Page last updated: 2024-10-28

haloperidol and Hyperglycemia

haloperidol has been researched along with Hyperglycemia in 22 studies

Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Hyperglycemia: Abnormally high BLOOD GLUCOSE level.

Research Excerpts

ExcerptRelevanceReference
"Pharmacovigilance survey of spontaneously reported adverse events in risperidone-treated patients, with reports of haloperidol-associated hyperglycemia used as a control."7.72Risperidone-associated diabetes mellitus: a pharmacovigilance study. ( Cross, JT; Doraiswamy, PM; Koller, EA; Schneider, BS, 2003)
" The authors' goal was to assess the effects of clozapine, olanzapine, risperidone, and haloperidol on glucose and cholesterol levels in hospitalized patients with schizophrenia or schizoaffective disorder during a randomized double-blind 14-week trial."5.10Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychotics. ( Chakos, M; Citrome, L; Cooper, TB; Czobor, P; Lieberman, JA; Lindenmayer, JP; McEvoy, JP; Sheitman, B; Volavka, J, 2003)
"To report a case of fatal hyponatremia, marked hyperglycemia, and acute pancreatitis following simultaneous administration of paroxetine, fluphenazine, haloperidol and olanzapine."3.74Fatal hyponatremia and other metabolic disturbances associated with psychotropic drug polypharmacy. ( Alfirevic, Z; Degoricija, V; Vucicevic, Z; Vukicevic-Badouin, D, 2007)
"Pharmacovigilance survey of spontaneously reported adverse events in risperidone-treated patients, with reports of haloperidol-associated hyperglycemia used as a control."3.72Risperidone-associated diabetes mellitus: a pharmacovigilance study. ( Cross, JT; Doraiswamy, PM; Koller, EA; Schneider, BS, 2003)
"To examine quantitatively the association between glucose intolerance including diabetes mellitus and the use of the atypical antipsychotics clozapine, olanzapine or risperidone, and to identify possible risk factors for the development of glucose intolerance during treatment with these drugs."3.71Glucose intolerance with atypical antipsychotics. ( Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M, 2002)
" To investigate further the issue the effects of alloxan-induced hyperglycemia on the incidence and severity of haloperidol-induced perioral movements were studied in the rat."3.68Increased incidence of neuroleptic-induced perioral movements in the rat by hyperglycemia. ( Sandyk, R, 1990)
"We present a case of hemichorea/hemiballism, a rare complication of hyperglycemia."1.51[Hemichorea/hemiballism a rare complication of hyperglycemia]. ( Kataja Knight, A; Magnusson, P; Sjöholm, Å; Tidehag, L, 2019)
"Hemichorea is a disorder characterized by abnormal, continuous, nonrhythmic, jerky, and distal movement involving one side of the body."1.43Hemichorea with unilateral MRI striatal hyperintensity in a Saudi patient with diabetes. ( Al-Quliti, KW; Assaedi, ES, 2016)
"Three cases of hemichorea-hemiballismus (HC-HB) associated with nonketotic hyperglycemia were reported."1.35Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation. ( Deng, BQ; Wang, JH; Wang, ZK; Wu, T; Zhang, P; Zhang, YW, 2009)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's3 (13.64)18.2507
2000's10 (45.45)29.6817
2010's6 (27.27)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Ishikawa, S1
Yamamura, R1
Hashimoto, N1
Okubo, R1
Sawagashira, R1
Ito, YM1
Sato, N1
Kusumi, I1
Cho, HS1
Hong, CT1
Chan, L1
Tidehag, L1
Kataja Knight, A1
Magnusson, P1
Sjöholm, Å1
Al-Quliti, KW1
Assaedi, ES1
Lin, CJ1
Huang, P1
Wang, JH1
Wu, T1
Deng, BQ1
Zhang, YW1
Zhang, P1
Wang, ZK1
Rock, W1
Elias, M1
Lev, A1
Saliba, WR1
Rafai, MA1
Guynerane, M1
Boulaajaj, FZ1
Benchekroun, W1
El Moutawakkil, B1
Slassi, I1
Kim, YD1
Kim, JS1
Song, IU1
Lee, KS1
Kim, YI1
Hedenmalm, K1
Hägg, S1
Ståhl, M1
Mortimer, O1
Spigset, O1
Lindenmayer, JP1
Czobor, P1
Volavka, J1
Citrome, L1
Sheitman, B1
McEvoy, JP1
Cooper, TB1
Chakos, M1
Lieberman, JA1
Gupta, S1
Koller, EA1
Cross, JT1
Doraiswamy, PM1
Schneider, BS1
Guha, P1
Roy, K1
Sanyal, D1
Dasgupta, T1
Bhattacharya, K1
Wehrschuetz, M1
Simbrunner, J1
Enzinger, C1
Ebner, F1
Duncan, E1
Dunlop, BW1
Boshoven, W1
Woolson, SL1
Hamer, RM1
Phillips, LS1
Vucicevic, Z1
Degoricija, V1
Alfirevic, Z1
Vukicevic-Badouin, D1
Wannarka, GL1
Fletcher, HP1
Maickel, RP1
Iwata, A1
Koike, F1
Arasaki, K1
Tamaki, M1
Oerlemans, WG1
Moll, LC1
Brambilla, F1
Guastalla, A1
Guerrini, A1
Riggi, F1
Rovere, C1
Zanoboni, A1
Zanoboni-Muciaccia, W1
Sandyk, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Outcome Evaluation of Solutions for Wellness and Team Solutions Program in Patients With Severe Mental Illness[NCT00661869]295 participants (Actual)Interventional2006-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for haloperidol and Hyperglycemia

ArticleYear
Hemichorea after hyperglycemia correction: A case report and a short review of hyperglycemia-related hemichorea at the euglycemic state.
    Medicine, 2018, Volume: 97, Issue:10

    Topics: Aged; Anti-Dyskinesia Agents; Diagnosis, Differential; Dyskinesias; Haloperidol; Humans; Hyperglycem

2018
Safety in treating bipolar disorder.
    The Journal of family practice, 2003, Volume: Suppl

    Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Diabetes Melli

2003

Trials

2 trials available for haloperidol and Hyperglycemia

ArticleYear
Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychotics.
    The American journal of psychiatry, 2003, Volume: 160, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Cholesterol; Clozapine; Double-Bl

2003
Olanzapine-induced obesity and diabetes in Indian patients: a prospective trial comparing olanzapine with typical antipsychotics.
    Journal of the Indian Medical Association, 2005, Volume: 103, Issue:12

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; Body Weight; Diabetes

2005

Other Studies

18 other studies available for haloperidol and Hyperglycemia

ArticleYear
The type rather than the daily dose or number of antipsychotics affects the incidence of hyperglycemic progression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2022, 03-08, Volume: 113

    Topics: Adult; Antipsychotic Agents; Clozapine; Dibenzothiepins; Female; Haloperidol; Humans; Hyperglycemia;

2022
[Hemichorea/hemiballism a rare complication of hyperglycemia].
    Lakartidningen, 2019, Mar-26, Volume: 116

    Topics: Aged, 80 and over; Anti-Dyskinesia Agents; Basal Ganglia; Chorea; Dyskinesias; Female; Haloperidol;

2019
Hemichorea with unilateral MRI striatal hyperintensity in a Saudi patient with diabetes.
    Neurosciences (Riyadh, Saudi Arabia), 2016, Volume: 21, Issue:1

    Topics: Anti-Dyskinesia Agents; Chorea; Diabetes Complications; Diabetes Mellitus; Female; Haloperidol; Huma

2016
Delayed onset diabetic striatopathy: Hemichorea-hemiballism one month after a hyperglycemic episode.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:7

    Topics: Aged; Anti-Dyskinesia Agents; Anticonvulsants; Clonazepam; Diabetes Complications; Diagnosis, Differ

2017
Hemichorea-hemiballismus associated with nonketotic hyperglycemia: a possible role of inflammation.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Aged, 80 and over; Anti-Dyskinesia Agents; Autoimmune Diseases of the Nervous System; Chorea; Corpus

2009
Haloperidol-induced neuroleptic malignant syndrome complicated by hyperosmolar hyperglycemic state.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:8

    Topics: Adult; Antipsychotic Agents; Fatal Outcome; Haloperidol; Humans; Hyperglycemia; Male; Malignant Hype

2009
[Left hemichorea revealing non ketotic hyperglycemia].
    Revue neurologique, 2010, Volume: 166, Issue:10

    Topics: Brain; Caudate Nucleus; Chorea; Corpus Striatum; Dopamine Antagonists; Female; Functional Laterality

2010
Recurrence of hyperglycemic-induced chorea-ballismus after haloperidol withdrawal.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:4

    Topics: Aged, 80 and over; Antipsychotic Agents; Chorea; Haloperidol; Humans; Hyperglycemia; Male; Recurrenc

2011
Glucose intolerance with atypical antipsychotics.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlor

2002
Risperidone-associated diabetes mellitus: a pharmacovigilance study.
    Pharmacotherapy, 2003, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; An

2003
[Hemiballism-hemichorea syndrome].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2007, Volume: 179, Issue:1

    Topics: Anti-Dyskinesia Agents; Brain Diseases; Cerebrovascular Circulation; Chorea; Drug Therapy, Combinati

2007
Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration population.
    International clinical psychopharmacology, 2007, Volume: 22, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Chlorpromazine; Cohort Studies; Female; Fluphe

2007
Fatal hyponatremia and other metabolic disturbances associated with psychotropic drug polypharmacy.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:5

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain Edema; Fatal Outcome; Fluphenazine; Haloperidol;

2007
Centrally mediated drug-induced hyperglycemia in mice.
    Neuropharmacology, 1983, Volume: 22, Issue:3

    Topics: Animals; Blood Glucose; Central Nervous System; Cyproheptadine; Haloperidol; Hyperglycemia; Male; Me

1983
Blood brain barrier destruction in hyperglycemic chorea in a patient with poorly controlled diabetes.
    Journal of the neurological sciences, 1999, Feb-01, Volume: 163, Issue:1

    Topics: Anti-Dyskinesia Agents; Basal Ganglia; Blood-Brain Barrier; Chorea; Corpus Striatum; Cysteine; Diabe

1999
Non-ketotic hyperglycemia in a young woman, presenting as hemiballism-hemichorea.
    Acta neurologica Scandinavica, 1999, Volume: 100, Issue:6

    Topics: Acute Disease; Adult; Anti-Dyskinesia Agents; Brain; Chorea; Diagnosis, Differential; Dyskinesias; F

1999
Glucose-insulin metabolism in chronic schizophrenia.
    Diseases of the nervous system, 1976, Volume: 37, Issue:2

    Topics: Adult; Blood Glucose; Diabetes Complications; Glucose; Glucose Tolerance Test; Haloperidol; Humans;

1976
Increased incidence of neuroleptic-induced perioral movements in the rat by hyperglycemia.
    The International journal of neuroscience, 1990, Volume: 50, Issue:3-4

    Topics: Alloxan; Animals; Blood Glucose; Dyskinesia, Drug-Induced; Female; Haloperidol; Hyperglycemia; Rats;

1990