ofloxacin has been researched along with Hyperglycemia in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare rates of hypoglycemia and hyperglycemia among elderly hospitalized patients with normal blood glucose concentrations at baseline who were receiving either gatifloxacin or levofloxacin, and to determine if appropriateness of their doses, according to their package inserts, was associated with hypoglycemia or hyperglycemia." | 7.74 | Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients. ( Graves, J; Lodise, T; Lomaestro, B; Miller, C; Mohr, JF; Smith, RP, 2007) |
| "To compare rates of hypoglycemia and hyperglycemia among elderly hospitalized patients with normal blood glucose concentrations at baseline who were receiving either gatifloxacin or levofloxacin, and to determine if appropriateness of their doses, according to their package inserts, was associated with hypoglycemia or hyperglycemia." | 3.74 | Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients. ( Graves, J; Lodise, T; Lomaestro, B; Miller, C; Mohr, JF; Smith, RP, 2007) |
| "To assess the prevalence of dysglycemia (hypoglycemia or hyperglycemia) associated with oral levofloxacin and gatifloxacin therapy in an outpatient setting, and to determine the characteristics of patients who developed dysglycemia while receiving either fluoroquinolone." | 3.74 | Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting. ( LaPlante, KL; Mersfelder, TL; Quilliam, BJ; Ward, KE, 2008) |
| " In the first, case patients were persons treated in the hospital for hypoglycemia after outpatient treatment with a macrolide, a second-generation cephalosporin, or a respiratory fluoroquinolone (gatifloxacin, levofloxacin, moxifloxacin, or ciprofloxacin)." | 3.73 | Outpatient gatifloxacin therapy and dysglycemia in older adults. ( Dresser, L; Juurlink, DN; Kopp, A; Low, DE; Mamdani, MM; Park-Wyllie, LY; Shah, BR; Stukel, TA; Stumpo, C, 2006) |
| " Diphenhydramine (1 mg/kg) antagonized the hyperglycemia induced by 300 mg/kg of levofloxacin." | 3.73 | Effect of levofloxacin on serum glucose concentration in rats. ( Ishiwata, Y; Itoga, Y; Yasuhara, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohr, JF | 2 |
| McKinnon, PS | 1 |
| Peymann, PJ | 1 |
| Kenton, I | 1 |
| Septimus, E | 1 |
| Okhuysen, PC | 1 |
| Tailor, SA | 1 |
| Simor, AE | 1 |
| Cornish, W | 1 |
| Phillips, EJ | 1 |
| Knowles, S | 1 |
| Rachlis, A | 1 |
| Park-Wyllie, LY | 1 |
| Juurlink, DN | 1 |
| Kopp, A | 1 |
| Shah, BR | 1 |
| Stukel, TA | 1 |
| Stumpo, C | 1 |
| Dresser, L | 1 |
| Low, DE | 1 |
| Mamdani, MM | 1 |
| Ishiwata, Y | 1 |
| Itoga, Y | 1 |
| Yasuhara, M | 1 |
| Catero, M | 1 |
| Lodise, T | 1 |
| Graves, J | 1 |
| Miller, C | 1 |
| Lomaestro, B | 1 |
| Smith, RP | 1 |
| LaPlante, KL | 1 |
| Mersfelder, TL | 1 |
| Ward, KE | 1 |
| Quilliam, BJ | 1 |
1 review available for ofloxacin and Hyperglycemia
| Article | Year |
|---|---|
Dysglycemia and fluoroquinolones: are you putting patients at risk?
Topics: Adolescent; Adult; Aza Compounds; Bacterial Infections; Blood Glucose; Ciprofloxacin; Dose-Response | 2007 |
7 other studies available for ofloxacin and Hyperglycemia
| Article | Year |
|---|---|
Levofloxacin and glycaemic disorders. Diabetic patients: beware.
Topics: Canada; Diabetes Mellitus; Humans; Hyperglycemia; Hypoglycemia; Levofloxacin; Ofloxacin | 2008 |
A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Ceftriaxone; Ciprofloxacin; Fe | 2005 |
Glucose homeostasis abnormalities and gatifloxacin.
Topics: Aza Compounds; Fluoroquinolones; Gatifloxacin; Glucose; Homeostasis; Humans; Hyperglycemia; Hypoglyc | 2006 |
Outpatient gatifloxacin therapy and dysglycemia in older adults.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Case-Control Studies; Cephalosporin | 2006 |
Effect of levofloxacin on serum glucose concentration in rats.
Topics: Adrenal Medulla; Animals; Anti-Bacterial Agents; Blood Glucose; Diphenhydramine; Dose-Response Relat | 2006 |
Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cohort Studies; Dose-Response Relationship, Drug; Fe | 2007 |
Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Creatinin | 2008 |