of young infants presenting neonatal diabetes mellitus with continuous subcutaneous insulin infusion before genetic diagnosis.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glyburide; Humans; H | 2016 |
Protective and hypoglycemic effects of celery seed on streptozotocin-induced diabetic rats: experimental and histopathological evaluation.
Topics: Alanine Transaminase; Animals; Apium; Aspartate Aminotransferases; Blood Glucose; Diabetes Mellitus, | 2016 |
Combination Therapy of Nifedipine and Sulphonylureas Exhibits a Mutual Antagonistic Effect on the Endothelial Cell Dysfunction Induced by Hyperglycemia Linked to Vascular Disease.
Topics: Antihypertensive Agents; Biphenyl Compounds; Cell Movement; Diabetic Angiopathies; Drug Synergism; E | 2016 |
Molecular and clinical features of K
Topics: Amino Acid Substitution; Congenital Hyperinsulinism; Diabetes Mellitus; DNA Mutational Analysis; Dru | 2017 |
Roles of phosphatidylinositol 3-kinase-Akt and NADPH oxidase in adenosine 5'-triphosphate-sensitive K+ channel function impaired by high glucose in the human artery.
Topics: Antihypertensive Agents; Arteries; Chromones; Cromakalim; Enzyme Inhibitors; Glucose; Glyburide; Hum | 2008 |
Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke.
Topics: Animals; ATP-Binding Cassette Transporters; Brain; Brain Ischemia; Cerebral Infarction; Data Interpr | 2009 |
Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide.
Topics: Aged; Analysis of Variance; Cells, Cultured; Female; Gliclazide; Glucose; Glyburide; Homeodomain Pro | 2009 |
Further evaluation of antihyperglycaemic activity of Hunteria umbellata (K. Schum) Hallier f. seed extract in experimental diabetes.
Topics: Animals; Apocynaceae; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Rel | 2009 |
Transient Neonatal Diabetes due to Kcnj11 Mutation.
Topics: Glyburide; Humans; Hyperglycemia; Infant; Insulin; Male; Mutation, Missense; Potassium Channels, Inw | 2010 |
Antidiabetic and antioxidant potential of β-sitosterol in streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Dose-Response Relat | 2011 |
INS VNTR class genotype and the function of isolated human islets.
Topics: Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Gene | 2011 |
Ameliorative effects of glycyrrhizin on streptozotocin-induced diabetes in rats.
Topics: Animals; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Free Radicals; Fruct | 2011 |
Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients.
Topics: Alleles; Amplified Fragment Length Polymorphism Analysis; Aryl Hydrocarbon Hydroxylases; Cohort Stud | 2011 |
Metformin: an effective attenuator of risperidone-induced insulin resistance hyperglycemia and dyslipidemia in rats.
Topics: Animals; Antipsychotic Agents; Blood Glucose; Disease Models, Animal; Dyslipidemias; Glyburide; Huma | 2011 |
Anti-hyperglycemic and antinociceptive activity of methanol leaf and stem extract of Nypa fruticans Wurmb.
Topics: Acetic Acid; Analgesics; Animals; Arecaceae; Aspirin; Blood Glucose; Glucose; Glyburide; Hyperglycem | 2011 |
Glibenclamide induces collagen IV catabolism in high glucose-stimulated mesangial cells.
Topics: Animals; Cells, Cultured; Collagen Type IV; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diabet | 2012 |
Evaluation of ethnomedical claim III: anti-hyperglycemic activities of Gongronema latifolium root and stem.
Topics: Animals; Apocynaceae; Blood Glucose; Cell Line, Tumor; Chromatography, Liquid; Drug Evaluation, Prec | 2013 |
Antihyperglycaemic effect and acute toxicity of Securigera Securidaca L. seed extracts in mice.
Topics: Administration, Oral; Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Respons | 2002 |
Leukocytoclastic vasculitis induced by use of glyburide: a case of possible cross-reaction of a sulfonamide and a sulfonylurea.
Topics: Adult; Diuretics; Drug Interactions; Glyburide; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Su | 2003 |
Optimal glycemic control in type 2 diabetes mellitus: fasting and postprandial glucose in context.
Topics: Antihypertensive Agents; Blood Glucose; Blood Glucose Self-Monitoring; Carbamates; Diabetes Mellitus | 2004 |
Striatal hyperintensity on T1-weighted magnetic resonance images and high-density signal on CT scans obtained in patients with hyperglycemia and no involuntary movement. Report of two cases.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Caudate Nucleus; Corpus Striatum; Dyskinesias; Female | 2004 |
Role of early insulin secretion in postglucose-loading hyperglycaemia and postfat-loading hyperlipidaemia: comparing nateglinide and glibenclamide for acute effects on insulin secretion in OLETF rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Type 2; Dietary Fats; Gene | 2004 |
Acute effect of Trema micrantha (Ulmaceae) on serum glucose levels in normal and diabetic rats.
Topics: Animals; Blood Glucose; Brazil; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; G | 2006 |
Sulfonylurea treatment in young children with neonatal diabetes: dealing with hyperglycemia, hypoglycemia, and sick days.
Topics: Blood Glucose; Child, Preschool; Diabetes Mellitus; Female; Glyburide; Health Status; Humans; Hyperg | 2007 |
Preliminary studies on antihyperglycemic effect of aqueous extract of Brassica nigra (L.) Koch in streptozotocin induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hyperglycemia; Hypoglycemic Agen | 2007 |
Polymorphonuclear leukocyte function in type-2 diabetes mellitus patients and its correlation with glycaemic control.
Topics: Adult; Aged; Blood Glucose; Chronic Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Fema | 2007 |
Anesthesia's effects on plasma glucose and insulin and cardiac hexokinase at similar hemodynamics and without major surgical stress in fed rats.
Topics: Adrenergic alpha-Antagonists; Anesthetics; Animals; Blood Glucose; Body Weight; Cytosol; Decanoic Ac | 2008 |
Polymorphonuclear leukocytes in non-insulin-dependent diabetes mellitus: abnormalities in metabolism and function.
Topics: Adenosine Triphosphate; Adult; Aged; Calcium; Cytosol; Diabetes Mellitus, Type 2; Female; Glyburide; | 1995 |
The effect of hyperglycaemia on the absorption of glibenclamide in patients with non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hyperglycemia; Intestinal Absorpt | 1994 |
Glibenclamide partly reverses monesin inhibition of insulin secretion, in vivo.
Topics: Animals; Blood Glucose; Female; Glyburide; Hyperglycemia; Insulin; Insulin Secretion; Monensin; Rats | 1993 |
Remission of active diabetic hepatitis after correction of hyperglycemia.
Topics: Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Hepatitis; Humans; Hypergly | 1993 |
Pemphigus vulgaris precipitated by glibenclamide therapy.
Topics: Aged; Azathioprine; Candidiasis, Oral; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Fluconazole | 1993 |
Modulation of the insulinotropic action of glibenclamide and glimepiride by nutrient secretagogues in pancreatic islets from normoglycemic and hyperglycemic rats.
Topics: Animals; B-Lymphocytes; Calcium; Carbon Dioxide; Diabetes Mellitus, Type 2; Glucose; Glyburide; Hype | 1993 |
Effect of praziquantel on serum glucose and insulin levels in normal and hyperglycemic rats.
Topics: Animals; Blood Glucose; Glucose Tolerance Test; Glyburide; Hyperglycemia; Hypoglycemic Agents; Insul | 1996 |
Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Glyburide; Hyperglycemia; Hypoglycemic Agents; | 1996 |
Chorea in hyperglycemia.
Topics: Aged; Aged, 80 and over; Brain; Chorea; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Gl | 1998 |
Hypoglycaemic effect of Musa sapientum L. in alloxan-induced diabetic rats.
Topics: Animals; Blood Glucose; Chloroform; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dru | 1999 |
Near-normoglycaemic remission in African-Americans with Type 2 diabetes mellitus is associated with recovery of beta cell function.
Topics: Aged; Biomarkers; Black or African American; Black People; Blood Glucose; C-Peptide; Combined Modali | 2001 |
Hypoglycemic and antihyperglycemic activity of Syzygium alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; | 2001 |
Effects of insulin secretagogues on phospholipid metabolism in pancreatic beta-cells.
Topics: Animals; Arginine; Glucose; Glyburide; Hyperglycemia; Insulin; Islets of Langerhans; Leucine; Mice; | 1975 |
Correction of fasting hyperglycaemia with insulin or sulphonylurea lowers fasting ketone levels, but does not alter resting or post-glucose energy expenditure in non insulin dependent diabetes. Differences between the OGTT and the glucose clamp.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Energy Metabolism; Fasting; Female; Glucose; Gl | 1991 |
Brain ischemia alters the density of binding sites for glibenclamide, a specific blocker of ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Brain; Glyburide; Hyperglycemia; Ischemic Attack, Transient; Male; | 1990 |
Counteraction of nifedipine-induced hyperglycaemia by metformin.
Topics: Animals; Glyburide; Hyperglycemia; Male; Metformin; Nifedipine; Rats | 1990 |
Effect of yohimbine on urethane-induced hyperglycemia in rats.
Topics: Animals; Glyburide; Hyperglycemia; Male; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Urethan | 1989 |
Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glyburide; Humans; Hyperglycem | 1989 |
Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gastric Inhibitory Polypeptide; Gl | 1987 |
The effects of hyperglycemia on the directed migration of wounded endothelial cell monolayers.
Topics: Animals; Cattle; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vasc | 1988 |
Glyburide and possible Somogyi effect.
Topics: Aged; Aged, 80 and over; Blood Glucose; Female; Glyburide; Humans; Hyperglycemia; Hypoglycemia | 1988 |
Clinical, cellular, and physiologic effects of glyburide in non-insulin-dependent diabetes mellitus.
Topics: Biological Transport; Diabetes Mellitus, Type 2; Drug Administration Schedule; Glucose; Glyburide; H | 1985 |
Longitudinal evaluation of the effects of sulfonylurea therapy in subjects with type II diabetes mellitus.
Topics: Adipose Tissue; Blood Glucose; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; Glyburide | 1985 |
Sulphonylurea therapy doubles B-cell response to glucose in type 2 diabetic patients.
Topics: Aged; Blood Glucose; C-Peptide; Chlorpropamide; Diabetes Mellitus, Type 2; Glucose; Glyburide; Human | 1985 |
[Glibornuride, a new high-effective antidiabetic agent. Pharmacological and biochemical comparative studies in various animal species and animal experimental models].
Topics: Administration, Oral; Animals; Blood Glucose; Camphanes; Chemical Phenomena; Chemistry; Cholesterol; | 1972 |
[Extrapancreatic effects of sulfonylurea compounds. 3. Studies on the additional blood sugar decreasing and antilipolytic effect of tolbutamide, glibornuride, and glibenclamide on completely pancreatectomized dogs, chronically treated with insulin during
Topics: Animals; Blood Glucose; Camphanes; Dogs; Fatty Acids, Nonesterified; Glyburide; Glycerol; Hyperglyce | 1972 |
Pharmacodynamic aspects of two sulphonylurea derivatives glipizide and glibenclamide.
Topics: Administration, Oral; Animals; Blood Glucose; Cyclohexanes; Dogs; Glucose; Glyburide; Hyperglycemia; | 1973 |
Factors affecting the uptake of glibenclamide in microdissected pancreatic islets rich in beta-cells.
Topics: Albumins; Animals; Carbon Radioisotopes; Cell Membrane Permeability; Female; Glyburide; Hyperglycemi | 1974 |
Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells.
Topics: Animals; Binding Sites; Drug Synergism; Female; Glyburide; Hyperglycemia; Insulin; Insulin Secretion | 1974 |
[Morphological changes in the pancreas and islands of Langerhans in rats during induced hyperglycemia and hypoglycemia].
Topics: Animals; Diabetes Mellitus; Glyburide; Hyperglycemia; Hypoglycemia; Islets of Langerhans; Pancreas; | 1974 |
Pancreatic -cell function and content of 6-phosphogluconate.
Topics: Animals; Butyrates; Calcium; Cyclic AMP; Epinephrine; Female; Gluconates; Glucose; Glucosephosphates | 1971 |
Effects of glucose and other modifiers of insulin release on the oxidative metabolism of amino acids in micro-dissected pancreatic islets.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Citrates; Cyclic AMP; Depression, Chemical | 1971 |
Pancreatic islet levels of citrate under conditions of stimulated and inhibited insulin release.
Topics: Animals; Butyrates; Calcium; Caprylates; Citrates; Cyclic AMP; Dose-Response Relationship, Drug; Epi | 1972 |
Transport and storage of 5-hydroxytryptamine in pancreatic -cells.
Topics: Animals; Biological Transport; Carbon Isotopes; Chromatography, Gel; Diazoxide; Glucose; Glyburide; | 1972 |
Transport of L-leucine and D-leucine into pancreatic -cells with reference to the mechanisms of amino acid-induced insulin release.
Topics: Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cells; Extracellular Space; Glyburide; | 1972 |
Uptake and oxidation of glutamic acid in mammalian pancreatic islets.
Topics: Alanine; Animals; Arginine; Carbon Isotopes; Female; Galactose; Glucose; Glutamates; Glyburide; Hype | 1972 |
Levels of -ketoglutarate and glutamate in stimulated pancreatic -cells.
Topics: Animals; Carbutamide; Chemical Phenomena; Chemistry; Depression, Chemical; Diazoxide; Female; Fluoro | 1970 |
Uptake of alanine, arginine and leucine by mammalian pancreatic beta-cells.
Topics: Alanine; Animals; Arginine; Carbon Isotopes; Diazoxide; Fructose; Glucose; Glyburide; Hyperglycemia; | 1971 |