probucol has been researched along with Hyperglycemia in 4 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol has a more pronounced health benefit than high-dose CoQ(10) supplementation and uniquely restores CoQ(9) content in mutant kidney." | 1.37 | Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice. ( Chen, JY; Clarke, CF; Falk, MJ; Gasser, DL; Horyn, O; King, R; Maltzman, JS; Marbois, B; Nakamaru-Ogiso, E; Nissim, I; Okwuego, E; Ostrovsky, J; Peng, M; Polyak, E; Xie, LX; Zhang, Z, 2011) |
| "Probucol can suppress cell proliferation, down-regulate mRNA and protein levels of TGF-beta1 and CTGF in HMCs treated with high glucose." | 1.36 | Janus kinase 2/signal transducers and activators of transcription signal inhibition regulates protective effects of probucol on mesangial cells treated with high glucose. ( Du, J; Fan, Q; Feng, J; Liu, X; Luo, J; Ma, J; Wang, J; Wang, L; Yao, L; Zhou, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, J | 1 |
| Wang, L | 1 |
| Liu, X | 1 |
| Zhou, H | 1 |
| Fan, Q | 1 |
| Luo, J | 1 |
| Yao, L | 1 |
| Wang, J | 1 |
| Feng, J | 1 |
| Ma, J | 1 |
| Falk, MJ | 1 |
| Polyak, E | 1 |
| Zhang, Z | 1 |
| Peng, M | 1 |
| King, R | 1 |
| Maltzman, JS | 1 |
| Okwuego, E | 1 |
| Horyn, O | 1 |
| Nakamaru-Ogiso, E | 1 |
| Ostrovsky, J | 1 |
| Xie, LX | 1 |
| Chen, JY | 1 |
| Marbois, B | 1 |
| Nissim, I | 1 |
| Clarke, CF | 1 |
| Gasser, DL | 1 |
| Lee, IK | 1 |
| Koya, D | 1 |
| Ishi, H | 1 |
| Kanoh, H | 1 |
| King, GL | 1 |
| Shimizu, H | 1 |
| Uehara, Y | 1 |
| Shimomura, Y | 1 |
| Tanaka, Y | 1 |
| Kobayashi, I | 1 |
4 other studies available for probucol and Hyperglycemia
| Article | Year |
|---|---|
Janus kinase 2/signal transducers and activators of transcription signal inhibition regulates protective effects of probucol on mesangial cells treated with high glucose.
Topics: Antioxidants; Cell Line; Cell Proliferation; Connective Tissue Growth Factor; Diabetic Nephropathies | 2010 |
Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice.
Topics: Albuminuria; Alkyl and Aryl Transferases; Animals; Anticholesteremic Agents; Antioxidants; Energy Me | 2011 |
d-Alpha-tocopherol prevents the hyperglycemia induced activation of diacylglycerol (DAG)-protein kinase C (PKC) pathway in vascular smooth muscle cell by an increase of DAG kinase activity.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Cells, Cultured; Diacylglycerol Kinase; Diglycerides; Gl | 1999 |
Probucol attenuated hyperglycemia in multiple low-dose streptozotocin-induced diabetic mice.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Flow Cytometry; Gluco | 1991 |