zimeldine and Hyperglycemia

zimeldine has been researched along with Hyperglycemia* in 1 studies

Other Studies

1 other study(ies) available for zimeldine and Hyperglycemia

Article	Year
Involvement of serotonin in zimelidine-induced hyperglycemia in mice. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:11 Effects of a selective serotonin reuptake inhibitor, zimelidine, on plasma glucose was studied in mice. Zimelidine dose-dependently induced hyperglycemia, although it did not change insulin levels. To determine the involvement of the serotonergic system in zimelidine-induced hyperglycemia, effects of the 5-HT depleter p-chlorophenylalanine(pCPA) were examined. pCPA significantly reduced zimelidine-induced hyperglycemia. This suggests that zimelidine-induced hyperglycemia is mediated by the serotonergic system through its 5-HT reuptake inhibition. Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Fenclonine; Hyperglycemia; Insulin; Male; Mice; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Time Factors; Zimeldine	1999

Article

Year

Involvement of serotonin in zimelidine-induced hyperglycemia in mice.

Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:11

Effects of a selective serotonin reuptake inhibitor, zimelidine, on plasma glucose was studied in mice. Zimelidine dose-dependently induced hyperglycemia, although it did not change insulin levels. To determine the involvement of the serotonergic system in zimelidine-induced hyperglycemia, effects of the 5-HT depleter p-chlorophenylalanine(pCPA) were examined. pCPA significantly reduced zimelidine-induced hyperglycemia. This suggests that zimelidine-induced hyperglycemia is mediated by the serotonergic system through its 5-HT reuptake inhibition.

Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Fenclonine; Hyperglycemia; Insulin; Male; Mice; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Time Factors; Zimeldine

1999