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palmitic acid and Hyperglycemia

palmitic acid has been researched along with Hyperglycemia in 29 studies

Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"Curcumin improves muscular insulin resistance by increasing oxidation of fatty acid and glucose, which is, at least in part, mediated through LKB1-AMPK pathway."7.77Curcumin improves insulin resistance in skeletal muscle of rats. ( Kong, T; Li, R; Li, Y; Liu, LY; Na, LX; Sun, CH; Zhang, YL, 2011)
" We then describe glial transcriptome alterations in response to systemic circulating factors that are upregulated in patients with diabetes and diabetes-related comorbidities; namely glucose in hyperglycemia, angiotensin II in hypertension, and the free fatty acid palmitic acid in hyperlipidemia."5.41Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis. ( Capozzi, ME; Padovani-Claudio, DA; Penn, JS; Ramos, CJ, 2023)
"Curcumin improves muscular insulin resistance by increasing oxidation of fatty acid and glucose, which is, at least in part, mediated through LKB1-AMPK pathway."3.77Curcumin improves insulin resistance in skeletal muscle of rats. ( Kong, T; Li, R; Li, Y; Liu, LY; Na, LX; Sun, CH; Zhang, YL, 2011)
"Palmitic acid is a saturated fat found in foods that lead to obesity, cardiovascular disease, and Type II diabetes."2.47The twists and turns of sphingolipid pathway in glucose regulation. ( Deevska, GM; Nikolova-Karakashian, MN, 2011)
"Although hyperglycemia is the main instigator in the development of diabetic retinopathy, dyslipidemia is also considered to play an important role."1.42Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy. ( Kowluru, A; Kowluru, RA; Kumar, B, 2015)
"The prognosis for women with breast cancer is adversely affected by the comorbidities of obesity and diabetes mellitus (DM), which are conditions associated with elevated levels of circulating fatty acids, hyperglycaemia and hyperinsulinaemia."1.36Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase. ( Biernacka, KM; Foulstone, EJ; Holly, JM; Jarrett, C; Morgan, A; Morrison, AA; Perks, CM; Shield, JP; Winters, ZE; Zeng, L, 2010)
"Diazoxide (DZ) was used to decrease serum insulin and generate hyperglycemia."1.35Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid. ( Abrahani, A; Deppe, S; Ghosh, S; Kewalramani, G; Kim, MS; Puthanveetil, P; Rodrigues, B; Wang, F, 2009)
"Hyperglycemia has been postulated to increase diacylglycerol (DAG) level through de novo synthesis pathway and subsequently activate protein kinase C (PKC) in vascular cells, possibly leading to vascular dysfunction associated with diabetes."1.30Effect of eicosapentaenoic acid on glucose-induced diacylglycerol synthesis in cultured bovine aortic endothelial cells. ( Inoguchi, T; Kuroki, T; Nawata, H; Umeda, F, 1998)
"To examine whether hyperglycemia is an independent regulator of adipose tissue lipolysis, we measured palmitate flux ([3H]palmitate) on two occasions in eight volunteers with insulin-dependent diabetes."1.29Lack of effect of hyperglycemia on lipolysis in humans. ( Cersosimo, E; Coppack, S; Jensen, M, 1993)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (17.24)18.2507
2000's6 (20.69)29.6817
2010's16 (55.17)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Tiwary, S1
Nandwani, A1
Khan, R1
Datta, M1
Padovani-Claudio, DA1
Ramos, CJ1
Capozzi, ME1
Penn, JS1
Rumora, AE1
Lentz, SI1
Hinder, LM1
Jackson, SW1
Valesano, A1
Levinson, GE1
Feldman, EL1
Pflimlin, E1
Bielohuby, M1
Korn, M1
Breitschopf, K1
Löhn, M1
Wohlfart, P1
Konkar, A1
Podeschwa, M1
Bärenz, F1
Pfenninger, A1
Schwahn, U1
Opatz, T1
Reimann, M1
Petry, S1
Tennagels, N1
Mazibuko-Mbeje, SE1
Dludla, PV1
Roux, C1
Johnson, R1
Ghoor, S1
Joubert, E1
Louw, J1
Opoku, AR1
Muller, CJF1
Zhou, L1
Cai, X1
Han, X1
Ji, L1
Kumar, B1
Kowluru, A1
Kowluru, RA1
Titov, VN1
Shoibonov, BB1
Xiong, X1
Sun, X1
Wang, Q1
Qian, X1
Zhang, Y1
Pan, X1
Dong, XC1
Du, K1
Murakami, S1
Sun, Y1
Kilpatrick, CL1
Luscher, B1
Wang, F1
Kim, MS1
Puthanveetil, P1
Kewalramani, G1
Deppe, S1
Ghosh, S2
Abrahani, A2
Rodrigues, B2
Gao, D1
Bailey, CJ1
Griffiths, HR1
Han, J1
Liu, YQ1
Na, LX1
Zhang, YL1
Li, Y1
Liu, LY1
Li, R1
Kong, T1
Sun, CH1
Zeng, L1
Biernacka, KM1
Holly, JM1
Jarrett, C1
Morrison, AA1
Morgan, A1
Winters, ZE1
Foulstone, EJ1
Shield, JP1
Perks, CM1
Deevska, GM1
Nikolova-Karakashian, MN1
Saitoh, Y1
Hongwei, W1
Ueno, H1
Mizuta, M1
Nakazato, M1
Padilla, A1
Descorbeth, M1
Almeyda, AL1
Payne, K1
De Leon, M1
Billestrup, N1
Bernardi, S1
Zauli, G1
Tikellis, C1
Candido, R1
Fabris, B1
Secchiero, P1
Cooper, ME1
Thomas, MC1
An, D1
Pulinilkunnil, T1
Qi, D1
Lau, HC1
Innis, SM1
Mohanty, S1
Spinas, GA1
Maedler, K1
Zuellig, RA1
Lehmann, R1
Donath, MY1
Trüb, T1
Niessen, M1
Bellin, C1
de Wiza, DH1
Wiernsperger, NF1
Rösen, P1
Morris, RT1
Laye, MJ1
Lees, SJ1
Rector, RS1
Thyfault, JP1
Booth, FW1
Pouliot, JF1
Béliveau, R1
Cersosimo, E1
Coppack, S1
Jensen, M1
Kuroki, T1
Inoguchi, T1
Umeda, F1
Nawata, H1
Ouchi, K1
Sakai, K1
Sato, R1
Mikuni, J1
Matsuno, S1
Caruso, M1
Divertie, GD1
Jensen, MD1
Miles, JM1

Reviews

2 reviews available for palmitic acid and Hyperglycemia

ArticleYear
Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis.
    Progress in retinal and eye research, 2023, Volume: 94

    Topics: Angiotensin II; Diabetes Mellitus; Diabetic Retinopathy; Glucose; Humans; Hyperglycemia; Hypertensio

2023
The twists and turns of sphingolipid pathway in glucose regulation.
    Biochimie, 2011, Volume: 93, Issue:1

    Topics: Animals; Ceramides; Diabetes Mellitus, Type 2; Dietary Fats; Glucose; Humans; Hyperglycemia; Insulin

2011

Other Studies

27 other studies available for palmitic acid and Hyperglycemia

ArticleYear
GRP75 mediates endoplasmic reticulum-mitochondria coupling during palmitate-induced pancreatic β-cell apoptosis.
    The Journal of biological chemistry, 2021, Volume: 297, Issue:6

    Topics: Animals; Apoptosis; Calcium; Cell Line; Cell Line, Tumor; Endoplasmic Reticulum; Glucose Tolerance T

2021
Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:1

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Dyslipidemias; Energy Metabolism; Ganglia

2018
Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice.
    Cell metabolism, 2018, 08-07, Volume: 28, Issue:2

    Topics: Animals; Diet, Fat-Restricted; Diet, High-Fat; Glucagon-Like Peptide 1; Glucose; HEK293 Cells; Human

2018
Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways.
    International journal of molecular sciences, 2019, Feb-01, Volume: 20, Issue:3

    Topics: 3T3 Cells; AMP-Activated Protein Kinases; Animals; Aspalathus; Carnitine O-Palmitoyltransferase; Cel

2019
P38 plays an important role in glucolipotoxicity-induced apoptosis in INS-1 cells.
    Journal of diabetes research, 2014, Volume: 2014

    Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Enzyme Activation; Fatty Acids, Nonesterified; Hype

2014
Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy.
    Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:5

    Topics: Animals; Cytochromes b; Diabetic Retinopathy; DNA Damage; DNA, Mitochondrial; Drug Synergism; Endoth

2015
[THE UNESTERIFIED FATTY ACIDS IN BLOOD PLASMA AND INTERCELLULAR MEDIUM: EFFECT OF INSULIN AND ALBUMIN (THE LECTURE)].
    Klinicheskaia laboratornaia diagnostika, 2016, Volume: 61, Issue:2

    Topics: Adenosine Triphosphate; Adipose Tissue; Biological Transport; Fatty Acids, Nonesterified; Glucose; H

2016
SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis.
    The Journal of endocrinology, 2016, Volume: 231, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cellular Senescence; Diabetes Mellitus, Type 2; Fatty

2016
DHHC7 Palmitoylates Glucose Transporter 4 (Glut4) and Regulates Glut4 Membrane Translocation.
    The Journal of biological chemistry, 2017, 02-17, Volume: 292, Issue:7

    Topics: 3T3-L1 Cells; Acyltransferases; Adipocytes; Animals; Cell Membrane; Glucose Tolerance Test; Glucose

2017
Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:4

    Topics: Animals; Cattle; Cells, Cultured; Cytochalasin D; Cytoskeleton; Diazoxide; Disease Models, Animal; E

2009
Metabolic memory effect of the saturated fatty acid, palmitate, in monocytes.
    Biochemical and biophysical research communications, 2009, Oct-16, Volume: 388, Issue:2

    Topics: Biological Transport; Cell Line; Deoxyglucose; Glucose; Humans; Hyperglycemia; Insulin; Monocytes; P

2009
Reduction of islet pyruvate carboxylase activity might be related to the development of type 2 diabetes mellitus in Agouti-K mice.
    The Journal of endocrinology, 2010, Volume: 204, Issue:2

    Topics: Aging; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids; Glucose Tolerance Test; Hyper

2010
Curcumin improves insulin resistance in skeletal muscle of rats.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2011, Volume: 21, Issue:7

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Biological Transport; Cell Line; Curcumin; Deoxygluco

2011
Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase.
    Endocrine-related cancer, 2010, Volume: 17, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Death; Ceramides; Drug Evaluation, Preclini

2010
Candesartan attenuates fatty acid-induced oxidative stress and NAD(P)H oxidase activity in pancreatic beta-cells.
    Diabetes research and clinical practice, 2010, Volume: 90, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds;

2010
Hyperglycemia magnifies Schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity.
    Brain research, 2011, Jan-25, Volume: 1370

    Topics: Animals; Cell Death; Cells, Cultured; Diabetic Neuropathies; Endoplasmic Reticulum Chaperone BiP; Hu

2011
ID'ing a novel inhibitor of β-cell function, Id1.
    Diabetes, 2011, Volume: 60, Issue:10

    Topics: Animals; Cell Differentiation; Diabetes Mellitus; Dietary Fats; DNA Fingerprinting; Enzymes; Gene Ex

2011
TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation.
    Clinical science (London, England : 1979), 2012, Volume: 123, Issue:9

    Topics: Adiposity; Animals; Apoptosis; Calorimetry; Cytokines; Dietary Fats; Energy Intake; Glucose Toleranc

2012
Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death.
    Nutrition (Burbank, Los Angeles County, Calif.), 2004, Volume: 20, Issue:10

    Topics: Animals; Apoptosis; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Dietary Fats, Unsatura

2004
Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.
    Experimental cell research, 2005, Feb-01, Volume: 303, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cloning, Molecular; Glucose; Humans; Hyperg

2005
Generation of reactive oxygen species by endothelial and smooth muscle cells: influence of hyperglycemia and metformin.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2006, Volume: 38, Issue:11

    Topics: Animals; Antioxidants; Endothelium, Vascular; Glucose; Glycation End Products, Advanced; Hyperglycem

2006
Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:3

    Topics: Adipose Tissue; Aging; Aldehydes; Animals; Blood Glucose; Disease Models, Animal; Eating; Glutathion

2008
Palmitoylation of the glucose transporter in blood-brain barrier capillaries.
    Biochimica et biophysica acta, 1995, Mar-22, Volume: 1234, Issue:2

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Blood Glucose; Blood-Brain Barrier; Blotting, We

1995
Lack of effect of hyperglycemia on lipolysis in humans.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Techniqu

1993
Effect of eicosapentaenoic acid on glucose-induced diacylglycerol synthesis in cultured bovine aortic endothelial cells.
    Biochemical and biophysical research communications, 1998, Jun-18, Volume: 247, Issue:2

    Topics: Animals; Arachidonic Acid; Cattle; Cells, Cultured; Diabetic Angiopathies; Diglycerides; Eicosapenta

1998
Glucose overload and hepatic energy metabolism after resection of the cirrhotic liver in rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1991, Volume: 191, Issue:4

    Topics: Adenosine Triphosphate; Animals; Blood Glucose; Dietary Carbohydrates; Energy Intake; Energy Metabol

1991
Lack of effect of hyperglycemia on lipolysis in humans.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 1

    Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Gluc

1990