niacinamide has been researched along with Hyperglycemia in 64 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In our patients, nicotinamide effectively decreased phosphorus, increased high-density lipoprotein, and caused thrombocytopenia." | 9.15 | Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial. ( Abbaspour, MR; Belladi Musavi, SS; Ghorbani, A; Hayati, F; Lashkarara, GR; Shahbazian, H; Zafar Mohtashami, A, 2011) |
| "Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia." | 8.02 | Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats. ( Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN, 2021) |
| " The present study aimed to elucidate the association between stress and the PARP pathway by using resveratrol (RSV) and nicotinamide (NAM, PARP inhibitor) to treat diabetic cataract." | 8.02 | Biochemical Evidence Indicates the Preventive Effect of Resveratrol and Nicotinamide in the Treatment of STZ-induced Diabetic Cataract. ( Bodakhe, SH; Singh, A, 2021) |
| "The present study was hypothesized to investigate the hepatoprotective nature of resveratrol in averting hyperglycemia-mediated oxidative stress by measuring extent of oxidant stress and levels of proinflammatory cytokines and antioxidant competence in the hepatic tissues of streptozotocin-nicotinamide-induced diabetic rats." | 7.76 | Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats. ( Palsamy, P; Sivakumar, S; Subramanian, S, 2010) |
| " Thus, the present study was aimed to investigate the hypothesis that oral administration of resveratrol attenuates hyperglycemia, proinflammatory cytokines and antioxidant competence and protects beta-cell ultrastructure in streptozotocin-nicotinamide-induced diabetic rats." | 7.76 | Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats. ( Palsamy, P; Subramanian, S, 2010) |
| " Five or ten microgram/animal of 6-AN produced a marked hyperglycemia, lowered glycogen content in the brain and liver, and reduced the adrenal epinephrine content." | 7.66 | Centrally mediated hyperglycemia by 6-aminonicotinamide. ( Baba, A; Baba, T; Iwata, H; Matsuda, T, 1978) |
| "In our patients, nicotinamide effectively decreased phosphorus, increased high-density lipoprotein, and caused thrombocytopenia." | 5.15 | Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial. ( Abbaspour, MR; Belladi Musavi, SS; Ghorbani, A; Hayati, F; Lashkarara, GR; Shahbazian, H; Zafar Mohtashami, A, 2011) |
| "Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia." | 4.02 | Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats. ( Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN, 2021) |
| " The present study aimed to elucidate the association between stress and the PARP pathway by using resveratrol (RSV) and nicotinamide (NAM, PARP inhibitor) to treat diabetic cataract." | 4.02 | Biochemical Evidence Indicates the Preventive Effect of Resveratrol and Nicotinamide in the Treatment of STZ-induced Diabetic Cataract. ( Bodakhe, SH; Singh, A, 2021) |
| "The present study was hypothesized to investigate the hepatoprotective nature of resveratrol in averting hyperglycemia-mediated oxidative stress by measuring extent of oxidant stress and levels of proinflammatory cytokines and antioxidant competence in the hepatic tissues of streptozotocin-nicotinamide-induced diabetic rats." | 3.76 | Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats. ( Palsamy, P; Sivakumar, S; Subramanian, S, 2010) |
| " Thus, the present study was aimed to investigate the hypothesis that oral administration of resveratrol attenuates hyperglycemia, proinflammatory cytokines and antioxidant competence and protects beta-cell ultrastructure in streptozotocin-nicotinamide-induced diabetic rats." | 3.76 | Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats. ( Palsamy, P; Subramanian, S, 2010) |
| " Five or ten microgram/animal of 6-AN produced a marked hyperglycemia, lowered glycogen content in the brain and liver, and reduced the adrenal epinephrine content." | 3.66 | Centrally mediated hyperglycemia by 6-aminonicotinamide. ( Baba, A; Baba, T; Iwata, H; Matsuda, T, 1978) |
| "The relationship between the dose of intravenously administered streptozotocin (a N-nitroso derivative of glucosamine) and the diabetogenic response has been explored by use of the following indices of diabetogenic action: serum glucose, urine volume, and glycosuria, ketonuria, serum immunoreactive insulin (IRI), and pancreatic IRI content." | 3.65 | Diabetogenic action of streptozotocin: relationship of dose to metabolic response. ( Junod, A; Lambert, AE; Renold, AE; Stauffacher, W, 1969) |
| "Hyperglycemia was induced in rats by the administration of nicotinamide and streptozotocin." | 1.51 | Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats. ( Detante, O; Diekhorst, L; Díez-Tejedor, E; Fuentes, B; Gómez-de Frutos, MC; Gutiérrez-Fernández, M; Jolkkonen, J; Laso-García, F; Martínez-Arroyo, A; Moisan, A; Otero-Ortega, L, 2019) |
| "Hyperglycemia is one of the severe adverse drug reactions (ADRs) in cancer treatment." | 1.46 | Glycaemic adverse drug reactions from anti-neoplastics used in treating pancreatic cancer. ( He, J; Jia, B; Yan, J; Yang, J, 2017) |
| "Periodontitis was induced by ligature around the left mandibular first molar 1 wk after injection." | 1.40 | Diabetic characteristics and alveolar bone loss in streptozotocin- and streptozotocin-nicotinamide-treated rats with periodontitis. ( Bak, EJ; Cha, JH; Choi, SH; Kim, JH; Lee, DE; Yoo, YJ, 2014) |
| " Long-term administration of guava leaf extracts increased the plasma insulin level and glucose utilization in diabetic rats." | 1.35 | Effect of guava (Psidium guajava Linn.) leaf soluble solids on glucose metabolism in type 2 diabetic rats. ( Cheng, FC; Shen, SC; Wu, NJ, 2008) |
| " The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i." | 1.32 | Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004) |
| "Treatment with niacinamide (nicotinamide), may have been of benefit since all problems were resolved within three months of ingestion." | 1.26 | Accidental ingestion of Vacor rodenticide: the symptoms and sequelae in a 25-month-old child. ( Johnson, D; Kubic, P; Levitt, C, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (21.88) | 18.7374 |
| 1990's | 6 (9.38) | 18.2507 |
| 2000's | 9 (14.06) | 29.6817 |
| 2010's | 30 (46.88) | 24.3611 |
| 2020's | 5 (7.81) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YC | 1 |
| Chiu, YM | 1 |
| Dai, ZK | 1 |
| Wu, BN | 2 |
| Abdelkader, NF | 1 |
| Ibrahim, SM | 1 |
| Moustafa, PE | 1 |
| Elbaset, MA | 1 |
| Tykhonenko, T | 1 |
| Guzyk, M | 1 |
| Tykhomyrov, A | 1 |
| Korsa, V | 1 |
| Yanitska, L | 1 |
| Kuchmerovska, T | 1 |
| Lee, SR | 1 |
| Jeong, SH | 1 |
| Mukae, M | 1 |
| Kim, SY | 1 |
| Ko, JW | 1 |
| Kwun, HJ | 1 |
| Hong, EJ | 1 |
| Singh, A | 1 |
| Bodakhe, SH | 1 |
| Ovalle-Magallanes, B | 1 |
| Déciga-Campos, M | 1 |
| Mata, R | 1 |
| Abdullah, KM | 2 |
| Qais, FA | 1 |
| Ahmad, I | 1 |
| Naseem, I | 2 |
| Nakatsu, Y | 1 |
| Kokubo, H | 1 |
| Bumdelger, B | 1 |
| Yoshizumi, M | 1 |
| Yamamotoya, T | 1 |
| Matsunaga, Y | 1 |
| Ueda, K | 1 |
| Inoue, Y | 1 |
| Inoue, MK | 1 |
| Fujishiro, M | 1 |
| Kushiyama, A | 1 |
| Ono, H | 1 |
| Sakoda, H | 1 |
| Asano, T | 1 |
| Abdellatief, SA | 1 |
| Beheiry, RR | 1 |
| El-Mandrawy, SAM | 1 |
| Yang, J | 1 |
| Jia, B | 1 |
| Yan, J | 1 |
| He, J | 1 |
| Shen, KP | 1 |
| Lin, HL | 1 |
| Yen, HW | 1 |
| Hsieh, SL | 1 |
| An, LM | 1 |
| Indumathi, D | 1 |
| Sujithra, K | 1 |
| Srinivasan, S | 1 |
| Vinothkumar, V | 1 |
| Alam, MM | 1 |
| Iqbal, Z | 1 |
| Balakrishnan, BB | 1 |
| Krishnasamy, K | 1 |
| Mayakrishnan, V | 1 |
| Selvaraj, A | 1 |
| El-Beih, NM | 1 |
| Ramadan, G | 1 |
| El-Husseiny, EA | 1 |
| Hussein, AM | 1 |
| Gómez-de Frutos, MC | 1 |
| Laso-García, F | 1 |
| Diekhorst, L | 1 |
| Otero-Ortega, L | 1 |
| Fuentes, B | 1 |
| Jolkkonen, J | 1 |
| Detante, O | 1 |
| Moisan, A | 1 |
| Martínez-Arroyo, A | 1 |
| Díez-Tejedor, E | 1 |
| Gutiérrez-Fernández, M | 1 |
| Volchegorskiĭ, IA | 1 |
| Rassokhina, LM | 1 |
| Ermakova, SG | 1 |
| Miroshnichenko, IIu | 1 |
| Annadurai, T | 1 |
| Thomas, PA | 1 |
| Geraldine, P | 1 |
| Kim, JH | 1 |
| Lee, DE | 1 |
| Choi, SH | 1 |
| Cha, JH | 1 |
| Bak, EJ | 1 |
| Yoo, YJ | 1 |
| Nayak, Y | 1 |
| Hillemane, V | 1 |
| Daroji, VK | 1 |
| Jayashree, BS | 1 |
| Unnikrishnan, MK | 1 |
| Gounden, S | 1 |
| Phulukdaree, A | 1 |
| Moodley, D | 1 |
| Chuturgoon, A | 1 |
| Liu, CY | 1 |
| Hsu, YJ | 1 |
| Chien, YW | 1 |
| Cha, TL | 1 |
| Tsao, CW | 1 |
| Lekshmi, RK | 1 |
| Rajesh, R | 1 |
| Mini, S | 1 |
| Furman, BL | 1 |
| Arya, A | 3 |
| Al-Obaidi, MM | 1 |
| Karim, RB | 1 |
| Taha, H | 2 |
| Khan, AK | 1 |
| Shahid, N | 1 |
| Sayem, AS | 2 |
| Looi, CY | 2 |
| Mustafa, MR | 2 |
| Mohd, MA | 2 |
| Ali, HM | 1 |
| Adam, SH | 1 |
| Giribabu, N | 1 |
| Rao, PV | 1 |
| Panichayupakaranant, P | 1 |
| Korla, PK | 1 |
| Salleh, N | 1 |
| Xin, Y | 1 |
| Jiang, X | 1 |
| Wang, Y | 1 |
| Su, X | 1 |
| Sun, M | 1 |
| Zhang, L | 1 |
| Tan, Y | 1 |
| Wintergerst, KA | 1 |
| Li, Y | 2 |
| Polakof, S | 1 |
| Dardevet, D | 1 |
| Lyan, B | 1 |
| Mosoni, L | 1 |
| Gatineau, E | 1 |
| Martin, JF | 1 |
| Pujos-Guillot, E | 1 |
| Mazur, A | 1 |
| Comte, B | 1 |
| Palsamy, P | 3 |
| Subramanian, S | 3 |
| Shen, SC | 1 |
| Cheng, FC | 1 |
| Wu, NJ | 1 |
| Tahara, A | 1 |
| Matsuyama-Yokono, A | 1 |
| Nakano, R | 1 |
| Someya, Y | 1 |
| Hayakawa, M | 1 |
| Shibasaki, M | 1 |
| Sivakumar, S | 1 |
| Novelli, M | 2 |
| Bonamassa, B | 1 |
| Masini, M | 1 |
| Funel, N | 1 |
| Canistro, D | 1 |
| De Tata, V | 1 |
| Martano, M | 1 |
| Soleti, A | 2 |
| Campani, D | 1 |
| Paolini, M | 2 |
| Masiello, P | 2 |
| Lee, J | 1 |
| Yee, ST | 1 |
| Kim, JJ | 1 |
| Choi, MS | 1 |
| Kwon, EY | 1 |
| Seo, KI | 1 |
| Lee, MK | 1 |
| Shahbazian, H | 1 |
| Zafar Mohtashami, A | 1 |
| Ghorbani, A | 1 |
| Abbaspour, MR | 1 |
| Belladi Musavi, SS | 1 |
| Hayati, F | 1 |
| Lashkarara, GR | 1 |
| Zhang, S | 1 |
| Cai, G | 1 |
| Fu, B | 1 |
| Feng, Z | 1 |
| Ding, R | 1 |
| Bai, X | 1 |
| Liu, W | 1 |
| Zhuo, L | 1 |
| Sun, L | 1 |
| Liu, F | 1 |
| Chen, X | 1 |
| Cheah, SC | 1 |
| Larsen, MO | 1 |
| Gotfredsen, CF | 1 |
| Wilken, M | 1 |
| Carr, RD | 1 |
| Pørksen, N | 1 |
| Rolin, B | 1 |
| Matsumoto, T | 1 |
| Wakabayashi, K | 1 |
| Kobayashi, T | 1 |
| Kamata, K | 1 |
| Murugan, P | 1 |
| Pari, L | 1 |
| D'Aleo, V | 1 |
| Lupi, R | 1 |
| Marchetti, P | 1 |
| Kaul, CL | 1 |
| Talwalker, PK | 1 |
| Grewal, RS | 1 |
| Johnson, D | 1 |
| Kubic, P | 1 |
| Levitt, C | 1 |
| Ueki, M | 3 |
| Yasunami, Y | 3 |
| Motoyama, K | 2 |
| Funakoshi, A | 1 |
| Ikeda, S | 3 |
| Tanaka, M | 2 |
| Arima, T | 1 |
| Nagai, T | 1 |
| Nagata, N | 1 |
| Ono, J | 1 |
| Zhu, M | 2 |
| Noma, Y | 1 |
| Mizuno, A | 1 |
| Sano, T | 1 |
| Shima, K | 2 |
| Wong, KK | 1 |
| Ogino, T | 1 |
| Murakami, T | 1 |
| Kuwajima, M | 1 |
| Piercy, V | 1 |
| Toseland, CD | 1 |
| Turner, NC | 1 |
| Sakakibara, Y | 1 |
| Mitha, AP | 1 |
| Ayoub, IA | 1 |
| Ogilvy, CS | 1 |
| Maynard, KI | 1 |
| Johnson, JT | 1 |
| Kaplan, ML | 1 |
| Leveille, GA | 1 |
| Baba, A | 1 |
| Baba, T | 1 |
| Matsuda, T | 1 |
| Iwata, H | 1 |
| Sandler, S | 1 |
| Andersson, A | 1 |
| Schultz, G | 1 |
| Senft, G | 1 |
| Losert, W | 1 |
| Schacht, U | 1 |
| Junod, A | 1 |
| Lambert, AE | 1 |
| Stauffacher, W | 1 |
| Renold, AE | 1 |
| Lison, H | 1 |
| Sassine, A | 2 |
| Rechencq, E | 1 |
| Bourgeois, JM | 2 |
| Macabies, J | 1 |
| Berlet, HH | 1 |
| Dulin, WE | 1 |
| Wyse, BM | 1 |
| Schein, PS | 1 |
| Alberti, KG | 1 |
| Williamson, DH | 1 |
| Gunnarsson, R | 1 |
| Berne, C | 1 |
| Hellerström, C | 1 |
1 trial available for niacinamide and Hyperglycemia
| Article | Year |
|---|---|
Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial.
Topics: Administration, Oral; Adult; Aged; Diarrhea; Double-Blind Method; Female; Humans; Hyperglycemia; Hyp | 2011 |
63 other studies available for niacinamide and Hyperglycemia
| Article | Year |
|---|---|
Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats.
Topics: Animals; Antioxidants; Behavior, Animal; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide | 2021 |
Inosine mitigated diabetic peripheral neuropathy via modulating GLO1/AGEs/RAGE/NF-κB/Nrf2 and TGF-β/PKC/TRPV1 signaling pathways.
Topics: Animals; Caffeine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperglycemia; Hypoglycem | 2022 |
Modulatory effects of vitamin B3 and its derivative on the levels of apoptotic and vascular regulators and cytoskeletal proteins in diabetic rat brain as signs of neuroprotection.
Topics: Animals; Brain; Cytoskeletal Proteins; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hyp | 2022 |
Dietary supplementation with nicotinamide riboside improves fetal growth under hypoglycemia.
Topics: Animals; Dietary Supplements; Female; Fetal Development; Humans; Hyperglycemia; Hypoglycemia; Hypogl | 2023 |
Biochemical Evidence Indicates the Preventive Effect of Resveratrol and Nicotinamide in the Treatment of STZ-induced Diabetic Cataract.
Topics: Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; | 2021 |
Antihyperalgesic activity of a mexicanolide isolated from Swietenia humilis extract in nicotinamide-streptozotocin hyperglycemic mice.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Hyperalgesia; Hyperglycemia; Hypoglycemic Agen | 2017 |
Inhibitory effect of vitamin B
Topics: Glucose; Glycation End Products, Advanced; Glycosylation; Humans; Hyperglycemia; Molecular Docking S | 2017 |
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cytokines; Diabetes Mel | 2017 |
Peppermint essential oil alleviates hyperglycemia caused by streptozotocin- nicotinamide-induced type 2 diabetes in rats.
Topics: Administration, Oral; Animals; Antioxidants; Diabetes Mellitus, Type 2; Free Radical Scavengers; Gly | 2017 |
Glycaemic adverse drug reactions from anti-neoplastics used in treating pancreatic cancer.
Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents; Blood Glucose; China; Deoxycytidine; | 2017 |
Eugenosedin-A improves glucose metabolism and inhibits MAPKs expression in streptozotocin/nicotinamide-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Gene Expression Regulation; | 2018 |
Betanin exhibits significant potential as an antihyperglycemic and attenuating the glycoprotein components in streptozotocin-nicotinamide-induced experimental rats.
Topics: Animals; Betacyanins; Biomarkers; Body Weight; Combined Modality Therapy; Diabetes Mellitus, Experim | 2018 |
Therapeutic effect of vitamin B
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 2018 |
Moringa concanensis Nimmo extracts ameliorates hyperglycemia-mediated oxidative stress and upregulates PPARγ and GLUT4 gene expression in liver and pancreas of streptozotocin-nicotinamide induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Gene Expression; Glucose Transporter Type 4; Hyperglycemia | 2019 |
Effects of pomegranate aril juice and its punicalagin on some key regulators of insulin resistance and oxidative liver injury in streptozotocin-nicotinamide type 2 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Hydrolyzable Tannins; | 2019 |
Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats.
Topics: Administration, Intravenous; Animals; Brain; Disease Models, Animal; Doublecortin Protein; Humans; H | 2019 |
[Protective effect of cytoflavin and its components in mice with acute alloxan intoxication].
Topics: Acute Disease; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Drug Combinations; Female | 2013 |
Ameliorative effect of naringenin on hyperglycemia-mediated inflammation in hepatic and pancreatic tissues of Wistar rats with streptozotocin- nicotinamide-induced experimental diabetes mellitus.
Topics: Animals; Antioxidants; C-Reactive Protein; Cytokines; Diabetes Mellitus, Experimental; Flavanones; H | 2013 |
Diabetic characteristics and alveolar bone loss in streptozotocin- and streptozotocin-nicotinamide-treated rats with periodontitis.
Topics: Alveolar Bone Loss; Animals; Blood Glucose; Body Weight; Bone Matrix; Bone Resorption; Diabetes Mell | 2014 |
Antidiabetic activity of benzopyrone analogues in nicotinamide-streptozotocin induced type 2 diabetes in rats.
Topics: Animals; Biomarkers; Blood Glucose; Coumarins; Creatinine; Diabetes Mellitus, Experimental; Diabetes | 2014 |
Increased SIRT3 Expression and Antioxidant Defense under Hyperglycemic Conditions in HepG2 Cells.
Topics: Antioxidants; Cell Survival; Cyclic AMP Response Element-Binding Protein; DNA, Mitochondrial; Gene E | 2015 |
Dietary resistant maltodextrin ameliorates testicular function and spermatogenesis in streptozotocin-nicotinamide-induced diabetic rats.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Apoptosis; Diabetes Mell | 2016 |
Ethyl acetate fraction of Cissus quadrangularis stem ameliorates hyperglycaemia-mediated oxidative stress and suppresses inflammatory response in nicotinamide/streptozotocin induced type 2 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cissus; Cytokines; Diabetes Mellitus, Experimental; Glycated H | 2015 |
Streptozotocin-Induced Diabetic Models in Mice and Rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet | 2015 |
Extract of Woodfordia fruticosa flowers ameliorates hyperglycemia, oxidative stress and improves β-cell function in streptozotocin-nicotinamide induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Flowers; Glucose Transporter Type 2; Glucose Transporter T | 2015 |
Rhinacanthin C ameliorates hyperglycaemia, hyperlipidemia and pancreatic destruction in streptozotocin-nicotinamide induced adult male diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, D | 2016 |
Insulin-Producing Cells Differentiated from Human Bone Marrow Mesenchymal Stem Cells In Vitro Ameliorate Streptozotocin-Induced Diabetic Hyperglycemia.
Topics: Adipocytes; Animals; Apoptosis; Bone Marrow Cells; Calcium Channels; Cell Differentiation; Chondrocy | 2016 |
Time Course of Molecular and Metabolic Events in the Development of Insulin Resistance in Fructose-Fed Rats.
Topics: Animals; Carbohydrate Metabolism; Fructose; Hyperglycemia; Insulin Resistance; Lipid Metabolism; Liv | 2016 |
Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents | 2008 |
Effect of guava (Psidium guajava Linn.) leaf soluble solids on glucose metabolism in type 2 diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Toleranc | 2008 |
Effects of the combination of dipeptidyl peptidase-IV inhibitor ASP8497 and antidiabetic drugs in streptozotocin-nicotinamide-induced mildly diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Pepti | 2009 |
Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats.
Topics: Animals; Antioxidants; Cytokines; Diabetes Mellitus, Experimental; Gliclazide; Hepatocytes; Hypergly | 2010 |
Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Fasting; Hyperglyc | 2010 |
Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Free Radical Scavengers; Glucose Tolerance | 2010 |
Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice.
Topics: Animals; Atrophy; Blood Glucose; Body Weight; Cell Proliferation; Cytokines; Diabetes Mellitus, Expe | 2010 |
SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence.
Topics: Animals; Cells, Cultured; Cellular Senescence; Enzyme Inhibitors; Gene Silencing; Hyperglycemia; Mal | 2012 |
The methanolic fraction of Centratherum anthelminticum seed downregulates pro-inflammatory cytokines, oxidative stress, and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats.
Topics: Animals; Antioxidants; Asteraceae; Cells, Cultured; Cytokines; Diabetes Mellitus, Type 2; Hyperglyce | 2012 |
Loss of beta-cell mass leads to a reduction of pulse mass with normal periodicity, regularity and entrainment of pulsatile insulin secretion in Göttingen minipigs.
Topics: Animals; Cell Death; Drug Combinations; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerh | 2003 |
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen | 2004 |
Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Blood Glucose; Ceruloplasmin; Curcumi | 2006 |
Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitu | 2007 |
Participation of adrenal medulla in 6-amino-nicotinamide-induced hyperglycaemia in the rat.
Topics: 6-Aminonicotinamide; Adrenal Medulla; Animals; Blood Glucose; Female; Guanethidine; Hyperglycemia; I | 1980 |
Accidental ingestion of Vacor rodenticide: the symptoms and sequelae in a 25-month-old child.
Topics: Accidents, Home; Child, Preschool; Chronic Disease; Humans; Hyperglycemia; Hypoglycemia; Male; Neuro | 1980 |
The amelioration of hyperglycemia in streptozotocin-induced diabetic rats after the intraportal transplantation of an insufficient number of islets by nicotinamide treatment.
Topics: Animals; Diabetes Mellitus, Experimental; Hyperglycemia; Insulin; Islets of Langerhans Transplantati | 1995 |
Protection of intrahepatic islet grafts from hyperglycemic toxicity by nicotinamide treatment.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hyperglycemia; Insulin; Islets of Langerhan | 1995 |
Protective effects of nicotinamide on renal subcapsular islet isografts with a marginal mass from sustained hyperglycemia in the streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Cell Degranulation; Diabetes Mellitus, Experimental; Hyperglycemia; Islets o | 1995 |
Poor capacity for proliferation of pancreatic beta-cells in Otsuka-Long-Evans-Tokushima Fatty rat: a model of spontaneous NIDDM.
Topics: Animals; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fe | 1996 |
Attenuation by nicotinamide of the streptozocin induced early hyperglycaemia in fasting rats.
Topics: Animals; Antibiotics, Antineoplastic; Dose-Response Relationship, Drug; Fasting; Hyperglycemia; Male | 1996 |
Effect of partial pancreatectomy on beta-cell mass in the remnant pancreas of Wistar fatty rats.
Topics: Animals; Blood Glucose; Cell Division; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, | 1998 |
Acceleration of the development of diabetes in obese diabetic (db/db) mice by nicotinamide: a comparison with its antidiabetic effects in non-obese diabetic mice.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Progression; Female; Glycosuria; Hyperglycemia; Insulin; | 2000 |
Delayed treatment with nicotinamide (vitamin B3) reduces the infarct volume following focal cerebral ischemia in spontaneously hypertensive rats, diabetic and non-diabetic Fischer 344 rats.
Topics: Animals; Blood Gas Analysis; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Diabe | 2002 |
Renal transport of organic acids and bases in genetically obese mice.
Topics: Acetates; Aminohippuric Acids; Animals; Body Weight; Disease Models, Animal; Female; Hyperglycemia; | 1975 |
Centrally mediated hyperglycemia by 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Adrenalectomy; Animals; Blood Glucose; Brain; Glycogen; Hyperglycemia; Hypoglyc | 1978 |
Modulation of streptozotocin-induced insulitis and hyperglycaemia in the mouse.
Topics: Animals; Diabetes Mellitus, Experimental; Hyperglycemia; Inflammation; Islets of Langerhans; Male; M | 1985 |
[On the mechanism of 6-aminonicotinamide hyperglycemia].
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood; Corticosterone; Epinephrine; Ergotamine; Glucose; Gly | 1966 |
Diabetogenic action of streptozotocin: relationship of dose to metabolic response.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Glucosamine; Glucose Tolerance Te | 1969 |
[Differentiation of functional disturbances of the central nervous system evoked by 6-aminonicotinamide, an antimetabolite of nicotinamide].
Topics: Animals; Antimetabolites; Blood Glucose; Body Temperature; Body Weight; Extrapyramidal Tracts; Femal | 1970 |
[Hyperglycemic effect of nicotinamide].
Topics: Animals; Epinephrine; Hyperglycemia; Hypoglycemia; Insulin; Niacinamide; Rabbits | 1970 |
[Study of a mechanism of hyperglycemic action of nicotinamide].
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Glucose; Catecholamines; Diet; Glycogen; Hydrocortison | 1970 |
Effect of 6-amino-nicotinamide on the tolerance of mice to hypoxic hypoxia.
Topics: Amines; Animals; Blood Glucose; Body Temperature; Brain; Glucose; Hyperglycemia; Hypoxia; Male; Mice | 1974 |
Studies on the ability of compounds to block the diabetogenic activity of streptozotocin.
Topics: Amino Acids; Animals; Diabetes Mellitus; Diaphragm; Diazoxide; Epinephrine; Ethanol; Glucosamine; Gl | 1969 |
Effects of streptozotocin on carbohydrate and lipid metabolism in the rat.
Topics: Acetoacetates; Animals; Antibiotics, Antineoplastic; Blood Glucose; Carbamates; Diabetes Mellitus; D | 1971 |
Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide-adenine dinucleotide.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Female; Glucose; Hyperglycemia; Insulin; Insulin Sec | 1974 |