gatifloxacin has been researched along with Hyperglycemia in 29 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
Hyperglycemia: Abnormally high BLOOD GLUCOSE level.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this report was to describe a new case of gatifloxacin-associated hyperglycemia in an elderly patient and to provide a summary of case reports." | 8.83 | Gatifloxacin-induced hyperglycemia: a case report and summary of the current literature. ( Lee, AJ; Yip, C, 2006) |
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 7.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| "To compare rates of hypoglycemia and hyperglycemia among elderly hospitalized patients with normal blood glucose concentrations at baseline who were receiving either gatifloxacin or levofloxacin, and to determine if appropriateness of their doses, according to their package inserts, was associated with hypoglycemia or hyperglycemia." | 7.74 | Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients. ( Graves, J; Lodise, T; Lomaestro, B; Miller, C; Mohr, JF; Smith, RP, 2007) |
| "Gatifloxacin, until recently one of the most commonly prescribed antibiotics, has been shown to produce hypoglycemia." | 7.74 | Gatifloxacin produces both hypoglycemia and hyperglycemia: a retrospective study. ( Brown, R; Haerian, H; McHugh, P; Solomon, SS; Somes, G, 2008) |
| "This retrospective, nested case-controlled study found that the risk of hyperglycemia increased in diabetic patients who received concomitant steroids or higher gatifloxacin doses than recommended by the manufacturer's prescribing information." | 7.74 | Risk factors for hyperglycemia in hospitalized adults receiving gatifloxacin: a retrospective, nested case-controlled analysis. ( Lodise, TP; Mohr, JF; Ostrosky-Zeichner, L; Peymann, PJ; Troxell, E, 2008) |
| "Our goal was to report a new case of gatifloxacin-related hyperglycemia in a nondiabetic patient with acute renal dysfunction." | 7.73 | Hyperglycemia and gatifloxacin: a case report and summary of current literature. ( Beste, LA; Mersfelder, TL, 2005) |
| "To report a case of possible gatifloxacin-induced hyperglycemia in a nondiabetic middle-aged woman." | 7.72 | Possible gatifloxacin-induced hyperglycemia. ( Donaldson, AR; Finch, CK; Vandiver, JR, 2004) |
| "Gatifloxacin was stopped." | 5.34 | Advancing age and renal impairment as important predisposing factors of gatifloxacin-induced hyperglycemia in non-diabetes patients. ( Jongjaroenprasert, W; Ovartlarnporn, M, 2007) |
| "The purpose of this report was to describe a new case of gatifloxacin-associated hyperglycemia in an elderly patient and to provide a summary of case reports." | 4.83 | Gatifloxacin-induced hyperglycemia: a case report and summary of the current literature. ( Lee, AJ; Yip, C, 2006) |
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 3.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| "To compare rates of hypoglycemia and hyperglycemia among elderly hospitalized patients with normal blood glucose concentrations at baseline who were receiving either gatifloxacin or levofloxacin, and to determine if appropriateness of their doses, according to their package inserts, was associated with hypoglycemia or hyperglycemia." | 3.74 | Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients. ( Graves, J; Lodise, T; Lomaestro, B; Miller, C; Mohr, JF; Smith, RP, 2007) |
| "To assess the prevalence of dysglycemia (hypoglycemia or hyperglycemia) associated with oral levofloxacin and gatifloxacin therapy in an outpatient setting, and to determine the characteristics of patients who developed dysglycemia while receiving either fluoroquinolone." | 3.74 | Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting. ( LaPlante, KL; Mersfelder, TL; Quilliam, BJ; Ward, KE, 2008) |
| "Gatifloxacin, until recently one of the most commonly prescribed antibiotics, has been shown to produce hypoglycemia." | 3.74 | Gatifloxacin produces both hypoglycemia and hyperglycemia: a retrospective study. ( Brown, R; Haerian, H; McHugh, P; Solomon, SS; Somes, G, 2008) |
| "A retrospective cohort study of hospitalized adult (> or =18 years) patients admitted with Community Acquired Pneumonia (CAP) or Acute Exacerbation of Chronic Bronchitis (AECB) in a US tertiary care hospital between 7/1/01 and 12/31/04 treated with gatifloxacin or ceftriaxone during hospital admission." | 3.74 | An evaluation of the effects of gatifloxacin on glucose homeostasis. ( Hatton, RC; Onyenwenyi, AJ; Winterstein, AG, 2008) |
| "This retrospective, nested case-controlled study found that the risk of hyperglycemia increased in diabetic patients who received concomitant steroids or higher gatifloxacin doses than recommended by the manufacturer's prescribing information." | 3.74 | Risk factors for hyperglycemia in hospitalized adults receiving gatifloxacin: a retrospective, nested case-controlled analysis. ( Lodise, TP; Mohr, JF; Ostrosky-Zeichner, L; Peymann, PJ; Troxell, E, 2008) |
| "Our goal was to report a new case of gatifloxacin-related hyperglycemia in a nondiabetic patient with acute renal dysfunction." | 3.73 | Hyperglycemia and gatifloxacin: a case report and summary of current literature. ( Beste, LA; Mersfelder, TL, 2005) |
| " In the first, case patients were persons treated in the hospital for hypoglycemia after outpatient treatment with a macrolide, a second-generation cephalosporin, or a respiratory fluoroquinolone (gatifloxacin, levofloxacin, moxifloxacin, or ciprofloxacin)." | 3.73 | Outpatient gatifloxacin therapy and dysglycemia in older adults. ( Dresser, L; Juurlink, DN; Kopp, A; Low, DE; Mamdani, MM; Park-Wyllie, LY; Shah, BR; Stukel, TA; Stumpo, C, 2006) |
| "Gatifloxacin, a commonly prescribed antimicrobial can produce profound hypoglycemia and disturbances in glucose homeostasis especially in diabetes patients on sulphonylureas." | 3.73 | Gatifloxacin induced abnormalities in glucose homeostasis in a patient on glimepiride. ( Kesavadev, J; Rasheed, SA, 2006) |
| "To report a case of possible gatifloxacin-induced hyperglycemia in a nondiabetic middle-aged woman." | 3.72 | Possible gatifloxacin-induced hyperglycemia. ( Donaldson, AR; Finch, CK; Vandiver, JR, 2004) |
| "Gatifloxacin has been reported to cause dysglycaemia, especially in the elderly and in diabetics." | 1.35 | Gatifloxacin-induced severe hyperglycaemia and ketoacidosis in a non-diabetic renal transplant recipient. ( Agarwal, SK; Gupta, A; Khaira, A; Tandon, N, 2009) |
| "Gatifloxacin was stopped." | 1.34 | Advancing age and renal impairment as important predisposing factors of gatifloxacin-induced hyperglycemia in non-diabetes patients. ( Jongjaroenprasert, W; Ovartlarnporn, M, 2007) |
| "Gatifloxacin was found to be the probable cause in the majority of cases." | 1.33 | Gatifloxacin-induced dysglycemia. ( Zvonar, R, 2006) |
| "First, a previously derived population pharmacokinetic model, with patient demographics, was used to estimate gatifloxacin AUC0-24 following a dosage regimen of 400 mg/24 h in 10 index patients with severe hyperglycaemia." | 1.32 | Gatifloxacin and the elderly: pharmacokinetic-pharmacodynamic rationale for a potential age-related dose reduction. ( Ambrose, PG; Bhavnani, SM; Cirincione, BB; Grasela, TH; Piedmonte, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 26 (89.66) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khaira, A | 1 |
| Gupta, A | 1 |
| Tandon, N | 1 |
| Agarwal, SK | 1 |
| Ishiwata, Y | 1 |
| Yasuhara, M | 1 |
| Vinh, H | 1 |
| Anh, VT | 1 |
| Anh, ND | 1 |
| Campbell, JI | 1 |
| Hoang, NV | 1 |
| Nga, TV | 1 |
| Nhu, NT | 1 |
| Minh, PV | 1 |
| Thuy, CT | 1 |
| Duy, PT | 1 |
| Phuong, le T | 1 |
| Loan, HT | 1 |
| Chinh, MT | 1 |
| Thao, NT | 1 |
| Tham, NT | 1 |
| Mong, BL | 1 |
| Bay, PV | 1 |
| Day, JN | 1 |
| Dolecek, C | 1 |
| Lan, NP | 1 |
| Diep, TS | 1 |
| Farrar, JJ | 1 |
| Chau, NV | 1 |
| Wolbers, M | 1 |
| Baker, S | 1 |
| Yu, Y | 1 |
| Wang, X | 1 |
| Liu, C | 1 |
| Yao, D | 1 |
| Hu, M | 1 |
| Li, J | 1 |
| Hu, N | 1 |
| Liu, L | 1 |
| Liu, X | 1 |
| Ambrose, PG | 1 |
| Bhavnani, SM | 1 |
| Cirincione, BB | 1 |
| Piedmonte, M | 1 |
| Grasela, TH | 1 |
| Donaldson, AR | 1 |
| Vandiver, JR | 1 |
| Finch, CK | 1 |
| Happe, MR | 1 |
| Mulhall, BP | 1 |
| Maydonovitch, CL | 1 |
| Holtzmuller, KC | 1 |
| Khovidhunkit, W | 1 |
| Sunthornyothin, S | 1 |
| Mohr, JF | 3 |
| McKinnon, PS | 1 |
| Peymann, PJ | 2 |
| Kenton, I | 1 |
| Septimus, E | 1 |
| Okhuysen, PC | 1 |
| Bushardt, RL | 1 |
| Bobba, RK | 1 |
| Arsura, EL | 1 |
| Tailor, SA | 1 |
| Simor, AE | 1 |
| Cornish, W | 1 |
| Phillips, EJ | 1 |
| Knowles, S | 1 |
| Rachlis, A | 1 |
| Beste, LA | 1 |
| Mersfelder, TL | 2 |
| Park-Wyllie, LY | 2 |
| Juurlink, DN | 2 |
| Kopp, A | 1 |
| Shah, BR | 1 |
| Stukel, TA | 1 |
| Stumpo, C | 1 |
| Dresser, L | 1 |
| Low, DE | 1 |
| Mamdani, MM | 1 |
| Gurwitz, JH | 1 |
| Kendall, C | 1 |
| Wooltorton, E | 1 |
| Ittner, KP | 1 |
| Yadav, V | 1 |
| Deopujari, K | 1 |
| Zvonar, R | 1 |
| Yip, C | 1 |
| Lee, AJ | 1 |
| Catero, M | 1 |
| Kesavadev, J | 1 |
| Rasheed, SA | 1 |
| Ovartlarnporn, M | 1 |
| Jongjaroenprasert, W | 1 |
| Lodise, T | 1 |
| Graves, J | 1 |
| Miller, C | 1 |
| Lomaestro, B | 1 |
| Smith, RP | 1 |
| Kapral, MK | 1 |
| LaPlante, KL | 1 |
| Ward, KE | 1 |
| Quilliam, BJ | 1 |
| Haerian, H | 1 |
| McHugh, P | 1 |
| Brown, R | 1 |
| Somes, G | 1 |
| Solomon, SS | 1 |
| Onyenwenyi, AJ | 1 |
| Winterstein, AG | 1 |
| Hatton, RC | 1 |
| Troxell, E | 1 |
| Lodise, TP | 1 |
| Ostrosky-Zeichner, L | 1 |
2 reviews available for gatifloxacin and Hyperglycemia
| Article | Year |
|---|---|
Gatifloxacin-induced hyperglycemia: a case report and summary of the current literature.
Topics: Age Factors; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Fluoroquinolones; Gatifloxacin | 2006 |
Dysglycemia and fluoroquinolones: are you putting patients at risk?
Topics: Adolescent; Adult; Aza Compounds; Bacterial Infections; Blood Glucose; Ciprofloxacin; Dose-Response | 2007 |
1 trial available for gatifloxacin and Hyperglycemia
| Article | Year |
|---|---|
A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children.
Topics: Anti-Bacterial Agents; Child, Preschool; Ciprofloxacin; Dysentery, Bacillary; Feces; Female; Fluoroq | 2011 |
26 other studies available for gatifloxacin and Hyperglycemia
| Article | Year |
|---|---|
Gatifloxacin-induced severe hyperglycaemia and ketoacidosis in a non-diabetic renal transplant recipient.
Topics: Anti-Infective Agents; Diabetic Ketoacidosis; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; | 2009 |
Gatifloxacin-induced histamine release and hyperglycemia in rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Blood Glucose; Diabetes Mellitus, Experimental | 2010 |
Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats.
Topics: Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Fluoroquinolones; Gatifloxacin; | 2013 |
Gatifloxacin and the elderly: pharmacokinetic-pharmacodynamic rationale for a potential age-related dose reduction.
Topics: Aged; Aged, 80 and over; Aging; Algorithms; Anti-Bacterial Agents; Area Under Curve; Bayes Theorem; | 2003 |
Possible gatifloxacin-induced hyperglycemia.
Topics: Anti-Infective Agents, Urinary; Female; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Middl | 2004 |
Gatifloxacin-induced hyperglycemia.
Topics: Anti-Infective Agents; Cholangitis, Sclerosing; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemi | 2004 |
Hypoglycemia, hyperglycemia, and gatifloxacin.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Diabetes Mellitus, Type 2; Female; Fluoroquinolones; | 2004 |
A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Ceftriaxone; Ciprofloxacin; Fe | 2005 |
Fluctuating blood glucose levels in an elderly diabetic patient.
Topics: Aged; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Interactions; Fluoroq | 2006 |
Hyperglycemia in an elderly diabetic patient: drug-drug or drug-disease interaction?
Topics: Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug | 2006 |
Glucose homeostasis abnormalities and gatifloxacin.
Topics: Aza Compounds; Fluoroquinolones; Gatifloxacin; Glucose; Homeostasis; Humans; Hyperglycemia; Hypoglyc | 2006 |
Hyperglycemia and gatifloxacin: a case report and summary of current literature.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Blood Glucose; Coronary Artery Bypass; Fluoroquino | 2005 |
Outpatient gatifloxacin therapy and dysglycemia in older adults.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Case-Control Studies; Cephalosporin | 2006 |
Serious adverse drug effects--seeing the trees through the forest.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglycemia | 2006 |
People with diabetes should avoid antibiotic gatifloxacin.
Topics: Bacterial Infections; Case-Control Studies; Contraindications; Diabetes Mellitus; Fluoroquinolones; | 2006 |
Gatifloxacin and dysglycemia in older adults.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglycemia | 2006 |
Gatifloxacin and dysglycemia in older adults.
Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglycemia; Mortalit | 2006 |
Gatifloxacin-induced dysglycemia.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Female; Fluoroquinolones; Gatifloxacin; Humans; Hype | 2006 |
Gatifloxacin induced abnormalities in glucose homeostasis in a patient on glimepiride.
Topics: Anti-Infective Agents; Blood Glucose; Diabetes Mellitus; Female; Fluoroquinolones; Gatifloxacin; Hom | 2006 |
Advancing age and renal impairment as important predisposing factors of gatifloxacin-induced hyperglycemia in non-diabetes patients.
Topics: Age Factors; Aged; Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Kid | 2007 |
Effects of gatifloxacin and levofloxacin on rates of hypoglycemia and hyperglycemia among elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cohort Studies; Dose-Response Relationship, Drug; Fe | 2007 |
The effect of publication on Internet-based solicitation of personal-injury litigants.
Topics: Advertising; Aged; Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hyp | 2007 |
Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Creatinin | 2008 |
Gatifloxacin produces both hypoglycemia and hyperglycemia: a retrospective study.
Topics: Aged; Anti-Bacterial Agents; Female; Fluoroquinolones; Gatifloxacin; Humans; Hyperglycemia; Hypoglyc | 2008 |
An evaluation of the effects of gatifloxacin on glucose homeostasis.
Topics: Adult; Aged; Anti-Bacterial Agents; Blood Glucose; Bronchitis; Ceftriaxone; Cohort Studies; Communit | 2008 |
Risk factors for hyperglycemia in hospitalized adults receiving gatifloxacin: a retrospective, nested case-controlled analysis.
Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Case-Control Studies; Diabetes Mellitus; Dose- | 2008 |